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Infusion of haploidentical HSCs combined with allogenic MSCs for the treatment of ALL patients

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  1. Article

    Open Access

    Radiomic signatures reveal multiscale intratumor heterogeneity associated with tissue tolerance and survival in re-irradiated nasopharyngeal carcinoma: a multicenter study

    Post-radiation nasopharyngeal necrosis (PRNN) is a severe adverse event following re-radiotherapy for patients with locally recurrent nasopharyngeal carcinoma (LRNPC) and associated with decreased survival. Bi...

    Ting Liu, Di Dong, Xun Zhao, **ao-Min Ou, Jun-Lin Yi, Jian Guan, Ye Zhang in BMC Medicine (2023)

  2. Article

    Open Access

    Metatranscriptome of human lung microbial communities in a cohort of mechanically ventilated COVID-19 Omicron patients

    The Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infected a substantial proportion of Chinese population, and understanding the factors underlying the severity of the dis...

    Lin Wang, Jia-Bao Cao, Bin-Bin **a, Yue-Juan Li in Signal Transduction and Targeted Therapy (2023)

  3. Article

    Open Access

    S1PR1 regulates ovarian cancer cell senescence through the PDK1-LATS1/2-YAP pathway

    Cell senescence deters the activation of various oncogenes. Induction of senescence is, therefore, a potentially effective strategy to interfere with vital processes in tumor cells. Sphingosine-1-phosphate rec...

    Yi-** Tao, Heng-Yan Zhu, Qian-Yuan Shi, Cai-**a Wang, Yu-**n Hua, Han-Yin Hu in Oncogene (2023)

  4. Article

    Open Access

    Divergent projections of the prelimbic cortex mediate autism- and anxiety-like behaviors

    The comorbidity of autism spectrum disorder and anxiety is common, but the underlying circuitry is poorly understood. Here, Tmem74-/- mice showed autism- and anxiety-like behaviors along with increased excitabili...

    Yi-Fan Luo, Lu Lu, Heng-Yi Song, Han Xu, Zhi-Wei Zheng, Zhou-Yue Wu in Molecular Psychiatry (2023)

  5. Article

    Open Access

    Erlotinib versus gemcitabine plus cisplatin as neoadjuvant treatment of stage IIIA-N2 EGFR-mutant non-small-cell lung cancer: final overall survival analysis of the EMERGING-CTONG 1103 randomised phase II trial

    EMERGING-CTONG 1103 showed improved progression-free survival (PFS) with neoadjuvant erlotinib vs. chemotherapy for patients harbouring EGFR sensibility mutations and R0 resected stage IIIA-N2 non-small cell l...

    Wen-Zhao Zhong, Hong-Hong Yan, Ke-Neng Chen in Signal Transduction and Targeted Therapy (2023)

  6. Article

    Hypertension Exacerbates Severity and Outcomes of COVID-19 in Elderly Patients: A Retrospective Observational Study

    To evaluate the impact of hypertension on the clinical outcome of COVID-19 patients aged 60 years old and older.

    Li-song Dai, Meng-pei Zhu, Yu-min Li, Hong-mei Zhou in Current Medical Science (2022)

  7. Article

    Open Access

    Safety and efficacy of meplazumab in healthy volunteers and COVID-19 patients: a randomized phase 1 and an exploratory phase 2 trial

    Recent evidence suggests that CD147 serves as a novel receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Blocking CD147 via anti-CD147 antibody could suppress the in vitro SAR...

    Huijie Bian, Zhao-Hui Zheng, Ding Wei in Signal Transduction and Targeted Therapy (2021)

  8. Article

    Open Access

    Glycemic control among patients in China with type 2 diabetes mellitus receiving oral drugs or injectables

    The prevalence of type 2 diabetes mellitus (T2DM) is increasing rapidly among Chinese adults, and limited data are available on T2DM management and the status of glycemic control in China. We assessed the effi...

    Li-Nong Ji, Ju-Ming Lu, **ao-Hui Guo, Wen-Ying Yang, Jian-** Weng in BMC Public Health (2013)