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Article
Matrix compatibility of typical sol–gel solid-phase microextraction coatings in undiluted plasma and whole blood for the analysis of phthalic acid esters
Sol–gel materials have been widely used for solid-phase microextraction (SPME) coatings due to their outstanding performance; in contrast, sol–gel SPME coatings have seldom been used for in vivo sampling. The ...
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Article
Open AccessA comprehensive review on microbial production of 1,2-propanediol: micro-organisms, metabolic pathways, and metabolic engineering
1,2-Propanediol is an important building block as a component used in the manufacture of unsaturated polyester resin, antifreeze, biofuel, nonionic detergent, etc. Commercial production of 1,2-propanediol thro...
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Article
Open AccessDirected evolution of a β-mannanase from Rhizomucor miehei to improve catalytic activity in acidic and thermophilic conditions
β-Mannanase randomly cleaves the β-1,4-linked mannan backbone of hemicellulose, which plays the most important role in the enzymatic degradation of mannan. Although the industrial applications of β-mannanase h...
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Article
Open AccessThe octanol/water distribution coefficients of ardipusilloside-I and its metabolites, and their permeation characteristics across Caco-2 cell monolayer
Ardipusilloside-I (ADS-I) is a triterpenoid saponin extracted from Chinese medicinal herb Ardisiapusill A. DC. Previous studies have demonstrated the potent anti-tumor activities of ADS-I both in vitro and in viv...