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Prenatal glucocorticoid contributed to rat lung dysplasia is related to asymmetric dimethylarginine/nitric oxide pathway

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  1. Article

    Open Access

    GLP-1 receptor agonists’ impact on cardio-renal outcomes and mortality in T2D with acute kidney disease

    Previous studies have explored the effects of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in reducing cardiovascular events in type 2 diabetes. Here we show that GLP-1 RAs are associated with lower r...

    Heng-Chih Pan, Jui-Yi Chen, Hsing-Yu Chen, Fang-Yu Yeh in Nature Communications (2024)

  2. Article

    Open Access

    High-efficiency reinforcement learning with hybrid architecture photonic integrated circuit

    Reinforcement learning (RL) stands as one of the three fundamental paradigms within machine learning and has made a substantial leap to build general-purpose learning systems. However, using traditional electr...

    Xuan-Kun Li, Jian-Xu Ma, **ang-Yu Li, Jun-Jie Hu, Chuan-Yang Ding in Nature Communications (2024)

  3. Article

    Open Access

    Maternal dominance contributes to subgenome differentiation in allopolyploid fishes

    Teleost fishes, which are the largest and most diverse group of living vertebrates, have a rich history of ancient and recent polyploidy. Previous studies of allotetraploid common carp and goldfish (cyprinids)...

    Min-Rui-Xuan Xu, Zhen-Yang Liao, Jordan R. Brock, Kang Du in Nature Communications (2023)

  4. Article

    Open Access

    The effect of cuproptosis-relevant genes on the immune infiltration and metabolism of gynecological oncology by multiply analysis and experiments validation

    Gynecological cancers are a leading cause of mortality for women, including ovarian cancer (OC), cervical squamous cell carcinoma (CESC), and uterine corpus endometrial carcinoma (UCEC). Nevertheless, these gy...

    **ao-min Ran, Hui **ao, Yan-xiang Tang, **a **, **ng Tang in Scientific Reports (2023)

  5. Article

    Open Access

    Delta radiomics analysis for prediction of intermediary- and high-risk factors for patients with locally advanced cervical cancer receiving neoadjuvant therapy

    This study aimed to assess the feasibility of using magnetic resonance imaging (MRI)-based Delta radiomics characteristics extrapolated from the Ax LAVA + C series to identify intermediary- and high-risk facto...

    Rong-Rong Wu, Yi-Min Zhou, **ng-Yun **e, **-Yang Chen, Ke-Run Quan in Scientific Reports (2023)

  6. Article

    Open Access

    Effects of tumor-infiltrating lymphocytes on nonresponse rate of neoadjuvant chemotherapy in patients with invasive breast cancer

    High level of tumor-infiltrating lymphocytes (TILs) can predict the rate of total pathological complete remission (tpCR) of breast cancer patients who receive neoadjuvant chemotherapy (NACT). This study focuse...

    **ao-Long Qian, **ao-Qing **a, Ya-Qing Li, Yu-Mian Jia, Yuan-Yuan Sun in Scientific Reports (2023)

  7. Article

    Open Access

    Publisher Correction: Soil contamination in nearby natural areas mirrors that in urban greenspaces worldwide

    Yu-Rong Liu, Marcel G. A. van der Heijden, Judith Riedo in Nature Communications (2023)

  8. Article

    Open Access

    Soil contamination in nearby natural areas mirrors that in urban greenspaces worldwide

    Soil contamination is one of the main threats to ecosystem health and sustainability. Yet little is known about the extent to which soil contaminants differ between urban greenspaces and natural ecosystems. He...

    Yu-Rong Liu, Marcel G. A. van der Heijden, Judith Riedo in Nature Communications (2023)

  9. Article

    Open Access

    Serum/glucocorticoid-inducible kinase 1 deficiency induces NLRP3 inflammasome activation and autoinflammation of macrophages in a murine endolymphatic hydrops model

    Ménière’s disease, a multifactorial disorder of the inner ear, is characterized by severe vertigo episodes and hearing loss. Although the role of immune responses in Ménière’s disease has been proposed, the pr...

    Dao-Gong Zhang, Wen-Qian Yu, Jia-Hui Liu, Li-Gang Kong, Na Zhang in Nature Communications (2023)

  10. Article

    Open Access

    Tracking westerly wind directions over Europe since the middle Holocene

    The variability of the northern westerlies has been considered as one of the key elements for modern and past climate evolution. Their multiscale behavior and underlying control mechanisms, however, are incomp...

