11 Result(s)
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Article
**jiang Yao
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessExploring the “gene–metabolite” network of ischemic stroke with blood stasis and toxin syndrome by integrated transcriptomics and metabolomics strategy
A research model combining a disease and syndrome can provide new ideas for the treatment of ischemic stroke. In the field of traditional Chinese medicine, blood stasis and toxin (BST) syndrome is considered a...
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Open AccessSingle-cell metabolic fingerprints discover a cluster of circulating tumor cells with distinct metastatic potential
Circulating tumor cells (CTCs) are recognized as direct seeds of metastasis. However, CTC count may not be the “best” indicator of metastatic risk because their heterogeneity is generally neglected. In this st...
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Open AccessBiochar and fulvic acid amendments mitigate negative effects of coastal saline soil and improve crop yields in a three year field trial
China with large area of land planted with crops are suffering secondary salinization in coastal area for the lack of fresh water and saltwater intrusion to the groundwater. The purpose of this study was to in...
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Open AccessReducing aggregation caused quenching effect through co-assembly of PAH chromophores and molecular barriers
The features of well-conjugated and planar aromatic structures make π-conjugated luminescent materials suffer from aggregation caused quenching (ACQ) effect when used in solid or aggregated states, which great...
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Open AccessLupus nephritis pathology prediction with clinical indices
Effective treatment of lupus nephritis and assessment of patient prognosis depend on accurate pathological classification and careful use of acute and chronic pathological indices. Renal biopsy can provide mos...
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Open AccessQM/MM free energy Simulations of an efficient Gluten Hydrolase (Kuma030) Implicate for a Reactant-State Based Protein-Design Strategy for General Acid/Base Catalysis
It is a grand attraction for contemporary biochemists to computationally design enzymes for novel chemical transformation or improved catalytic efficiency. Rosetta by Baker et al. is no doubt the leading software...
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Open AccessChromosome structural variation of two cultivated tetraploid cottons and their ancestral diploid species based on a new high-density genetic map
A high-resolution genetic map is a useful tool for assaying genomic structural variation and clarifying the evolution of polyploid cotton. A total of 36956 SSRs, including 11289 released in previous studies an...
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Open AccessRole of Histidine 547 of Human Dopamine Transporter in Molecular Interaction with HIV-1 Tat and Dopamine Uptake
HIV-1 Tat plays an important role in HIV-associated neurocognitive disorders (HAND) by disrupting neurotransmission including dopamine uptake by human dopamine transporter (hDAT). Previous studies have demonst...
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Open AccessUnexpected Reaction Pathway for butyrylcholinesterase-catalyzed inactivation of “hunger hormone” ghrelin
Extensive computational modeling and simulations have been carried out, in the present study, to uncover the fundamental reaction pathway for butyrylcholinesterase (BChE)-catalyzed hydrolysis of ghrelin, demon...
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Open AccessLivestock-associated methicillin and multidrug resistant S. aureus in humans is associated with occupational pig contact, not pet contact
This study aimed to explore the association of livestock-associated S. aureus with occupational pig contact and pet contact. In this cross-sectional study, 1,422 participants (including 244 pig workers, 200 pet-o...
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Open AccessMetro system in Guangzhou as a hazardous reservoir of methicillin-resistant Staphylococci: findings from a point-prevalence molecular epidemiologic study
Staphylococci are common causes of healthcare-associated and community-associated infections. However, limited data are available on the prevalence, phenotypes and molecular characteristics of Staphylococci in me...
