Skip to main content

6 Result(s)

within English Remove this filter Neurology Remove this filter **aorui Yu Remove this filter Article Remove this filter

and

  1. No Access

    Article

    rhEPO Upregulates the PPARγ Pathway in Long-term Cultured Primary Nerve Cells via PI3K/Akt to Delay Cell Senescence

    Previous studies have confirmed that both recombinant human erythropoietin (rhEPO) and peroxisome proliferator-activated receptors γ (PPARγ) activator pioglitazone can protect senescent nerve cells, and their ...

    Huqing Wang, Ming Chen, Tao Zhang, Zhen Gao, Yu Gong… in Journal of Molecular Neuroscience (2022)

  2. No Access

    Article

    Inhibition of GSK-3β Activation Protects SD Rat Retina Against N-Methyl-N-Nitrosourea-Induced Degeneration by Modulating the Wnt/β-Catenin Signaling Pathway

    Retinal degenerative diseases are characterized by photoreceptor cell loss. Photoreceptor cell loss leading to retinal degeneration can be induced by N-methyl-N-nitrosourea (MNU), which was widely used to mimi...

    Baoying Wang, Chenghu Hu, **aobei Yang, Fangying Du… in Journal of Molecular Neuroscience (2017)

  3. No Access

    Article

    rhEPO Enhances Cellular Anti-oxidant Capacity to Protect Long-Term Cultured Aging Primary Nerve Cells

    Erythropoietin (EPO) may protect the nervous system of animals against aging damage, making it a potential anti-aging drug for the nervous system. However, experimental evidence from natural aging nerve cell mode...

    Huqing Wang, Jiaxin Fan, Mengyi Chen, Qingling Yao… in Journal of Molecular Neuroscience (2017)

  4. No Access

    Article

    17β-Estradiol Protects the Retinal Nerve Cells Suppressing TLR2 Mediated Immune-Inflammation and Apoptosis from Oxidative Stress Insult Independent of PI3K

    The excessive apoptosis of retinal nerve cells (RNCs) could cause a variety of retinal neurodegenerative diseases which could result in the irreversible blindness. In this study, the experiment models of H2O2 and...

    Hongbo Li, Chunhui Zhu, Baoying Wang, Wenhua Zhu… in Journal of Molecular Neuroscience (2016)

  5. No Access

    Article

    17β-Estradiol Ameliorates Light-Induced Retinal Damage in Sprague–Dawley Rats by Reducing Oxidative Stress

    Oxidative stress is considered as a major cause of light-induced retinal neurodegeneration. The protective role of 17β-estradiol (βE2) in neurodegenerative disorders is well known, but its underlying mechanism...

    Shaolan Wang, Baoying Wang, Yan Feng, Mingshu Mo… in Journal of Molecular Neuroscience (2015)

  6. No Access

    Article

    17β-Estradiol Impedes Bax-Involved Mitochondrial Apoptosis of Retinal Nerve Cells Induced by Oxidative Damage via the Phosphatidylinositol 3-Kinase/Akt Signal Pathway

    Oxidative stress leading to retinal nerve cells (RNCs) apoptosis is a major cause of neurodegenerative disorders of the retina. 17β-Estradiol (E2) has been suggested to be a neuroprotective agent in the centra...

    Hongbo Li, Baoying Wang, Chunhui Zhu, Yan Feng… in Journal of Molecular Neuroscience (2013)