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  1. Article

    Open Access

    Mitochondrial oxidative stress in aging and healthspan

    The free radical theory of aging proposes that reactive oxygen species (ROS)-induced accumulation of damage to cellular macromolecules is a primary driving force of aging and a major determinant of lifespan. A...

    Dao-Fu Dai, Ying Ann Chiao, David J Marcinek, Hazel H Szeto… in Longevity & Healthspan (2014)

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  2. Article

    Open Access

    Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial

    It’s a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in the differentiated populations with complex diseases, as stable coronary heart ...

    Jun Liu, Dan-Dan Li, Wei Dong, Yu-Qi Liu… in Signal Transduction and Targeted Therapy (2021)

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  3. Article

    Open Access

    Anti-metabolic agent pegaspargase plus PD-1 antibody sintilimab for first-line treatment in advanced natural killer T cell lymphoma

    Natural killer T cell lymphoma (NKTCL) is highly aggressive, with advanced stage patients poorly responding to intensive chemotherapy. To explore effective and safe treatment for newly diagnosed advanced stage...

    Jie **ong, Shu Cheng, **ao Gao, Shan-He Yu… in Signal Transduction and Targeted Therapy (2024)

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