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  1. No Access

    Article

    A new hybrid lattice structure with improved modulus, strength and energy absorption properties

    In this paper, a hybrid octagonal simple-cubic (OSC) lattice structure is obtained by combining the cell configurations of the bending-dominated octagonal lattice and the stretching-dominated SC lattice. Finit...

    LingBo Li, Fan Yang, Peng Wang, ZhengMiao Guo in Science China Technological Sciences (2023)

  2. Article

    Open Access

    Structural basis of protein condensation on microtubules underlying branching microtubule nucleation

    Targeting protein for Xklp2 (TPX2) is a key factor that stimulates branching microtubule nucleation during cell division. Upon binding to microtubules (MTs), TPX2 forms condensates via liquid-liquid phase sepa...

    Changmiao Guo, Raymundo Alfaro-Aco, Chunting Zhang… in Nature Communications (2023)

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  3. Article

    Open Access

    Magic-angle-spinning NMR structure of the kinesin-1 motor domain assembled with microtubules reveals the elusive neck linker orientation

    Microtubules (MTs) and their associated proteins play essential roles in maintaining cell structure, organelle transport, cell motility, and cell division. Two motors, kinesin and cytoplasmic dynein link the M...

    Chunting Zhang, Changmiao Guo, Ryan W. Russell, Caitlin M. Quinn… in Nature Communications (2022)

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  4. No Access

    Article

    Map** protein–protein interactions by double-REDOR-filtered magic angle spinning NMR spectroscopy

    REDOR-based experiments with simultaneous 1H–13C and 1H−15N dipolar dephasing are explored for investigating intermolecular protein–protein interfaces in complexes formed by a U–13C,15N-labeled protein and its na...

    Changmiao Guo, Guang** Hou, **ngyu Lu, Tatyana Polenova in Journal of Biomolecular NMR (2017)

  5. No Access

    Article

    Combined zero-quantum and spin-diffusion mixing for efficient homonuclear correlation spectroscopy under fast MAS: broadband recoupling and detection of long-range correlations

    Fast magic angle spinning (MAS) NMR spectroscopy is emerging as an essential analytical and structural biology technique. Large resolution and sensitivity enhancements observed under fast MAS conditions enable...

    **ngyu Lu, Changmiao Guo, Guang** Hou, Tatyana Polenova in Journal of Biomolecular NMR (2015)

  6. No Access

    Article

    Fast magic angle spinning NMR with heteronucleus detection for resonance assignments and structural characterization of fully protonated proteins

    Heteronucleus-detected dipolar based correlation spectroscopy is established for assignments of 1H, 13C, and 15N resonances and structural analysis in fully protonated proteins. We demonstrate that 13C detected 3...

    Changmiao Guo, Guang** Hou, **ngyu Lu, Bernie O’Hare… in Journal of Biomolecular NMR (2014)

  7. No Access

    Article

    Investigation on hot workability characteristics of Inconel 625 superalloy using processing maps

    Hot compression tests of the commercial Inconel 625 were performed in the temperature range of 950–1200 °C and strain rate range of 0.01–10 s−1. The flow behavior and processing maps were investigated using the c...

    Shengli Guo, Defu Li, Qingmiao Guo, Zhigang Wu… in Journal of Materials Science (2012)

  8. No Access

    Article

    Nucleation mechanisms of dynamic recrystallization in Inconel 625 superalloy deformed with different strain rates

    The effects of strain rates on the hot working characteristics and nucleation mechanisms of dynamic recrystallization (DRX) were studied by optical microscopy and electron backscatter diffraction (EBSD) techni...

    Qingmiao Guo, Defu Li, Haijian Peng, Shengli Guo, Jie Hu, Peng Du in Rare Metals (2012)