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    Article

    Sprod for de-noising spatially resolved transcriptomics data based on position and image information

    Spatially resolved transcriptomics (SRT) provide gene expression close to, or even superior to, single-cell resolution while retaining the physical locations of sequencing and often also providing matched path...

    Yunguan Wang, Bing Song, Shidan Wang, Mingyi Chen, Yang **e in Nature Methods (2022)

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    An integrated catalog of reference genes in the human gut microbiome

    Li et al. provide the largest catalog of genes in the human gut microbiome based on samples from >1,200 individuals across three continents.

    Junhua Li, Huijue Jia, **anghang Cai, Huanzi Zhong, Qiang Feng in Nature Biotechnology (2014)

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    Article

    Identification of cross-linked peptides from complex samples

    pLink, software for data analysis of cross-linked proteins coupled with mass spectrometry, estimates false discovery rate and enables analysis of protein complexes without extensive purification.

    Bing Yang, Yan-Jie Wu, Ming Zhu, Sheng-Bo Fan, **zhong Lin, Kun Zhang in Nature Methods (2012)

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    Article

    Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications

    Methods for profiling DNA methylation differ in the physical principles used to detect modified cytosines. Harris et al. compare the performances of four sequencing-based technologies for genome-wide analysis of ...

    R Alan Harris, Ting Wang, Cristian Coarfa, Raman P Nagarajan in Nature Biotechnology (2010)