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Clinical and functional consequences of GRIA variants in patients with neurological diseases

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  1. Article

    Open Access

    TRPM8 inhibits substance P release from primary sensory neurons via PKA/GSK-3beta to protect colonic epithelium in colitis

    Transient receptor potential melastatin 8 (TRPM8) is a cold sensory receptor in primary sensory neurons that regulates various neuronal functions. Substance P (SP) is a pro-inflammatory neuropeptide secreted b...

    Zehua Zhang, **aohan Yan, Le Kang, Zhuyun Leng, Yingjie Ji in Cell Death & Disease (2024)

  2. Article

    Open Access

    Identification of resistance loci in Chinese and Canadian canola/rapeseed varieties against Leptosphaeria maculans based on genome-wide association studies

    The fungal pathogen Leptosphaeria maculans (Lm). causes blackleg disease on canola/rapeseed in many parts of the world. It is important to use resistant cultivars to manage the disease and minimize yield losses. ...

    Fuyou Fu, Xuehua Zhang, Fei Liu, Gary Peng, Fengqun Yu, Dilantha Fernando in BMC Genomics (2020)

  3. Article

    Open Access

    Plant composition changes in a small-scale community have a large effect on the performance of an economically important grassland pest

    The grasshopper Oedaleus asiaticus Bey-Bienko (Acrididae: Oedipodinae) is a dominant and economically important pest that is widely distributed across the Mongolian plateau. This herbivore pest causes major damag...

    **nghu Qin, Huihui Wu, Xunbing Huang, T. Ryan Lock, Robert L. Kallenbach in BMC Ecology (2019)

  4. Article

    Open Access

    Comparative transcriptomic analysis of resistant and susceptible alfalfa cultivars (Medicago sativa L.) after thrips infestation

    Plant breeding for resistance to agricultural pests is an essential element in the development of integrated crop management systems; however, the molecular and genetic mechanisms underlying resistance are poo...

    **ongbing Tu, Zhongkuan Liu, Zehua Zhang in BMC Genomics (2018)

  5. Article

    Open Access

    Postzygotic single-nucleotide mosaicisms in whole-genome sequences of clinically unremarkable individuals

    Postzygotic single-nucleotide mutations (pSNMs) have been studied in cancer and a few other overgrowth human disorders at whole-genome scale and found to play critical roles. However, in clinically unremarkabl...

    August Y Huang, **ao**g Xu, Adam Y Ye, Qixi Wu, Linlin Yan, Boxun Zhao in Cell Research (2014)

  6. Article

    Open Access

    Analysis of the genomic sequence of Philosamia cynthia nucleopolyhedrin virus and comparison with Antheraea pernyinucleopolyhedrin virus

    Two species of wild silkworms, the Chinese oak silkworm (Antheraea pernyi) and the castor silkworm Philosamia cynthia ricini, can acquire a serious disease caused by Nucleopolyhedrin Viruses (NPVs) (known as Anpe...

    Heying Qian, Yuehua Zhang, Yejun Wu, **iang Sun, Shanying Zhu, **jie Guo in BMC Genomics (2013)