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  1. No Access

    Article

    Prognostic significance of general immune competence in acute leukemia

    The prognostic significance of lymphocyte transformation rate, E-RFC%, 29°C E-RFC%, serum IgG, IgA, IgM and C3 levels were studied in 286 patients with acute leukemia. In acute lymphoblastic leukemia (ALL), th...

    Li Bai-Ling, Hu Jie, Ye Jia, Wan **ao-Feng in Medical Oncology and Tumor Pharmacotherapy (1990)

  2. No Access

    Article

    Association of Vimentin overexpression and hepatocellular carcinoma metastasis

    The poor prognosis of hepatocellular carcinoma (HCC) has been associated with recurrence and metastasis. Recently, we established a pair of HCC cell lines from a primary (H2-P) and its matched metastatic (H2-M...

    Liang Hu, Sze Hang Lau, Chi-Hung Tzang, Jian-Ming Wen, Weisheng Wang, Dan **e in Oncogene (2004)

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    Article

    Epstein–Barr virus latent membrane protein 1 induces micronucleus formation, represses DNA repair and enhances sensitivity to DNA-damaging agents in human epithelial cells

    The latent membrane protein 1 (LMP1) of Epstein–Barr virus (EBV) is a viral oncogene and it is essential for the transformation of resting B cells by the virus. The protein acts as a ligand-less membrane recep...

    Ming-Tsan Liu, Yi-Ren Chen, Shu-Chuan Chen, Chi-Yuan Hu, Chang-Shen Lin in Oncogene (2004)

  4. No Access

    Article

    Why Taiwanese hospice patients want to stay in hospital: health-care professionals’ beliefs and solutions

    Patient-related barriers and their solution in the planning of discharge to palliative home care were investigated through a nationwide survey conducted in Taiwan. Of 250 questionnaires sent to palliative care...

    Wen-Yu Hu, Tai-Yuan Chiu, Yih-Ru Cheng, Rong-Bin Chuang in Supportive Care in Cancer (2004)

  5. No Access

    Article

    Factors that influence physicians in providing palliative care in rural communities in Taiwan

    To identify the willingness, influencing factors, and educational needs of community physicians in providing palliative care in the rural areas of Taiwan.

    Wen-**g Liu, Wen-Yu Hu, Yie-Fong Chiu, Tai-Yuan Chiu in Supportive Care in Cancer (2005)

  6. No Access

    Article

    Effects of educational intervention on nurses’ knowledge, attitudes, and behavioral intentions toward supplying artificial nutrition and hydration to terminal cancer patients

    This study aimed to investigate the effects of educational intervention on nurses’ knowledge, attitudes, and behavioral intentions regarding supplying artificial nutrition and hydration (ANH) to terminal cance...

    Li-Shan Ke, Tai-Yuan Chiu, Wen-Yu Hu, Su-Shun Lo in Supportive Care in Cancer (2008)

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    Article

    Surgery for Gastrointestinal Stromal Tumors of the Duodenum

    Duodenal gastrointestinal stromal tumors (GISTs) represent a unique dilemma with varied surgical treatment options. However, the impact of operative methods on disease recurrence has never been addressed.

    Yu-Wen Tien MD, Chih-Yuan Lee MD, Chun-Chieh Huang MD in Annals of Surgical Oncology (2010)

  8. No Access

    Article

    Correlation between the expression of the BAG-1 gene and clinicopathologic factors in colorectal cancer

    The present study aims to investigate the expression and significance of the anti-apoptotic gene Bag-1 in colorectal cancer and to evaluate the relationship between the gene and the disease.

    Nian-Feng Sun, Qing-Yi Meng, San-Yuan Hu in Journal of Cancer Research and Clinical On… (2011)

  9. No Access

    Article

    Inhibitory effects of Ginsenoside Rb1 on apoptosis caused by HSV-1 in Human Glioma Cells

    To investigate the inhibitory effects of Ginsenoside Rb1 (GRb1) on apoptosis caused by Herpes Simplex Virus-1(HSV-1) in Human Glioma Cells (U251), U251 cells were infected by HSV-1 at a multiplicity of infecti...

    Yuan-Yuan Liang, Bin Wang, Dong-Meng Qian, Ling Li, Zhi-Hao Wang in Virologica Sinica (2012)

  10. Article

    Open Access

    Expression of TRAF6 and ubiquitin mRNA in skeletal muscle of gastric cancer patients

    To investigate the prognostic significance of tumor necrosis factor receptor (TNFR),-associated factor 6 (TRAF6),-and ubiquitin in gastric cancer patients.

    Yuan-Shui Sun, Zai-Yuan Ye, Zhen-Yuan Qian in Journal of Experimental & Clinical Cancer … (2012)

  11. No Access

    Article

    Increased tumor-infiltrating CD8+Foxp3+ T lymphocytes are associated with tumor progression in human gastric cancer

    CD8+Foxp3+ T lymphocytes have been detected in tumors. However, the distribution, phenotypic features, and regulation of these cells in gastric cancer remain unknown.

