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  1. Article

    Open Access

    Deep learning image reconstruction generates thinner slice iodine maps with improved image quality to increase diagnostic acceptance and lesion conspicuity: a prospective study on abdominal dual-energy CT

    To assess the improvement of image quality and diagnostic acceptance of thinner slice iodine maps enabled by deep learning image reconstruction (DLIR) in abdominal dual-energy CT (DECT).

    **gyu Zhong, Lingyun Wang, Chao Yan, Yue **ng, Yangfan Hu in BMC Medical Imaging (2024)

  2. Article

    Open Access

    Natural evidence of coronaviral 2′-O-methyltransferase activity affecting viral pathogenesis via improved substrate RNA binding

    Previous studies through targeted mutagenesis of K-D-K-E motif have demonstrated that 2′-O-MTase activity is essential for efficient viral replication and immune evasion. However, the K-D-K-E catalytic motif o...

    Jikai Deng, Shimin Yang, Yingjian Li, Xue Tan in Signal Transduction and Targeted Therapy (2024)

  3. Article

    Open Access

    The relationship between oxidative balance scores and chronic diarrhea and constipation: a population-based study

    Oxidative stress is closely related to gut health. Exposures to oxidative stress in one’s diet and lifestyle can be evaluated by the oxidative balance score (OBS). However, the relationship between OBS and int...

    Jiayan Hu, Hede Zou, **yun Qiao, Yuxi Wang, Mi Lv, Kunli Zhang in BMC Public Health (2024)

  4. Article

    Open Access

    Unraveling transcriptomic signatures and dysregulated pathways in systemic lupus erythematosus across disease states

    This study aims to elucidate the transcriptomic signatures and dysregulated pathways in patients with Systemic Lupus Erythematosus (SLE), with a particular focus on those persisting during disease remission.

    Frank Qingyun Wang, Li Shao, **ao Dang, Yong-Fei Wang in Arthritis Research & Therapy (2024)

  5. No Access

    Article

    Danlou Tablet Protects Against Myocardial Infarction Through Promoting eNOS-Dependent Endothelial Protection and Angiogenesis

    Myocardial infarction (MI) is one of the leading causes of death worldwide. Danlou tablet (Dan) is an effective traditional Chinese medicine for cardiac protection, although the underlying mechanism was not fu...

    Yujiao Zhu, Yibo Chai, Zhuhua Su, Weitong Qi in Journal of Cardiovascular Translational Re… (2024)

  6. Article

    Open Access

    Evaluation of canine adipose-derived mesenchymal stem cells for neurological functional recovery in a rat model of traumatic brain injury

    Traumatic brain injury (TBI) is a common condition in veterinary medicine that is difficult to manage.Veterinary regenerative therapy based on adipose mesenchymal stem cells seem to be an effective strategy fo...

    Wenkang Jiang, Huina Luo, Mingming Zhao, Quanbao Fan, Cailing Ye in BMC Veterinary Research (2024)

  7. Article

    Open Access

    Comparative study of ultrasound attenuation analysis and controlled attenuation parameter in the diagnosis and grading of liver steatosis in non-alcoholic fatty liver disease patients

    To assess the diagnostic performance of Ultrasound Attenuation Analysis (USAT) in the diagnosis and grading of hepatic steatosis in patients with non-alcoholic fatty liver disease (NAFLD) using Controlled Atte...

    Mengyun Wang, Shuzhen Tang, Guoqiu Li, Zhibin Huang, Sijie Mo in BMC Gastroenterology (2024)

  8. Article

    Open Access

    Impacts of Adaptive Statistical Iterative Reconstruction-V and Deep Learning Image Reconstruction Algorithms on Robustness of CT Radiomics Features: Opportunity for Minimizing Radiomics Variability Among Scans of Different Dose Levels

    This study aims to investigate the influence of adaptive statistical iterative reconstruction-V (ASIR-V) and deep learning image reconstruction (DLIR) on CT radiomics feature robustness. A standardized phantom...

    **gyu Zhong, Zhiyuan Wu, Lingyun Wang in Journal of Imaging Informatics in Medicine (2024)

  9. No Access

    Article

    Fully automated artificial intelligence-based coronary CT angiography image processing: efficiency, diagnostic capability, and risk stratification

    To prospectively investigate whether fully automated artificial intelligence (FAAI)-based coronary CT angiography (CCTA) image processing is non-inferior to semi-automated mode in efficiency, diagnostic abilit...

    Ya** Zhang, Yan Feng, Jianqing Sun, Lu Zhang, Zhenhong Ding in European Radiology (2024)

  10. No Access

    Article

    Retrospective cohort evaluation of non-HIV Castleman disease from a single academic center in Bei**g, China

    The purpose is to ascertain the clinical impact of Castleman disease (CD) by reassessment of the real-world data from Peking University First Hospital (PKUFH). The results will contribute to the standardizatio...

