612 Result(s)

Article

Intérêt de la cholangiographie à la Royer sous laparoscopie

F. -J. Traissac, J. -J. Ge, P. Gratadour in Acta Endoscopica (1972)

Article

Les lésions gastriques par sondes d'aspiration

F. -J. Traissac, J. -J. Ge, P. Gratadour in Acta Endoscopica (1972)

Article

Uptake, metabolism, and cytotoxicity of doxorubicin in human Ewing's sarcoma and rhabdomyosarcoma cells

Uptake, metabolism, and cytotoxicity of doxorubicin (DOX) in human Ewing's sarcoma (ES) and rhabdomyosarcoma (RS) cells were examined. Cellular uptake of DOX was determined by liquid scintillation spectrometry...

Michael W. DeGregorio, Ge Ming Lui, Bruce A. Macher… in Cancer Chemotherapy and Pharmacology (1984)

Article

Retardation of rat sciatic nerve regeneration after local application of minute doses of vincristine

The effect of vincristine on regeneration of rat sural and tibial nerves following a crush lesion of the sciatic nerve was studied in the pinch test. Vincristine locally applied through an osmotic minipump at ...

Gé S. F. Ruigt, Maria H. C. den Brok in Cancer Chemotherapy and Pharmacology (1995)

Article

Gene therapeutic approach to primary and metastatic brain tumors: I. CD44 variant pre-RNA alternative splicing as a CEPT control element

Our laboratory and others have shown alternative splicing of up to ten exons at a discrete extracellular site to be primarily responsible for the generation of CD44 variant (CD44v) isoforms. Based on clear dif...

David C. Asman, Julie F. Dirks, Lisheng Ge, Nicole M. Resnick… in Journal of Neuro-Oncology (1995)

Article

Gene therapeutic approaches to primary and metastatic brain tumors: II. Ribozyme-mediated suppression of CD44 expression

Glioblastomas are highly invasive intracerebral tumors that are known to express the CD44 cell adhesion molecule. Human glioma cell adhesion and invasionin vitro may in part be mediated by the interaction of CD44...

Lisheng Ge, Nicole M. Resnick, Linda K. Ernst… in Journal of Neuro-Oncology (1995)

Article

Analysis of the cellular origin of hepatocellular carcinoma by p53 genotype

The polymerase chain reaction andHaeIII enzymatic digestion were used to study the seventh exon of the p53 gene in 29 primary and recurrent hepatomas in paraffin-embedded samples from 11 patients. The mutation ra...

Bin He, Zhao-You Tang, Kang-Da Liu, Ge Zhou in Journal of Cancer Research and Clinical On… (1996)

Article

Expression of TrkA, TrkB and TrkC in human neuroblastomas

There is considerable interest in the role of the TRK family of neurotrophin receptors in regulating the survival, growth and differentiation of normal and neoplastic nerve cells. Indeed, there is increasing e...

Garrett M. Brodeur, Akira Nakagawara, Darrell J. Yamashiro… in Journal of Neuro-Oncology (1997)

Article

Identification and functional analysis of multiple murine myeloperoxidase (MPO) promoters and comparison with the human MPO promoter region

Myeloperoxidase (MPO) is an important component of the oxidative antibacterial defense system of granulocytes. Mammalian MPO gene expression has been most extensively studied in human and murine cells. Transcr...

W-G Zhao, JP Lu, A Regmi, GE Austin in Leukemia (1997)

Article

Clonality analysis of hematopoietic cell lineages in acute myeloid leukemia and translocation (8;21): only myeloid cells are part of the malignant clone

Bone marrow from six patients with acute myeloid leukemia (AML) and t(8;21) (q22;q22) or a variant t(8;13;21) was studied by simultaneous analysis of cell morphology and karyotype. Combination of May–Grünwald–...

K van Lom, A Hagemeijer, F Vandekerckhove, GE de Greef, N Sacchi, B Löwenberg in Leukemia (1997)

Article

Reconstruction and expression of chimeric anti-HBx antibody inEscherichia coli

The variable regions of murine monoclonal anti-HBx immunoglobulin and the constant region of human antibody were cloned by reverse transcriptpolymerase chain reaction (RT-PCR). The heavy-chain and light-chain ...

