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  1. No Access

    Article

    Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies a susceptibility locus at PLCE1

    Li Dong Wang and colleagues report a genome wide association study for esophageal squamous cell carcinoma in the Chinese population. They identify two risk loci at PLCE1 and C20orf54.

    Li-Dong Wang, Fu-You Zhou, Xue-Min Li, Liang-Dan Sun, **n Song, Yan **… in Nature Genetics (2010)

  2. No Access

    Article

    Association analyses identify six new psoriasis susceptibility loci in the Chinese population

    Xue-Jun Zhang and colleagues report genome-wide association analyses identifying six new susceptibility loci in the Chinese population.

    Liang-Dan Sun, Hui Cheng, Zai-**ng Wang, An-** Zhang, Pei-Guang Wang… in Nature Genetics (2010)

  3. No Access

    Article

    Genome-wide association study identifies two new susceptibility loci for atopic dermatitis in the Chinese Han population

    Xue-Jun Zhang, Zhi-Rong Yao and colleagues report a genome-wide association study for atopic dermatitis in the Chinese Han population. They identified two new susceptibility loci at 5q22 and 20q13.

    Liang-Dan Sun, Feng-Li **ao, Yang Li, Wen-Ming Zhou, Hua-Yang Tang… in Nature Genetics (2011)

  4. No Access

    Article

    Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

    Qing Lan and colleagues report the results of a genome-wide association study of lung cancer in never-smoking women from Asia. They identify three new susceptibility loci and confirm three other previously rep...

    Qing Lan, Chao A Hsiung, Keitaro Matsuo, Yun-Chul Hong, Adeline Seow… in Nature Genetics (2012)

  5. Article

    Corrigendum: Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54

    Nat. Genet. 42, 759–763 (2010); published online 22 August 2010; corrected after print 27 August 2014 In contrast to the version of this article initially published, the authors now find no evidence to support...

    Li-Dong Wang, Fu-You Zhou, Xue-Min Li, Liang-Dan Sun, **n Song, Yan **… in Nature Genetics (2014)

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  6. No Access

    Article

    Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations

    Dongxin Lin, Philip Taylor, Li-Dong Wang and colleagues have now pooled three genome-wide association analyses of esophageal squamous cell carcinoma, finding two new risk loci at genome-wide significance and a...

    Chen Wu, Zhaoming Wang, **n Song, **ao-Shan Feng, Christian C Abnet… in Nature Genetics (2014)

  7. No Access

    Article

    JMJD6 regulates histone H2A.X phosphorylation and promotes autophagy in triple-negative breast cancer cells via a novel tyrosine kinase activity

    Overexpression of Jumonji domain-containing 6 (JMJD6) has been reported to be associated with more aggressive breast cancer characteristics. However, the precise role of JMJD6 in breast cancer development rema...

    Yan Liu, Yue-Hong Long, Shu-Qing Wang, Yuan-Yue Zhang, Yu-Feng Li… in Oncogene (2019)

  8. No Access

    Article

    Fine-map** of 150 breast cancer risk regions identifies 191 likely target genes

    Genome-wide association studies have identified breast cancer risk variants in over 150 genomic regions, but the mechanisms underlying risk remain largely unknown. These regions were explored by combining asso...

    Laura Fachal, Hugues Aschard, Jonathan Beesley, Daniel R. Barnes… in Nature Genetics (2020)

  9. Article

    Open Access

    CEOP/IVE/GDP alternating regimen compared with CEOP as the first-line therapy for newly diagnosed patients with peripheral T cell lymphoma: results from a phase 2, multicenter, randomized, controlled clinical trial

    Cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP)/CHOP-like chemotherapy is widely used in peripheral T cell lymphoma (PTCL). Here we conducted a phase 2, multicenter, randomized, controlled ...

    Ming-Ci Cai, Shu Cheng, **n Wang, Jian-Da Hu, Yong-** Song… in Genome Medicine (2020)

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  10. No Access

    Article

    WSTF acetylation by MOF promotes WSTF activities and oncogenic functions

    Williams syndrome transcription factor (WSTF) is a transcription factor and tyrosine kinase. WSTF overexpression promotes migration and proliferation of various cancers, and Ser158 (WSTFS158) phosphorylation play...

    Yan Liu, Yuan-Yue Zhang, Shu-Qing Wang, Min Li, Yue-Hong Long, Yu-Feng Li… in Oncogene (2020)

  11. No Access

    Article

    Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

    We assembled an ancestrally diverse collection of genome-wide association studies (GWAS) of type 2 diabetes (T2D) in 180,834 affected individuals and 1,159,055 controls (48.9% non-European descent) through the...

    Anubha Mahajan, Cassandra N. Spracklen, Weihua Zhang, Maggie C. Y. Ng… in Nature Genetics (2022)