115 Result(s)
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Article
Nitric oxide-mediated apoptosis of K-1735 melanoma cells is associated with downregulation of Bcl-2
Recent studies have shown that the treatment of nonmetastatic K-1735 murine melanoma cells with cytokines induces the production of nitric oxide (NO) and hence cell death. The purpose of this study was to dete...
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Interactions of the Novel Antipsychotic Aripiprazole (OPC-14597) with Dopamine and Serotonin Receptor Subtypes
OPC-14597 {aripiprazole; 7-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyloxy)-3,4-dihydro-2(1H)-quinolinone} is a novel candidate antipsychotic that has high affinity for striatal dopamine D2-like receptors, but ...
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Article
p53 protects against skin cancer induction by UV-B radiation
To assess the role of the p53 tumor suppressor gene in skin carcinogenesis by UV radiation, mice constitutively lacking one or both copies of the functional p53 gene were compared to wild-type mice for their susc...
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Article
The basis of T-cell-mediated immunity to chronic myelogenous leukemia
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Article
Distortion product otoacoustic emissions in term infants after hypoxia-ischaemia
Distortion product otoacoustic emissions (DPOAEs) were recorded in 46 term infants who suffered perinatal hypoxia-ischaemia to identify which frequencies in the cochlear audiogram are susceptible to perinatal ...
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Article
Expression of MAGE-A1 mRNA is associated with gene hypomethylation in hepatocarcinoma cell lines
A correlation between melanoma-associated antigen (MAGE) A1 mRNA expression and genome-wide hypomethylation has been observed in some carcinomas, but this relationship is not known in hepatocarcinoma.
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Article
Synuclein Gamma Inhibits the Mitotic Checkpoint Function and Promotes Chromosomal Instability of Breast Cancer Cells
Aberrant expressions of the neuronal protein synuclein gamma (SNCG) in malignant mammary epithelial cells are strongly associated with the progression of breast cancer. SNCG is not expressed in normal breast t...
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Clinical study on concurrent and sequential therapy of intensity modulated radiation therapy (IMRT) combined with NP regimen chemotherapy in the treatment of middle and advanced non-small cell lung cancer
To evaluate the clinical effects of concurrent and sequential therapy for middle and advanced stage non-small cell lung cancer (NSCLC) useing IMRT combined with NP regimen chemotherapy.
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Article
Application of proton MR spectroscopy on evaluation of radiotherapy treated intracranial tumors
To evaluate the clinical application of proton magnetic resonance spectroscopy (1HMRS) in patients with radiotherapy treated intracranial tumors.
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Article
Distortion product otoacoustic emissions at 6 months in term infants after perinatal hypoxia-ischaemia or with a low Apgar score
Distortion product otoacoustic emissions (DPOAEs) were analyzed at 6 months of age in term infants who had perinatal hypoxia-ischaemia (HI) and those who had a low Agar score alone to detect any abnormalities ...
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Article
MRI signal changes in completely healed meniscus confirmed by second-look arthroscopy after meniscal repair with bioabsorbable arrows
This study evaluated the MRI signal characteristics and MRI diagnostic accuracy in identifying completely healed menisci repaired with bioabsorbable arrows. A total of 34 patients (38 menisci), with a mean age...
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Article
Changing Clostridium difficile infection testing and treatment trends at a large tertiary care teaching hospital
Objective To assess changes in testing and treatment trends of CDI at a time when the Clostridium difficile hypervirulent strain was first identified. Method A retrospective cohort study was performed. C. diffic...
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Article
Changes in BAER wave amplitudes in relation to total serum bilirubin level in term neonates
Whether the severity of bilirubin neurotoxicity is closely related to the level of total serum bilirubin (TSB) remains to be determined.
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Article
Variables affecting leakage past endotracheal tube cuffs: a bench study
Leakage of oral secretions past endotracheal tubes (ETT) has been implicated in ventilator associated pneumonia. The aim of this bench study was to compare the ability of current generation ETT cuffs to preven...
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Pathobiologic implications of methylation and expression status of Runx3 and CHFR genes in gastric cancer
Runx3 and CHFR genes were defined as tumor suppressor genes in gastric cancer (GC) recently. This paper was to investigate the roles of methylation and expression status of Runx3 and CHFR genes in GC patients....
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Article
Risk of genome-wide association study newly identified genetic variants for breast cancer in Chinese women of Heilongjiang Province
Recent genome-wide association studies have identified seven single nucleotide polymorphisms (SNPs) associated with breast cancer, but mainly in Europeans. In this study, the authors evaluated the effect of th...
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Clinical study on the recombinant human endostatin regarding improving the blood perfusion and hypoxia of non-small-cell lung cancer
To observe the dynamic changes of blood perfusion and hypoxic status with CT perfusion imaging and hypoxia imaging in patients of non-small-cell lung cancer (NSCLC) who were treated with recombinant human endo...
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Article
Preliminary clinical study of weekly recombinant human endostatin as a hypoxic tumour cell radiosensitiser combined with radiotherapy in the treatment of NSCLC
To investigate the clinical effects and adverse effects of weekly recombinant human endostatin (RHES) as a hypoxic tumour cell radiosensitiser combined with radiotherapy in the treatment of non-small-cell lung...
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Article
Identification of novel serological tumor markers for human prostate cancer using integrative transcriptome and proteome analysis
The aim of this study was to identify novel serological tumor markers for human prostate cancer (PCa). We compared the gene expression profile of PCa tissues to adjacent benign tissues of prostate using gene e...
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Neural conduction abnormality in the brain stem and prevalence of the abnormality in late preterm infants with perinatal problems
Neurodevelopment in late preterm infants has recently attracted considerable interest. The prevalence of brain stem conduction abnormality remains unknown. We examined maximum length sequence brain stem audito...
