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Inhibition of PPP1R15A alleviates osteoporosis via suppressing RANKL-induced osteoclastogenesis

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  1. Article

    Open Access

    Deficiency of leucine-rich repeat kinase 2 aggravates thioacetamide-induced acute liver failure and hepatic encephalopathy in mice

    Hepatic encephalopathy (HE) is closely associated with inflammatory responses. However, as a crucial regulator of the immune and inflammatory responses, the role of leucine-rich repeat kinase 2 (LRRK2) in the ...

    Dan Li, Shu-fang Yu, Lin Lin, Jie-ru Guo, Si-mei Huang in Journal of Neuroinflammation (2024)

  2. Article

    Author Correction: Pharmacokinetics, mass balance, and metabolism of [14C]vicagrel, a novel irreversible P2Y12 inhibitor in humans

    Yuan-dong Zheng, Hua Zhang, Yan Zhan, Yi-cong Bian, Sheng Ma in Acta Pharmacologica Sinica (2023)

  3. Article

    Open Access

    Anti-complement factor H (CFH) autoantibodies could delay pristane-induced lupus nephritis

    Anti-complement factor H (CFH) autoantibodies could be detected in lupus and its significance remained to be elucidated. Herein, we aimed to explore the roles of anti-CFH autoantibodies based on pristane-induc...

    Lin-Lin Li, Zhong-qiu Luan, Ying Tan, Hui Wang, **ao-Juan Yu in Immunologic Research (2023)

  4. Article

    Open Access

    Optimized strategy for schistosomiasis elimination: results from marginal benefit modeling

    Poverty contributes to the transmission of schistosomiasis via multiple pathways, with the insufficiency of appropriate interventions being a crucial factor. The aim of this article is to provide more economic...

    Qin Li, **-**n Zheng, Tie-Wu Jia, **n-Yu Feng, Chao Lv in Parasites & Vectors (2023)

  5. Article

    Open Access

    Exosomal hsa_circ_000200 as a potential biomarker and metastasis enhancer of gastric cancer via miR-4659a/b-3p/HBEGF axis

    Exosome, a component of liquid biopsy, loaded protein, DNA, RNA and lipid gradually emerges as biomarker in tumors. However, exosomal circRNAs as biomarker and function mechanism in gastric cancer (GC) are not...

    **ao-juan Huang, Yan Wang, Hui-ting Wang, Zhao-feng Liang in Cancer Cell International (2023)

  6. Article

    Open Access

    High risk of bloodstream infection of carbapenem-resistant enterobacteriaceae carriers in neutropenic children with hematological diseases

    Neutropenic children with hematological diseases were associated with higher morbidity of carbapenem-resistant enterobacteriaceae (CRE) blood-stream infection (BSI) or colonization. But it was still murky rega...

    Li-Peng Liu, Qing-Song Lin, Wen-Yu Yang in Antimicrobial Resistance & Infection Contr… (2023)

  7. Article

    Open Access

    The spatiotemporal matching pattern of Ezrin/Periaxin involved in myoblast differentiation and fusion and Charcot-Marie-Tooth disease-associated muscle atrophy

    Clinically, Charcot-Marie-Tooth disease (CMT)-associated muscle atrophy still lacks effective treatment. Deletion and mutation of L-periaxin can be involved in CMT type 4F (CMT4F) by destroying the myelin shea...

    Ruo-nan Zhang, **n Bao, Yun Liu, Yan Wang in Journal of Translational Medicine (2023)

  8. Article

    Correction to: Matrine Treatment Blocks NogoA-Induced Neural Inhibitory Signaling Pathway in Ongoing Experimental Autoimmune Encephalomyelitis

    Quan-Cheng Kan, Hui-Jun Zhang, Yuan Zhang, **ng Li, Yu-Ming Xu in Molecular Neurobiology (2022)

  9. Article

    Open Access

    Quantification of fibrinogen-to-pre-albumin ratio provides an integrating parameter for differential diagnosis and risk stratification of early-stage colorectal cancer

    Circulating fibrinogen to pre-albumin ratio (FPR) and albumin to fibrinogen ratio (AFR) are effective factors for predicting the prognosis of colorectal cancer (CRC). However, the role of these two ratios in d...

    Hou-Qun Ying, Wei Chen, Cui-Fen **ong, Yuanyuan Wang in Cancer Cell International (2022)

  10. Article

    Open Access

    A novel prognostic index for sporadic Burkitt lymphoma in adult patients: a real-word multicenter study

    Adult sporadic Burkitt lymphoma (BL) is a rare but highly aggressive subtype of lymphoma which lacks its own unique prognostic model. Systemic inflammatory biomarkers have been confirmed as prognostic markers ...

