9 Result(s)

Article

Metatranscriptome of human lung microbial communities in a cohort of mechanically ventilated COVID-19 Omicron patients

The Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infected a substantial proportion of Chinese population, and understanding the factors underlying the severity of the dis...

Lin Wang, Jia-Bao Cao, Bin-Bin **a, Yue-Juan Li… in Signal Transduction and Targeted Therapy (2023)

Article

S1PR1 regulates ovarian cancer cell senescence through the PDK1-LATS1/2-YAP pathway

Cell senescence deters the activation of various oncogenes. Induction of senescence is, therefore, a potentially effective strategy to interfere with vital processes in tumor cells. Sphingosine-1-phosphate rec...

Yi-** Tao, Heng-Yan Zhu, Qian-Yuan Shi, Cai-**a Wang, Yu-**n Hua, Han-Yin Hu… in Oncogene (2023)

Article

Erlotinib versus gemcitabine plus cisplatin as neoadjuvant treatment of stage IIIA-N2 EGFR-mutant non-small-cell lung cancer: final overall survival analysis of the EMERGING-CTONG 1103 randomised phase II trial

EMERGING-CTONG 1103 showed improved progression-free survival (PFS) with neoadjuvant erlotinib vs. chemotherapy for patients harbouring EGFR sensibility mutations and R0 resected stage IIIA-N2 non-small cell l...

Wen-Zhao Zhong, Hong-Hong Yan, Ke-Neng Chen… in Signal Transduction and Targeted Therapy (2023)

Article

Correction to: Associations of combined healthy lifestyles with cancer morbidity and mortality among individuals with diabetes: results from five cohort studies in the USA, the UK and China

Yan-Bo Zhang, **ong-Fei Pan, Qi Lu, Yan-**u Wang, Ting-Ting Geng… in Diabetologia (2022)

Article

Associations of combined healthy lifestyles with cancer morbidity and mortality among individuals with diabetes: results from five cohort studies in the USA, the UK and China

Cancer has contributed to an increasing proportion of diabetes-related deaths, while lifestyle management is the cornerstone of both diabetes care and cancer prevention. We aimed to evaluate the associations o...

Yan-Bo Zhang, **ong-Fei Pan, Qi Lu, Yan-**u Wang, Ting-Ting Geng… in Diabetologia (2022)

Article

Safety and efficacy of meplazumab in healthy volunteers and COVID-19 patients: a randomized phase 1 and an exploratory phase 2 trial

Recent evidence suggests that CD147 serves as a novel receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Blocking CD147 via anti-CD147 antibody could suppress the in vitro SAR...

Huijie Bian, Zhao-Hui Zheng, Ding Wei… in Signal Transduction and Targeted Therapy (2021)

Article

Rhomboid intercostal block combined with sub-serratus plane block versus rhomboid intercostal block for postoperative analgesia after video-assisted thoracoscopic surgery: a prospective randomized-controlled trial

Rhomboid intercostal block (RIB) and Rhomboid intercostal block with sub-serratus plane block (RISS) are the two types of plane blocks used for postoperative analgesia after video-assisted thoracoscopic surger...

Wei Deng, **ao-min Hou, Xu-yan Zhou, Qing-he Zhou in BMC Pulmonary Medicine (2021)

Article

A de novo SCN8A heterozygous mutation in a child with epileptic encephalopathy: a case report

Epilepsy is a complex disorder caused by various factors, including genetic aberrance. Recent studies have identified an essential role of the sodium channel Nav1.6, encoded by the gene SCN8A, in epileptic enceph...

Kao-Min Lin, Geng Su, Fengpeng Wang, **aobin Zhang, Yuanqing Wang… in BMC Pediatrics (2019)

Article

Evaluation of the chemical composition of nephrolithiasis using dual-energy CT in Southern Chinese gout patients

A study to evaluate the prevalence of uric acid (UA) nephrolithiasis with dual-energy CT (DECT) and explore the risk factors for kidney stones in primary gout patients.

Zhao-**a Li, Gen-Long Jiao, Shu-Min Zhou, Zhong Yuan Cheng, Shoaib Bashir… in BMC Nephrology (2019)