20 Result(s)

Article

Co-expression of nuclear and cytoplasmic HMGB1 is inversely associated with infiltration of CD45RO+ T cells and prognosis in patients with stage IIIB colon cancer

The intratumoral infiltration of T cells, especially memory T cells, is associated with a favorable prognosis in early colorectal cancers. However, the mechanism underlying this process remains elusive. This s...

Rui-Qing Peng, **ao-Jun Wu, Ya Ding, Chun-Yan Li, **ng-Juan Yu, **ng Zhang… in BMC Cancer (2010)

Article

Erratum to: Autophagy precedes apoptosis during the remodeling of silkworm larval midgut

Eleonora Franzetti, Zhi-Jun Huang, Yan-**a Shi, Kun **e, **ao-Juan Deng… in Apoptosis (2012)

Article

Lycorine induces cell-cycle arrest in the G0/G1 phase in K562 cells via HDAC inhibition

Lycorine, a natural alkaloid extracted from Amaryllidaceae, has shown various pharmacological effects. Recent studies have focused on the potential antitumor activity of lycorine. In our previous study, we found ...

Lv Li, Hong-Juan Dai, Mao Ye, Shu-Ling Wang, **ao-Juan **ao… in Cancer Cell International (2012)

Article

Survivin selective inhibitor YM155 induce apoptosis in SK-NEP-1 Wilms tumor cells

Survivin, a member of the family of inhibitor of apoptosis proteins, functions as a key regulator of mitosis and programmed cell death. YM155, a novel molecular targeted agent, suppresses survivin, which is ov...

Yan-Fang Tao, Jun Lu, **ao-Juan Du, Li-Chao Sun, Xuan Zhao, Liang Peng… in BMC Cancer (2012)

Article

A TrkB–STAT3–miR-204-5p regulatory circuitry controls proliferation and invasion of endometrial carcinoma cells

We previously identified TrkB as an oncogene involved in promoting metastasis in endometrial carcinoma (EC). Here, we sought to delineate the effect of changes in TrkB expression on the global profile of micro...

Wei Bao, Hui-Hui Wang, Fu-Ju Tian, **ao-Ying He, Mei-Ting Qiu… in Molecular Cancer (2013)

Article

Early B-cell factor 3 (EBF3) is a novel tumor suppressor gene with promoter hypermethylation in pediatric acute myeloid leukemia

Pediatric acute myeloid leukemia (AML) comprises up to 20% of all childhood leukemia. Recent research shows that aberrant DNA methylation patterning may play a role in leukemogenesis. The epigenetic silencing ...

Yan-Fang Tao, Li-**ao Xu, Jun Lu… in Journal of Experimental & Clinical Cancer … (2015)

Article

Analyzing the gene expression profile of anaplastic histology Wilms’ tumor with real-time polymerase chain reaction arrays

Wilms’ tumor (WT) is one of the most common malignant neoplasms of the urinary tract in children. Anaplastic histology (unfavorable histology) accounts for about 10% of whole WTs, and it is the single most imp...

Jun Lu, Yan-Fang Tao, Zhi-Heng Li, Lan Cao, Shao-Yan Hu… in Cancer Cell International (2015)

Article

Hypermethylation of the GATA binding protein 4 (GATA4) promoter in Chinese pediatric acute myeloid leukemia

Acute myeloid leukemia (AML) is the second-most common form of leukemia in children. Aberrant DNA methylation patterns are a characteristic feature of AML. GATA4 has been suggested to be a tumor suppressor gen...

Yan-Fang Tao, Fang Fang, Shao-Yan Hu, Jun Lu, Lan Cao, Wen-Li Zhao… in BMC Cancer (2015)

Article

DNMT3A mutation leads to leukemic extramedullary infiltration mediated by TWIST1

DNMT3A mutations are frequently discovered in acute myeloid leukemia (AML), associated with poor outcome. Recently, a relapse case report of AML extramedullary disease has showed that ...

Jie Xu, Wu Zhang, **ao-**g Yan, Xue-Qiu Lin, Wei Li… in Journal of Hematology & Oncology (2016)

Article

miR-10b exerts oncogenic activity in human hepatocellular carcinoma cells by targeting expression of CUB and sushi multiple domains 1 (CSMD1)

Hepatocellular carcinoma (HCC) is a lethal disease, while the precise underlying molecular mechanisms of HCC pathogenesis remain to be defined. MicroRNA (miRNA), a class of non-coding small RNAs, can post-tran...