    Meiyu Guo, Lin Nong, Mingyue Wang, Yang Zhang, Lihong Wang in Annals of Hematology (2024)

  11. Article

    Open Access

    KLF5 promotes esophageal squamous cell cancer through the transcriptional activation of FGFBP1

    Krüpple-like factor 5 (KLF5) is a zinc-finger-containing transcription factor implicated in several human malignancies, but its potential regulatory mechanisms implicated in esophageal squamous cell carcinoma ...

    Fengyun Wang, Ming Luo, Yufeng Cheng in Medical Oncology (2023)

  12. Article

    Open Access

    Effect of pre-use of Dexmedetomidine on the effective inhibitory dose of remimazolam tosilate on positive cardiovascular response in double-lumen endobronchial intubation: a clinical study

    Herein, the effect of pre-use of Dexmedetomidine(Dex) on the half-effective dose (ED50) and 95%-effective dose (ED95) of Remimazolam tosilate(RT) in inhibiting the positive cardiovascular response(CR) which me...

    Shiyou Wei, **aojuan Liu, Rui Chang, Xue Chen, Tao Zheng in BMC Anesthesiology (2023)

  13. No Access

    Article

    Real-world outcomes and prognostic factors among patients with acute myeloid leukemia treated with allogeneic hematopoietic stem cell transplantation

    Acute myeloid leukemia (AML) is a malignant lymphohematopoietic tumor that ranks among the most frequent indications for allogeneic hematopoietic stem cell transplantation (allo-HSCT). This article aims to pro...

    Qingya Wang, Zeyin Liang, Hanyun Ren, Yujun Dong, Yue Yin in Annals of Hematology (2023)

  14. No Access

    Article

    Sex- and age-specific prevalence and risk factors of depressive symptoms in Parkinson’s disease

    Although depressive symptoms are common in PD, few studies investigated sex and age differences in depressive symptoms. Our study aimed to explore the sex and age differences in the clinical correlates of depr...

    Lichao Niu, Cong Yao, Chuhao Zhang, Chi Zhou, Yun Fu in Journal of Neural Transmission (2023)

  15. No Access

    Article

    Improving lesion conspicuity in abdominal dual-energy CT with deep learning image reconstruction: a prospective study with five readers

    To evaluate image quality, diagnostic acceptability, and lesion conspicuity in abdominal dual-energy CT (DECT) using deep learning image reconstruction (DLIR) compared to those using adaptive statistical itera...

    **gyu Zhong, Lingyun Wang, Hailin Shen, Jianying Li, Wei Lu in European Radiology (2023)

  16. Article

    Open Access

    The Associations between Helicobacter Pylori immunoglobulin G seropositivity and body mass index in adults

    Inconsistent evidence currently exists regarding the associations between Helicobacter Pylori (H. pylori) infection and body mass index (BMI). The goal of the current study was to examine independent association...

    **ke Huang, Kunli Zhang, Fengyun Wang, Xudong Tang in BMC Infectious Diseases (2023)

  17. Article

    Open Access

    Construction of a risk model and prediction of prognosis and immunotherapy based on cuproptosis-related LncRNAs in the urinary system pan-cancer

    Urinary pan-cancer system is a general term for tumors of the urinary system including renal cell carcinoma (RCC), prostate cancer (PRAD), and bladder cancer (BLCA). Their location, physiological functions, an...

    Zhihui Ma, Haining Liang, Rongjun Cui, **li Ji in European Journal of Medical Research (2023)

  18. Article

    Chitinase 3-like 1: a Specifical Regulator of Myocardial Infarction

    Jianhua Yao, **xin **e, Huanxin Wang in Journal of Cardiovascular Translational Re… (2023)

  19. No Access

    Article

    Problematic Internet Use and Cyberbullying Perpetration Among Chinese Adolescents: the Mediating and Moderating Roles of Negative Emotions

    The present study examined the mediating and moderating roles of negative emotions on the association between problematic Internet use (PIU) and cyberbullying perpetration among adolescents. A sample of 831 ju...

    Ning He, Huizi Houmei, Mengyun Wang in International Journal of Mental Health and… (2023)

  20. Article

    Open Access

    Robustness of radiomics features of virtual unenhanced and virtual monoenergetic images in dual-energy CT among different imaging platforms and potential role of CT number variability

    To evaluate robustness of dual-energy CT (DECT) radiomics features of virtual unenhanced (VUE) image and virtual monoenergetic image (VMI) among different imaging platforms.

    **gyu Zhong, Zilai Pan, Yong Chen, Lingyun Wang, Yihan **a in Insights into Imaging (2023)

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