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  1. Article

    Open Access

    Crotonylated BEX2 interacts with NDP52 and enhances mitophagy to modulate chemotherapeutic agent-induced apoptosis in non-small-cell lung cancer cells

    Brain expressed X-linked gene 2 (BEX2) encoded protein was originally identified to promote transcription by interacting with several transcription factors in the DNA–binding complexes. Recently, BEX2 was found t...

    Ning Mu, Yu Wang, **aopeng Li, Zhiyuan Du, Yingdi Wu, Min Su in Cell Death & Disease (2023)

  2. Article

    Correction to: MAP2K6 remodels chromatin and facilitates reprogramming by activating Gatad2b-phosphorylation dependent heterochromatin loosening

    Guangsuo **ng, Zichao Liu, Luyuan Huang, Danyun Zhao in Cell Death & Differentiation (2022)

  3. No Access

    Article

    Plin2-mediated lipid droplet mobilization accelerates exit from pluripotency by lipidomic remodeling and histone acetylation

    Metabolic switch is critical for cell fate determination through metabolic functions, epigenetic modifications, and gene expression. However, the mechanisms underlying these alterations and their functional ro...

    Yi Wu, Keshi Chen, Linpeng Li, Zhihong Hao, Tianyu Wang in Cell Death & Differentiation (2022)

  4. No Access

    Article

    MAP2K6 remodels chromatin and facilitates reprogramming by activating Gatad2b-phosphorylation dependent heterochromatin loosening

    Somatic cell reprogramming is an ideal model for studying epigenetic regulation as it undergoes dramatic chromatin remodeling. However, a role for phosphorylation signaling in chromatin protein modifications f...

    Guangsuo **ng, Zichao Liu, Luyuan Huang, Danyun Zhao in Cell Death & Differentiation (2022)

  5. Article

    Open Access

    YIPF2 promotes chemotherapeutic agent-mediated apoptosis via enhancing TNFRSF10B recycling to plasma membrane in non-small cell lung cancer cells

    Non-small cell lung cancer (NSCLC) is the most common histological type of lung cancer, and the identification of the apoptotic process of NSCLC is vital for its treatment. Usually, both the expression level a...

    Yingying Wang, Sen Guo, Dongmei Li, Yongkang Tang, Lei Li, Ling Su in Cell Death & Disease (2020)

  6. Article

    Open Access

    A novel mitochondrial micropeptide MPM enhances mitochondrial respiratory activity and promotes myogenic differentiation

    Micropeptides belong to a class of newly identified small molecules with <100 amino acids in length, and their functions remain largely unknown. Here, we identified a novel muscle-enriched micropeptide that wa...

    Yi-Fang Lin, Man-Huan **ao, Hua-**ng Chen, Yu Meng, Na Zhao in Cell Death & Disease (2019)

  7. Article

    Open Access

    Polybrene induces neural degeneration by bidirectional Ca2+ influx-dependent mitochondrial and ER–mitochondrial dynamics

    Hexadimethrine bromide (Polybrene) was once used clinically as a heparin neutralizer and has recently found use as a promoter in virus-mediated gene therapy trials and gene transfer in research. However, the p...

    Feixiang Bao, Hongyan Shi, Mi Gao, Liang Yang, Lingyan Zhou in Cell Death & Disease (2018)

  8. Article

    Open Access

    Gadd45a opens up the promoter regions of miR-295 facilitating pluripotency induction

    MicroRNAs (miRNAs) play crucial roles in the establishment of pluripotent state by controlling pluripotent network. However, the molecular mechanisms controlling miRNAs during somatic cell reprogramming remain...

    Linpeng Li, Keshi Chen, Yi Wu, Qi Long, Danyun Zhao, Bochao Ma in Cell Death & Disease (2017)

  9. Article

    Open Access

    Golgi-associated LC3 lipidation requires V-ATPase in noncanonical autophagy

    Autophagy is an evolutionarily conserved catabolic process by which cells degrade intracellular proteins and organelles in the lysosomes. Canonical autophagy requires all autophagy proteins (ATGs), whereas non...

    Ying Gao, Yajun Liu, Liang Hong, Zuolong Yang, **nran Cai in Cell Death & Disease (2016)

  10. No Access

    Article

    Mitochondrial fusion provides an ‘initial metabolic complementation’ controlled by mtDNA

    Heteroplasmic cells, harboring both mutant and normal mitochondrial DNAs (mtDNAs), must accumulate mutations to a threshold level before respiratory activity is affected. This phenomenon has led to the hypothe...

    Liang Yang, Qi Long, **glei Liu, Haite Tang in Cellular and Molecular Life Sciences (2015)