5 Result(s)
within
Article
**aodong Feng
Biomedicine
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Article
Co-amorphous Drug Delivery Systems: a Review of Physical Stability, In Vitro and In Vivo Performance
Over the past few decades, co-amorphous solids have been used as a promising approach for delivering poorly water-soluble drugs. Co-amorphous solids, comprising pharmacologically relevant drug substances or ex...
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Article
Open AccessNLRP3 promotes tumor growth and metastasis in human oral squamous cell carcinoma
Inflammasomes are reported to be abnormally expressed and activated in several malignancies and play important roles in tumor development. The present study was designed to investigate the expression and funct...
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Article
Open AccessThe role of NLRP3 inflammasome in 5-fluorouracil resistance of oral squamous cell carcinoma
5-Fluorouracil (5-FU) is a widely used drug for the therapy of cancer. However, the chemoresistance of tumor cells to 5-FU usually limits its clinical effectiveness. In this study, we explored the role of NLRP...
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Article
Therapeutic Application of Pharmacogenomics in Oncology
Personalizing cancer treatment has been proved to be difficult for healthcare providers due to the nature of chemotherapies which includes narrow therapeutic indices, severe and potential life-threatening toxi...
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Article
Open AccessOverexpression of proteasomal activator PA28α serves as a prognostic factor in oral squamous cell carcinoma
Despite recent advances in oral squamous cell carcinoma (OSCC) diagnosis and therapy, disease recurrence remains common and is strongly associated with mortality. It is therefore critical to identify new targe...
