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Article

Genetic editing and interrogation with Cpf1 and caged truncated pre-tRNA-like crRNA in mammalian cells

Cpf1, an RNA-guided DNA endonuclease that belongs to a new class II CRISPR system, has recently been harnessed for genome editing. Herein, we report an RNase-resistant caged truncated pre-tRNA-like crRNA (catR...

Xuhua Zhang, Lin** Xu, Ruihua Fan, Quanli Gao, Yunfeng Song… in Cell Discovery (2018)