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Article
Concepts and Reasoning: a Conceptual Review and Analysis of Logical Issues in Empirical Social Science Research
A substantial number of social science studies have shown a lack of conceptual clarity, inadequate understanding of the nature of the empirical research approaches, and undue preference for deduction, which ha...
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Article
Open AccessExploring the “gene–metabolite” network of ischemic stroke with blood stasis and toxin syndrome by integrated transcriptomics and metabolomics strategy
A research model combining a disease and syndrome can provide new ideas for the treatment of ischemic stroke. In the field of traditional Chinese medicine, blood stasis and toxin (BST) syndrome is considered a...
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Article
Open AccessEvaluating the reliability of the lateral femoral condyle measuring methods by different modalities for patients with lateral patellar dislocation
A variety of measurement methods and imaging modalities are in use to quantify the morphology of lateral femoral condyle (LFC), but the most reliable method remains elusive in patients with lateral patellar di...
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Article
Open AccessUnveiling Organic Electrode Materials in Aqueous Zinc-Ion Batteries: From Structural Design to Electrochemical Performance
A comprehensive introduction into organic cathode materials for aqueous zinc-ion batteries with specific focus on their structural–property relationship based on the variations...
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Article
Recent advances in organic cathodes for dual-ion batteries
Dual-ion batteries (DIBs), a novel energy storage technology wherein both anions and cations actively participate in the electrochemical redox process, hold great promise for further cost reduction in chemical...
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Article
Substrate Inhibition of the Highly Efficient PET Hydrolase
Polyethylene terephthalate (PET) is one of the most abundant polyester materials used in daily life and it is also one of the culprits of environmental pollution. ICCG (F243I/D238C/S283C/Y127G) is a quadruple ...
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Article
Climate change versus the water–energy–food nexus: the oldness or newness of the scientific issues as a factor in the deficit model and the hierarchy of response model
Environmental issues need public support to be solved. But the theoretical model that supports providing the public scientific information to enhance their support for scientific issues, the deficit model, is ...
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Article
Formation of the Primary Second Phases and their Influence on the Mechanical Properties of an as-Cast Al–Li–Mg Alloy with Multi-Microalloying (Sc, Zr, Er and Ti)
As-cast Al–Li–Mg system alloys are a good prospect for use in transport vehicles due to the ultra-low density of Li and Mg. However, low ductility and strength restricts its large-scale application. This work ...
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Article
Long noncoding RNA MAFG-AS1 enhances proliferation, invasion, and epithelial–mesenchymal transition of melanoma cells through promoting KIT expression by competitively binding to miR-331-3p
Melanoma is a malignant skin cancer. This paper is dedicated to investigate the disease mechanism in regard to the axis of long noncoding RNA MAFG antisense 1 (MAFG-AS1)/microRNA (miR)-331-3p/KIT.
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Article
A kernel search algorithm for virtual machine consolidation problem in cloud computing
Virtual machine consolidation refers to the process of reallocating virtual machines across a set of target servers. It can be formulated as a mixed integer linear programming problem, which is known to be NP-...
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Article
Femoral anteversion measured by the surgical transepicondylar axis is a reliable parameter for evaluating femoral rotational deformities in patients with patellar dislocation
To verify whether femoral anteversion measured by the surgical transepicondylar axis (S-FA) is a reliable parameter for evaluating femoral rotational deformities and to provide an indication for derotational d...
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Article
Open AccessDapagliflozin protects against dilated cardiomyopathy progression by targeting NLRP3 inflammasome activation
Dilated cardiomyopathy (DCM) is the major cause of heart failure and has a poor prognosis. The accumulating evidence points to an essential role of the inflammatory component in the process of DCM. Inhibitors...
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Article
Open AccessSingle-cell metabolic fingerprints discover a cluster of circulating tumor cells with distinct metastatic potential
Circulating tumor cells (CTCs) are recognized as direct seeds of metastasis. However, CTC count may not be the “best” indicator of metastatic risk because their heterogeneity is generally neglected. In this st...
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Article
The impact of land use on stream macroinvertebrates: a bibliometric analysis for 2010–2021
Changes in stream biodiversity are now mainly driven by land-use development. However, a literature review on the impact of land use on stream macroinvertebrates is lacking, especially a scientometric review. ...
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Article
Soil organic carbon distribution and storage along reclamation chronosequences in a typical coastal farming area, Eastern China
Soil organic carbon (SOC) is an important indicator for soil quality evaluation. It is closely associated with soil fertility, and also has a great impact on the terrestrial carbon cycle. In this study, the di...
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Article
Open AccessStages of preadipocyte differentiation: biomarkers and pathways for extracellular structural remodeling
This study utilized bioinformatics to analyze the underlying biological mechanisms involved in adipogenic differentiation, synthesis of the extracellular matrix (ECM), and angiogenesis during preadipocyte diff...
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Article
How viscous is the beating heart? Insights from a computational study
Understanding tissue rheology is critical to accurately model the human heart. While the elastic properties of cardiac tissue have been extensively studied, its viscous properties remain an issue of ongoing de...
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Article
Solute Segregation to Grain Boundaries in Al: A First-Principles Evaluation
Solute-induced grain boundary (GB) strengthening is effective in improving the toughness and tensile strength of polycrystalline alloys. In this work, GB segregation behaviors of solute elements in Al alloys a...
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Article
Ammonia Monooxygenase Activity Connects Nitrification Rate with Dominant Edaphic Properties Under Salinity Stress in Coastal Fluvo-aquic Soil
Nitrification is a key player in biogeochemical cycling of nitrogen, and there is a need to regulate the nitrification for nitrogen loss reduction in agroecosystems. The current study aimed to identify the int...
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Article
Effects of Soil Salinity on Nitrification and Ammonia-Oxidizing Microorganisms in Coastal Reclaimed Farmland Soil
Nitrification, which is controlled by ammonia-oxidizing archaea (AOA) and bacteria (AOB), is the key step in the nitrogen cycle. Coastal reclaimed farmland is in the conversion stage from coastal mudflat to cu...