    Hsun-Ming Hu, Valerie Trouet, Christoph Spötl, Hsien-Chen Tsai in Nature Communications (2022)

  11. Article

    Open Access

    Reticulate evolution in the Pteris fauriei group (Pteridaceae)

    The Pteris fauriei group (Pteridaceae) has a wide distribution in Eastern Asia and includes 18 species with similar but varied morphology. We collected more than 300 specimens of the P. fauriei group and determin...

    Yi-Shan Chao, Atsushi Ebihara, Wen-Liang Chiou, Jer-Min Tsai in Scientific Reports (2022)

  12. Article

    Open Access

    Impact of different renal function equations on direct oral anticoagulant concentrations

    The purpose of this study is to investigate the correlation between glomerular filtration rate (GFR) estimated by different renal function equations and non-vitamin K antagonist oral anticoagulant concentratio...

    Shin-Yi Lin, Ching-Hua Kuo, Tao-Min Huang, Yu-Fong Peng in Scientific Reports (2021)

  13. Article

    Open Access

    Genomic signatures define three subtypes of EGFR-mutant stage II–III non-small-cell lung cancer with distinct adjuvant therapy outcomes

    The ADJUVANT study reported the comparative superiority of adjuvant gefitinib over chemotherapy in disease-free survival of resected EGFR-mutant stage II–IIIA non-small cell lung cancer (NSCLC). However, not all ...

    Si-Yang Liu, Hua Bao, Qun Wang, Wei-Min Mao, Yedan Chen in Nature Communications (2021)

  14. Article

    Open Access

    Soft, tough, and fast polyacrylate dielectric elastomer for non-magnetic motor

    Dielectric elastomer actuators (DEAs) with large electrically-actuated strain can build light-weight and flexible non-magnetic motors. However, dielectric elastomers commonly used in the field of soft actuatio...

    Li-Juan Yin, Yu Zhao, **g Zhu, Minhao Yang, Huichan Zhao in Nature Communications (2021)

  15. Article

    Open Access

    Dissecting spatial heterogeneity and the immune-evasion mechanism of CTCs by single-cell RNA-seq in hepatocellular carcinoma

    Little is known about the transcriptomic plasticity and adaptive mechanisms of circulating tumor cells (CTCs) during hematogeneous dissemination. Here we interrogate the transcriptome of 113 single CTCs from 4...

    Yun-Fan Sun, Liang Wu, Shi-** Liu, Miao-Miao Jiang, Bo Hu in Nature Communications (2021)

  16. Article

    Open Access

    Aging affects artemisinin synthesis in Artemisia annua

    Artemisinin (ART) is the most effective component in malaria treatment, however, the extremely low content restricts its clinical application. Therefore, it is urgent to increase the yield of ART. ART graduall...

    Jiao Li, **ao-Hui Chu, **ao-Yu Wang, Bao-Min Feng, Zong-**a Yu in Scientific Reports (2021)

  17. Article

    Open Access

    The Prostate Health Index aids multi-parametric MRI in diagnosing significant prostate cancer

    To evaluate the performance of the Prostate Health Index (PHI) in magnetic resonance imaging-transrectal ultrasound (MRI-TRUS) fusion prostate biopsy for the detection of clinically significant prostate cancer...

    Yu-Hua Fan, Po-Hsun Pan, Wei-Ming Cheng, Hsin-Kai Wang, Shu-Huei Shen in Scientific Reports (2021)

  18. Article

    Open Access

    Association between regional economic status and renal recovery of dialysis-requiring acute kidney injury among critically ill patients

    The association between regional economic status and the probability of renal recovery among patients with dialysis-requiring AKI (AKI-D) is unknown. The nationwide prospective multicenter study enrolled criti...

    Chih-Chung Shiao, Yu-Hsing Chang, Ya-Fei Yang, En-Tzu Lin in Scientific Reports (2020)

  19. Article

    Open Access

    Blocking C-Raf alleviated high-dose small-volume radiation-induced epithelial mesenchymal transition in mice lung

    The goal of this study was to develop a potential druggable target for lung injury after SABR through the small animal model. Utilising the model, a radiation dose of 70 Gy or 90 Gy was focally (small volume) ...

    Zhen-Yu Hong, Sanke Li, **aomei Liu, **ao-Min Leng, Zhanhui Miao in Scientific Reports (2020)

  20. Article

    Open Access

    Impact of cooking oil fume exposure and fume extractor use on lung cancer risk in non-smoking Han Chinese women

    Smoking tobacco is the major risk factor for develo** lung cancer. However, most Han Chinese women with lung cancer are nonsmokers. Chinese cooking methods usually generate various carcinogens in fumes that ...

    Tzu-Yu Chen, Yao-Hwei Fang, Hui-Ling Chen, Chin-Hao Chang, Hsin Huang in Scientific Reports (2020)

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