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Human Bcl-2 activates ERK signaling pathway to regulate activating protein-1, lens epithelium-derived growth factor and downstream genes

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  1. Article

    Open Access

    Poor cardiovascular health status among Chinese women

    Systematic investigation and analysis of cardiovascular health status (CVHS) of Chinese women is rare. This study aimed to assess CVHS and atherosclerotic cardiovascular disease (ASCVD) burden in the Chinese w...

    Tian-Wen Han, Yu-Qi Liu, Wei Dong, **ao-Juan Bai in BMC Cardiovascular Disorders (2020)

  2. Article

    Open Access

    Reprogramming immunosuppressive myeloid cells by activated T cells promotes the response to anti-PD-1 therapy in colorectal cancer

    Overcoming local immunosuppression is critical for immunotherapy to produce robust anti-tumor responses. Myeloid-derived suppressor cells (MDSCs) are key regulators of immunosuppressive networks and promote tu...

    **g Chen, Hong-Wei Sun, Yan-Yan Yang in Signal Transduction and Targeted Therapy (2021)

  3. Article

    Open Access

    Sulfated alginate oligosaccharide exerts antitumor activity and autophagy induction by inactivating MEK1/ERK/mTOR signaling in a KSR1-dependent manner in osteosarcoma

    Alginate oligosaccharide (AOS) has the function to inhibit tumor progression and the sulfated modification can enhance the antitumor activity. To date, the function and mechanism of sulfated AOS (AOS-SO4) in tumo...

    Zhen Pan, **ao-juan Wei, Shi-jie Li, Hua Guo, Zhao-hui Li, Ke-ke Zhang in Oncogenesis (2022)

  4. Article

    Open Access

    Inhibition of USP1 reverses the chemotherapy resistance through destabilization of MAX in the relapsed/refractory B-cell lymphoma

    The patients with relapsed and refractory diffuse large B-cell lymphoma (DLBCL) have poor prognosis, and a novel and effective therapeutic strategy for these patients is urgently needed. Although ubiquitin-spe...

    **-Ya Li, Ji-Chuan Wu, ** Liu, Zi-Juan Li, Yong Wang, Bing-Yi Chen in Leukemia (2023)

  5. Article

    Open Access

    Anti-complement factor H (CFH) autoantibodies could delay pristane-induced lupus nephritis

    Anti-complement factor H (CFH) autoantibodies could be detected in lupus and its significance remained to be elucidated. Herein, we aimed to explore the roles of anti-CFH autoantibodies based on pristane-induc...

    Lin-Lin Li, Zhong-qiu Luan, Ying Tan, Hui Wang, **ao-Juan Yu in Immunologic Research (2023)

  6. Article

    Open Access

    Hemothorax caused by injury of musculophrenic artery after ultrasound-guided percutaneous liver biopsy: a case report

    Hemorrhage is the most common major complication after liver biopsy. Hemothorax is one type of bleeding and is very rare and dangerous. Several cases of hemothorax subsequent to liver biopsy have been document...

    **g-ru Yang, Sai Wu, Jian Li, **ao-juan Tian in Journal of Medical Case Reports (2024)