60 Result(s)
within
Article
**n-Yuan Hu
Internal Medicine
-
Article
Prognostic significance of general immune competence in acute leukemia
The prognostic significance of lymphocyte transformation rate, E-RFC%, 29°C E-RFC%, serum IgG, IgA, IgM and C3 levels were studied in 286 patients with acute leukemia. In acute lymphoblastic leukemia (ALL), th...
-
Article
Association of Vimentin overexpression and hepatocellular carcinoma metastasis
The poor prognosis of hepatocellular carcinoma (HCC) has been associated with recurrence and metastasis. Recently, we established a pair of HCC cell lines from a primary (H2-P) and its matched metastatic (H2-M...
-
Article
Epstein–Barr virus latent membrane protein 1 induces micronucleus formation, represses DNA repair and enhances sensitivity to DNA-damaging agents in human epithelial cells
The latent membrane protein 1 (LMP1) of Epstein–Barr virus (EBV) is a viral oncogene and it is essential for the transformation of resting B cells by the virus. The protein acts as a ligand-less membrane recep...
-
Article
Correlation between the expression of the BAG-1 gene and clinicopathologic factors in colorectal cancer
The present study aims to investigate the expression and significance of the anti-apoptotic gene Bag-1 in colorectal cancer and to evaluate the relationship between the gene and the disease.
-
Article
The novel ATP-sensitive potassium channel opener iptakalim prevents insulin resistance associated with hypertension via restoring endothelial function
To investigate the effects of iptakalim on endothelial dysfunction induced by insulin resistance (IR) and to determine whether iptakalim improved IR associated with hypertension in fructose-fed rats (FFRs) and...
-
Article
Huperzine A derivative M3 protects PC12 cells against sodium nitroprusside-induced apoptosis
To investigate the effects of M3, a derivative of huperzine A, on the apoptosis induced by sodium nitroprusside (SNP) in PC12 cells.
-
Article
Characterization of the immune responses elicited by baculovirus-based vector vaccines against influenza virus hemagglutinin
To compare the specific immune responses elicited by different baculovirus vectors in immunized mice.
-
Article
Anisomycin induces glioma cell death via down-regulation of PP2A catalytic subunit in vitro
To examine the effects of anisomycin on glioma cells and the related mechanisms in vitro.
-
Article
Open AccessThe interventional therapy for diabetic peripheral artery disease
Diabetic peripheral arterial disease is the main cause of lower limb amputation in patients with diabetes. To summarize the technique and experiences and evaluate the clinical effects of blood vessel intervent...
-
Article
Therapeutic effects of mesenchymal stem cell-derived microvesicles on pulmonary arterial hypertension in rats
Microvesicles (MVs) are nanoscale membrane fragments released from virtually all cell types upon activation or apoptosis, and may contribute to the beneficial effects of stem cell therapy. In this study, we in...
-
Article
Arctigenin enhances swimming endurance of sedentary rats partially by regulation of antioxidant pathways
Arctigenin, a phenylpropanoid dibenzylbutyrolactone lignan found in traditional Chinese herbs, has been determined to exhibit a variety of pharmacological activities, including anti-tumor, anti-inflammation, n...
-
Article
Risk factors for colorectal neoplasms based on colonoscopy and pathological diagnoses of Chinese citizens: a multicenter, case-control study
Since observational data in the urban residents are required to better assess the risk factors of colorectal neoplasm occurrence and the effectiveness of colonoscopy screening and surveillance, we conducted a ...
-
Article
Bigelovin inhibits STAT3 signaling by inactivating JAK2 and induces apoptosis in human cancer cells
To study the function and mechanism of bigelovin, a sesquiterpene lactone from the flower of Chinese herb Inula hupehensis, in regulating JAK2/STAT3 signaling and cancer cell growth.
-
Article
Open AccessThe prevalence, incidence, management and risks of atrial fibrillation in an elderly Chinese population: a prospective study
There is limited information on prevalent and incident atrial fibrillation in Chinese. We aimed to investigate the prevalence, incidence, management and risks of atrial fibrillation in an elderly Chinese popul...
-
Article
MK-2206 induces apoptosis of AML cells and enhances the cytotoxicity of cytarabine
Genetic alterations in the PI3K/AKT cascade have been linked to various human cancers including acute myeloid leukemia (AML) and have emerged to be promising targets for treatment. In this study, we explored t...
-
Article
Open AccessPrognostic factors for severe Pneumocystis jiroveci pneumonia of non-HIV patients in intensive care unit: a bicentric retrospective study
Pneumocystis jiroveci pneumonia (PJP) in non-HIV patients is still a challenge for intensivists. The aim of our study was to evaluate mortality predictors of PJP patients requiring Intensive care unit (ICU) admis...
-
Article
Open AccessClinical manifestations of severe enterovirus 71 infection and early assessment in a Southern China population
Enterovirus 71 (EV-A71) shows a potential of rapid death, but the natural history of the infection is poorly known. This study aimed to examine the natural history of EV-A71 infection.
-
Article
Open AccessEpidemiological and molecular characteristics of emergent dengue virus in Yunnan Province near the China-Myanmar-Laos border, 2013–2015
Yunnan Province is located in southwestern China and neighbors the Southeast Asian countries, all of which are dengue-endemic areas. In 2000–2013, sporadic imported cases of dengue fever (DF) were reported alm...
-
Article
Open AccessSacroiliac joint tuberculosis: surgical management by posterior open-window focal debridement and joint fusion
Sacroiliac joint tuberculosis(SJT) is relatively uncommon, but it may cause severe sacroiliac joint destruction and functional disorder. Few studies in the literature have been presented on SJT, reports of sur...
-
Article
Open AccessOmentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines
Osteoporosis is a frequent complication of chronic inflammatory diseases and increases in the pro-inflammatory cytokines make an important contribution to bone loss by promoting bone resorption and impairing b...
