3 Result(s)
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English
Life Sciences
Cell Biology
**axiang Li
Article
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Article
Open AccessOuabain prevents pathological cardiac hypertrophy and heart failure through activation of phosphoinositide 3-kinase α in mouse
Use of low doses of digitalis to prevent the development of heart failure was advocated decades ago, but conflicting results of early animal studies dissuaded further research on this issue. Recent discoverie...
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Article
The key players of parthanatos: opportunities for targeting multiple levels in the therapy of parthanatos-based pathogenesis
Parthanatos is a form of regulated cell death involved in the pathogenesis of many diseases, particularly neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease, Huntington’s disease, an...
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Article
Open AccessCryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state
The conserved ATPase p97 (Cdc48 in yeast) and adaptors mediate diverse cellular processes through unfolding polyubiquitinated proteins and extracting them from macromolecular assemblies and membranes for disag...
