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    Raloxifene inhibits bone loss and improves bone strength through an Opg-independent mechanism

    The osteoblast-derived paracrine factor osteoprotegerin (OPG) is considered to play a key role in inhibition of osteoclast formation and activity. Recently, raloxifene, a nonsteroidal benzothiophene, was found...

    Mei-zhu Yan, Yong Xu, Yun-xia Gong, Jian-min Liu, Shun-yuan Lu, Lei Huang in Endocrine (2010)