    Liu-sheng Peng, Yuan Zhuang, Yun Shi, Yong-liang Zhao in Cancer Immunology, Immunotherapy (2012)

  12. No Access

    Article

    Increased intratumoral IL-22-producing CD4+ T cells and Th22 cells correlate with gastric cancer progression and predict poor patient survival

    IL-22-producing CD4+ T cells (IL-22+CD4+ T cells) and Th22 cells (IL-22+IL-17IFN-γCD4+ T cells) represent newly discovered T-cell subsets, but their nature, regulation, and clinical relevance in gastric cancer ...

    Yuan Zhuang, Liu-sheng Peng, Yong-liang Zhao, Yun Shi in Cancer Immunology, Immunotherapy (2012)

  13. No Access

    Article

    Gamma-Aminobutyric Acid Binds to GABAB Receptor to Inhibit Cholangiocarcinoma Cells Growth via the JAK/STAT3 Pathway

    Gamma-aminobutyric acid (GABA) has been reported to inhibit the growth of cholangiocarcinoma QBC939 cells, but the mechanisms are still not fully understood.

    Qiang Huang, Cheng-lin Zhu, Chen-hai Liu, Fang **e in Digestive Diseases and Sciences (2013)

  14. No Access

    Article

    Diminishing prognostic role of preexisting diabetes mellitus for patients with diffuse large B-cell lymphoma in the rituximab era

    Rituximab reforms the treatment of diffuse large B-cell lymphoma (DLBCL) and the prognostic significance of baseline patient features should be reevaluated. Few population-based studies have investigated the a...

    Hsueh-Ju Lu, Yu-Chung Huang, Chun-Yu Liu, Man-Hsin Hung in Annals of Hematology (2013)

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    Article

    TLR4-dependant immune response, but not hepatitis B virus reactivation, is important in radiation-induced liver disease of liver cancer radiotherapy

    Toll-like receptor 4 (TLR4) is an important trigger of the immune response against hepatitis B virus (HBV) infection and liver injuries. The roles of HBV reactivation versus TLR4-dependant immune response may ...

    Zhi-Feng Wu, **ao-Hui Zhou, Yun-Wen Hu, Le-Yuan Zhou in Cancer Immunology, Immunotherapy (2014)

  16. No Access

    Article

    Biological Characteristics and Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors Efficacy of EGFR Mutation and its Subtypes in Lung Adenocarcinoma

    Mutation of epidermal growth factor receptor (EGFR) gene has been reported to be present in lung adenocarcinoma (LAC). In this study, we extensively investigated the impact of patients’ biological characterist...

    Rong-li Lu, Cheng-** Hu, Hua-** Yang, Yuan-yuan Li in Pathology & Oncology Research (2014)

  17. No Access

    Article

    Chlorhexidine for the prevention of bloodstream infection associated with totally implantable venous ports in patients with solid cancers

    To evaluate the preventive effects of topical skin disinfection with chlorhexidine on bloodstream infection (BSI) associated with totally implantable venous port (Port-A).

    Hsiang-Fong Kao, I-Chun Chen, Chiun Hsu, Sin-Yuan Chang in Supportive Care in Cancer (2014)

  18. No Access

    Article

    Absolute lymphocyte count and risk of short-term infection in patients with immune thrombocytopenia

    Patients with immune thrombocytopenia (ITP) may be at increased risk of infection because of the steroids and other immunosuppressive agents used in its treatment. This study aimed to identify events that are ...

    Ming-Hung Hu, Yuan-Bin Yu, Yu-Chung Huang, Jyh-Pyng Gau in Annals of Hematology (2014)

  19. No Access

    Article

    Hospice shared-care saved medical expenditure and reduced the likelihood of intensive medical utilization among advanced cancer patients in Taiwan—a nationwide survey

    Hospice shared care (HSC) is a new care model that has been adopted to treat inpatient advanced cancer patients in Taiwan since 2005. Our aim was to assess the effect of HSC on medical expenditure and the like...

    Wen-Yuan Lin, Tai-Yuan Chiu, Chih-Te Ho, Lance E. Davidson in Supportive Care in Cancer (2014)

  20. Article

    Open Access

    Functional variants at the 21q22.3 locus involved in breast cancer progression identified by screening of genome-wide estrogen response elements

    Estrogen forms a complex with the estrogen receptor (ER) that binds to estrogen response elements (EREs) in the regulatory region of estrogen-responsive genes and regulates their transcription. Sequence varian...

    Chia-Ni Hsiung, Hou-Wei Chu, Yuan-Ling Huang, Wen-Cheng Chou in Breast Cancer Research (2014)

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