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  1. No Access

    Article

    Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins

    We identify berberine (BBR), a compound isolated from a Chinese herb, as a new cholesterol-lowering drug. Oral administration of BBR in 32 hypercholesterolemic patients for 3 months reduced serum cholesterol b...

    Weijia Kong, **g Wei, Parveen Abidi, Meihong Lin, Satoru Inaba, Cong Li… in Nature Medicine (2004)

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    Article

    Robust tumor immunity to melanoma mediated by interleukin-9–producing T cells

    In this issue, Thomas Kupper and colleagues report that mice deficient for ROR-γ or interleukin-23 (IL-23) receptor showed impaired melanoma growth. Tumor growth inhibition was dependent in part on IL-9 and T ...

    Rahul Purwar, Christoph Schlapbach, Sheng **ao, Hong Soon Kang… in Nature Medicine (2012)

  3. Article

    Common clonal origin of central and resident memory T cells following skin immunization

    Following skin immunization a common naïve T cell precursor gives rise to resident and central memory T cells, which mediate rapid and delayed skin immune responses, respectively.

    Olivier Gaide, Ryan O Emerson, **aodong Jiang, Nicholas Gulati… in Nature Medicine (2015)

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    Article

    Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis

    We report the first case series of immune checkpoint inhibitors (ICI)-associated colitis successfully treated with fecal microbiota transplantation, with reconstitution of the gut microbiome and a relative inc...

    Yinghong Wang, Diana H. Wiesnoski, Beth A. Helmink… in Nature Medicine (2018)

  5. Article

    Author Correction: Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis

    In the version of this article originally published, an author was missing from the author list. Alexander J. Lazar should have been included between Jorge M. Blando and James P. Allison. The author has been a...

    Yinghong Wang, Diana H. Wiesnoski, Beth A. Helmink… in Nature Medicine (2019)

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    Article

    NDRG1 facilitates self-renewal of liver cancer stem cells by preventing EpCAM ubiquitination

    Portal vein tumour thrombus (PVTT) is the main pathway of HCC intrahepatic metastasis and is responsible for the poor prognosis of patients with HCC. However, the molecular mechanisms underlying PVTT vascular ...

    Qian Cheng, Shanglei Ning, Lei Zhu, Changlu Zhang… in British Journal of Cancer (2023)