    Mei-ting Chen, Fei Pan, Yung-chang Chen, Wei Zhang, Hui-juan Lv, Zhao Wang in BMC Cancer (2022)

  11. Article

    Correction to: Central Blockade of E-Prostanoid 3 Receptor Ameliorated Hypertension Partially by Attenuating Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus of Spontaneously Hypertensive Rats

    The original version of this article unfortunately contained a mistake in the name of one co-author. The correct name of the co-author “Juan Ba” should be “Juan Bai”.

    Fang-Fang Wang, Juan Bai, **ao-**g Yu, **ao-Lian Shi in Cardiovascular Toxicology (2021)

  12. Article

    Open Access

    A Novel PCR Method for Detecting ACE Gene Insertion/Deletion Polymorphisms and its Clinical Application

    Angiotensin-converting enzyme (ACE) plays a major role in blood pressure regulation and cardiovascular homeostasis. The wide distribution and multifunctional properties of ACE suggest it’s involvement in vario...

    Xue-min Yang, Jian-** Liang, **ao-juan Huang in Biological Procedures Online (2021)

  13. Article

    Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections

    The clinical features and immune responses of asymptomatic individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have not been well described. We studied 37 asymptomatic indivi...

    Quan-**n Long, **ao-Jun Tang, Qiu-Lin Shi, Qin Li, Hai-Jun Deng in Nature Medicine (2020)

  14. Article

    Antibody responses to SARS-CoV-2 in patients with COVID-19

    We report acute antibody responses to SARS-CoV-2 in 285 patients with COVID-19. Within 19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G (IgG). Seroconversion for IgG...

    Quan-**n Long, Bai-Zhong Liu, Hai-Jun Deng, Gui-Cheng Wu, Kun Deng in Nature Medicine (2020)

  15. Article

    Open Access

    Thioredoxin peroxidase secreted by Echinococcus granulosus (sensu stricto) promotes the alternative activation of macrophages via PI3K/AKT/mTOR pathway

    Larvae of Echinococcus granulosus (sensu lato) dwell in host organs for a long time but elicit only a mild inflammatory response, which indicates that the resolution of host inflammation is necessary for parasite...

    Hui Wang, Chuan-Shan Zhang, Bin-Bin Fang, Zhi-De Li, Liang Li in Parasites & Vectors (2019)

  16. Article

    Pathogenicity of an FAdV-4 isolate to chickens and its genomic analysis

    Fowl adenovirus serotype 4 (FAdV-4) strain SD1511 was isolated from chickens with severe inclusion body hepatitis and hydropericardium syndrome in Shandong Province, China. The isolate was cultured in primary ...

    Kai-kun Mo, Chen-fei Lyu, Shang-shang Cao in Journal of Zhejiang University-SCIENCE B (2019)

  17. Article

    Open Access

    The spleen may be an important target of stem cell therapy for stroke

    Stroke is the most common cerebrovascular disease, the second leading cause of death behind heart disease and is a major cause of long-term disability worldwide. Currently, systemic immunomodulatory therapy ba...

    Zhe Wang, Da He, Ya-Yue Zeng, Li Zhu, Chao Yang in Journal of Neuroinflammation (2019)

  18. Article

    Open Access

    LncRNA ANRIL regulates AML development through modulating the glucose metabolism pathway of AdipoR1/AMPK/SIRT1

    The long noncoding RNA ANRIL has been found to be abnormally expressed and play important roles in different cancers. However, the expression and function of ANRIL in acute myeloid leukemia (AML) remain to be ...

    Lin-Yu Sun, **ao-Juan Li, Yu-Meng Sun, Wei Huang, Ke Fang, Cai Han in Molecular Cancer (2018)

  19. Article

    Open Access

    Expression patterns of programmed death ligand 1 correlate with different microenvironments and patient prognosis in hepatocellular carcinoma

    Recent clinical studies have suggested that programmed death ligand 1 (PD-L1) expression in a tumour could be a potential biomarker for PD-L1/PD-1 blockade therapies.

    Chao-Qun Liu, **g Xu, Zhong-Guo Zhou, Li-Lian ** in British Journal of Cancer (2018)

  20. Article

    Erratum to: Matrine Treatment Blocks NogoA-Induced Neural Inhibitory Signaling Pathway in Ongoing Experimental Autoimmune Encephalomyelitis

    Quan-Cheng Kan, Hui-Jun Zhang, Yuan Zhang, **ng Li, Yu-Ming Xu in Molecular Neurobiology (2017)

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