Qiao Zhu, Li Gong, Jun Wang, Qian Tu, Li Yao, Jia-Rui Zhang, **u-Juan Han… in BMC Cancer (2016)

Article

Californium-252 neutron brachytherapy combined with external pelvic radiotherapy plus concurrent chemotherapy for cervical cancer: a retrospective clinical study

Cervical cancer is the sixth most common cancer in Chinese women. A standard treatment modality for cervical cancer is the combination of surgery, chemotherapy, external-beam radiotherapy and intracavitary bra...

Shen Qian, Ling Ye, Yun-Hong Tian, Li-Gen Wang, Zuo-** Huang… in Chinese Journal of Cancer (2017)

Article

Expression patterns of programmed death ligand 1 correlate with different microenvironments and patient prognosis in hepatocellular carcinoma

Recent clinical studies have suggested that programmed death ligand 1 (PD-L1) expression in a tumour could be a potential biomarker for PD-L1/PD-1 blockade therapies.

Chao-Qun Liu, **g Xu, Zhong-Guo Zhou, Li-Lian **… in British Journal of Cancer (2018)

Article

LncRNA ANRIL regulates AML development through modulating the glucose metabolism pathway of AdipoR1/AMPK/SIRT1

The long noncoding RNA ANRIL has been found to be abnormally expressed and play important roles in different cancers. However, the expression and function of ANRIL in acute myeloid leukemia (AML) remain to be ...

Lin-Yu Sun, **ao-Juan Li, Yu-Meng Sun, Wei Huang, Ke Fang, Cai Han… in Molecular Cancer (2018)

Article

Antibody responses to SARS-CoV-2 in patients with COVID-19

We report acute antibody responses to SARS-CoV-2 in 285 patients with COVID-19. Within 19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G (IgG). Seroconversion for IgG...

Quan-**n Long, Bai-Zhong Liu, Hai-Jun Deng, Gui-Cheng Wu, Kun Deng… in Nature Medicine (2020)

Article

Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections

The clinical features and immune responses of asymptomatic individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have not been well described. We studied 37 asymptomatic indivi...

Quan-**n Long, **ao-Jun Tang, Qiu-Lin Shi, Qin Li, Hai-Jun Deng… in Nature Medicine (2020)

Article

Reprogramming immunosuppressive myeloid cells by activated T cells promotes the response to anti-PD-1 therapy in colorectal cancer

Overcoming local immunosuppression is critical for immunotherapy to produce robust anti-tumor responses. Myeloid-derived suppressor cells (MDSCs) are key regulators of immunosuppressive networks and promote tu...

**g Chen, Hong-Wei Sun, Yan-Yan Yang… in Signal Transduction and Targeted Therapy (2021)

Article

A novel prognostic index for sporadic Burkitt lymphoma in adult patients: a real-word multicenter study

Adult sporadic Burkitt lymphoma (BL) is a rare but highly aggressive subtype of lymphoma which lacks its own unique prognostic model. Systemic inflammatory biomarkers have been confirmed as prognostic markers ...

Mei-ting Chen, Fei Pan, Yung-chang Chen, Wei Zhang, Hui-juan Lv, Zhao Wang… in BMC Cancer (2022)

Article

Quantification of fibrinogen-to-pre-albumin ratio provides an integrating parameter for differential diagnosis and risk stratification of early-stage colorectal cancer

Circulating fibrinogen to pre-albumin ratio (FPR) and albumin to fibrinogen ratio (AFR) are effective factors for predicting the prognosis of colorectal cancer (CRC). However, the role of these two ratios in d...

Hou-Qun Ying, Wei Chen, Cui-Fen **ong, Yuanyuan Wang… in Cancer Cell International (2022)

Article

Inhibition of USP1 reverses the chemotherapy resistance through destabilization of MAX in the relapsed/refractory B-cell lymphoma

The patients with relapsed and refractory diffuse large B-cell lymphoma (DLBCL) have poor prognosis, and a novel and effective therapeutic strategy for these patients is urgently needed. Although ubiquitin-spe...

**-Ya Li, Ji-Chuan Wu, ** Liu, Zi-Juan Li, Yong Wang, Bing-Yi Chen… in Leukemia (2023)

Article

Exosomal hsa_circ_000200 as a potential biomarker and metastasis enhancer of gastric cancer via miR-4659a/b-3p/HBEGF axis

Exosome, a component of liquid biopsy, loaded protein, DNA, RNA and lipid gradually emerges as biomarker in tumors. However, exosomal circRNAs as biomarker and function mechanism in gastric cancer (GC) are not...

**ao-juan Huang, Yan Wang, Hui-ting Wang, Zhao-feng Liang… in Cancer Cell International (2023)