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518 Result(s)
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New publishers for British Journal of Cancer
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Open AccessReturn to fertility after extended chemical castration with a GnRH antagonist
Antagonistic analogues of GnRH for the treatment of prostate cancer may be used clinically in persons for whom return to fertility after such treatment is important or desirable. The purpose of this study was,...
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Open AccessDecreased expression of the mannose 6- phosphate/insulin-like growth factor-II receptor promotes growth of human breast cancer cells
Loss or mutation of the mannose 6-phosphate/insulin-like growth factor-II receptor (M6P/IGF2R) has been found in breast cancer. However, whether or not decreased levels of functional M6P/IGF2R directly contrib...
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Open AccessFamilial Cervical Cancer: Case Reports, Review and Clinical Implications
We report three Dutch families with familial clustering of (pre)neoplastic cervical disease, review the literature on familial risks of cervical intraepithelial neoplasia (CIN) and cervical cancer, and discuss...
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Open AccessActivity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer
Matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9), and urokinase-type plasminogen activator (uPA) are involved in colorectal cancer invasion and metastasis. There is still debate whether t...
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Insulin-like growth factor signalling in oestrogen nonresponsive breast cancer cells
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Open AccessKu86 exists as both a full-length and a protease-sensitive natural variant in multiple myeloma cells
Truncated variants of Ku86 protein have previously been detected in 86% to 100% of freshly isolated patient multiple myeloma (MM) cells. Since, the Ku70/Ku86 heterodimer functions as the regulatory subunit of ...
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Open AccessAutoantibodies as potential biomarkers for breast cancer
Only a limited number of tumor markers for breast cancer are currently available. Antibodies to tumor-associated proteins may expand the number of available tumor markers for breast cancer and may be used toge...
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Open AccessEvaluation of high-risk Human papillomaviruses type distribution in cervical cancer in Sichuan province of China
Infection with high-risk human papillomavirus is an important factor associated with cervical cancer, and the distribution of HPV types varies greatly worldwide. Determination of type-specific HPV prevalence c...
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Open AccessPrognostic relevance of Centromere protein H expression in esophageal carcinoma
Many kinetochore proteins have been shown to be associated with human cancers. The aim of the present study was to clarify the expression of Centromere protein H (CENP-H), one of the fundamental components of ...
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Open AccessIn GFP with high risk HPV-18E6 fusion protein expressed 293T and MCF-7 cells, the endogenous wild-type p53 could be transiently phosphorylated at multiple sites
Infected cells recognize viral replication as a DNA damage stress and elicit the host surveillance mechanism to anti-virus infection. Modulation of the activity of tumor suppressor p53 is a key event in the re...
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Open AccessHaptoglobin phenotype is not a predictor of recurrence free survival in high-risk primary breast cancer patients
Better breast cancer prognostication may improve selection of patients for adjuvant therapy. We conducted a retrospective follow-up study in which we investigated sera of high-risk primary breast cancer patien...
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Open AccessImmunohistochemical characterization of subtypes of male breast carcinoma
Male breast cancer accounts for around 1% of all breast cancer cases but the incidence has risen in recent years. This study aimed to classify the molecular subtypes of male breast cancers based on the express...
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Open AccessOA01-06 LB. HIV-1 plasma RNA and risk of HIV-1 transmission
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Open AccessP15-08. Did unblinding affect HIV risk behaviour and risk perception in the HVTN503/Phambili study?
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Open AccessP08-04. The role of class I HLA-B and HLA-Cw in disease progression and maternal-infant HIV-1 transmission in a South African population
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Open AccessExpression of indoleamine 2,3-dioxygenase in nasopharyngeal carcinoma impairs the cytolytic function of peripheral blood lymphocytes
Tumor-specific cytotoxic T cells and infiltrating lymphocytes are frequently found in tumor tissues in patients with nasopharyngeal carcinoma (NPC). Most patients with NPC, however, especially those with advan...
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Open AccessMicroarray analysis of DNA damage repair gene expression profiles in cervical cancer cells radioresistant to 252Cf neutron and X-rays
The aim of the study was to obtain stable radioresistant sub-lines from the human cervical cancer cell line HeLa by prolonged exposure to 252Cf neutron and X-rays. Radioresistance mechanisms were investigated in ...
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Open AccessThe expression level of HJURP has an independent prognostic impact and predicts the sensitivity to radiotherapy in breast cancer
HJURP (Holliday Junction Recognition Protein) is a newly discovered gene reported to function at centromeres and to interact with CENPA. However its role in tumor development remains largely unknown. The goal ...
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Open AccessN-Acetylgalactosaminyltransferase-14 as a potential biomarker for breast cancer by immunohistochemistry
The post-translational modification of proteins, including glycosylation, differs between normal and tumor cells. The UDP-N-acetyl-D-galactosamine polypeptide N-acetylgalactosaminyltransferases (GalNAc-Tases) ...