Ge Zhou, Kang-Da Liu, Zhao-You Tang… in Journal of Cancer Research and Clinical On… (1997)

Article

Development of an interphase fluorescent in situ hybridization (FISH) test to detect t(8;21) in AML patients

The translocation (8;21) is a chromosome abnormality associated with acute myeloid leukemia (AML). As a consequence of the translocation the AML1(CBFA2) gene in the 21q22 region is fused to the ETO(CDR,MTG8) gene...

A Hagemeijer, A de Klein, J Wijsman, E van Meerten, GE de Greef, N Sacchi in Leukemia (1998)

Article

Case-control study of oral cancer in Shenyang, Northeastern China

To investigate the risk factors of oral cancer, a hospital-based case-control study was conducted from March 1989 to September 1995 in Shenyang, Liaoning Province, China.

Wei-Zhong Su, Yoshiyuki Ohno, Iwai Tohnai… in International Journal of Clinical Oncology (1998)

Article

The modulating effect of PSC 833, cyclosporin A, verapamil and genistein on in vitro cytotoxicity and intracellular content of daunorubicin in childhood acute lymphoblastic leukemia

Resistance to anthracyclines is related to a poor prognosis in childhood acute lymphoblastic leukemia (ALL). Resistance to this class of drugs may (partly) be reversed by modulating agents, as has been demonst...

ML Den Boer, R Pieters, KM Kazemier, GE Janka-Schaub, G Henze, AJP Veerman in Leukemia (1998)

Article

Invasion and metastasis of liver cancer: expression of intercellular adhesion molecule 1

To study the relationship between intercellular adhesion molecule 1 (ICAM-1) and liver cancer metastasis and to find predicting factors that could indicate the growth and metastasis of liver cancer. Methods: ICA...

**g-**g Sun, **n-Da Zhou, Yin-Kun Liu… in Journal of Cancer Research and Clinical On… (1999)

Article

Cytogenetic studies of infant acute lymphoblastic leukemia: poor prognosis of infants with t(4;11) – a report of the Children’s Cancer Group

Infants less than 1 year of age at diagnosis of acute lymphoblastic leukemia (ALL) have a poor prognosis, which has been attributed primarily to a breakpoint in chromosomal band 11q23 or the MLL gene. Most infant...

NA Heerema, HN Sather, J Ge, DC Arthur, JM Hilden, ME Trigg, GH Reaman in Leukemia (1999)

Article

Analysis of aberrant methylation of the VHL gene by transgenes, monochromosome transfer, and cell fusion

Several tumor suppressor genes were shown to be inactivated by a process involving aberrant de novo methylation of their GC-rich promoters which is usually associated with transcriptional repression. The mechanis...

Igor Kuzmin, Laura Geil, Haiyan Ge, Ulla Bengtsson, Fuh-Mei Duh… in Oncogene (1999)

Article

Regulation of the Wilms' tumour suppressor protein transcriptional activation domain

The Wilms' tumour suppressor protein WT1 contains a transcriptional regulatory domain that can either activate or repress transcription depending upon its cellular environment. The mechanistic basis for this d...

Lynn M McKay, Brian Carpenter, Stefan GE Roberts in Oncogene (1999)

Article

Relationship between the intracellular daunorubicin concentration, expression of major vault protein/lung resistance protein and resistance to anthracyclines in childhood acute lymphoblastic leukemia

In vitro resistance to anthracyclines is related to a poor prognosis in childhood acute lymphoblastic leukemia (ALL), but the underlying mechanisms are poorly understood. Using flow cytometry, we studied the cont...

ML Den Boer, R Pieters, KM Kazemier, GE Janka-Schaub, G Henze, AJP Veerman in Leukemia (1999)

Article

Molecular dissection of TrkA signal transduction pathways mediating differentiation in human neuroblastoma cells

Activation of the neurotrophin receptor TrkA by its ligand nerve growth factor (NGF) initiates a cascade of signaling events leading to neuronal differentiation in vitro and might play an important role in the di...

Angelika Eggert, Naohiko Ikegaki, **ng-ge Liu, Thomas T Chou, Virginia M Lee… in Oncogene (2000)