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Open AccessPolyurethane-based three-dimensional printing for biological mesh carriers
Repair and reconstruction of the myopectineal orifice area using meshes is the mainstay of surgical treatment of inguinal hernias. However, the limitations of existing meshes are becoming increasingly evident ...
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Article
Open AccessPrediction models combining zonulin, LPS, and LBP predict acute kidney injury and hepatorenal syndrome–acute kidney injury in cirrhotic patients
The development of acute kidney injury (AKI) and hepatorenal syndrome–acute kidney injury (HRS–AKI) in cirrhosis has been associated with intestinal barrier dysfunction and gut-kidney crosstalk. We use the rel...
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Open AccessHyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver
Hepatocellular carcinoma (HCC) is the most predominant primary malignancy in the liver. Genotoxic and genetic models have revealed that HCC cells are derived from hepatocytes, but where the critical region for...
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Open AccessAssessment of histologic prognostic factors of resectable rectal cancer: comparison of diagnostic performance using various apparent diffusion coefficient parameters
This study is to investigate optimum apparent diffusion coefficient (ADC) parameter for predicting lymphovascular invasion (LVI), lymph node metastasis (LNM) and histology type in resectable rectal cancer. 58 ...
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Open AccessGermline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk
In breast cancer, high levels of homeobox protein Hox-B13 (HOXB13) have been associated with disease progression of ER-positive breast cancer patients and resistance to tamoxifen treatment. Since HOXB13 p.G84E is...
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Open AccessCoA synthase regulates mitotic fidelity via CBP-mediated acetylation
The temporal activation of kinases and timely ubiquitin-mediated degradation is central to faithful mitosis. Here we present evidence that acetylation controlled by Coenzyme A synthase (COASY) and acetyltransf...
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Open AccessIntravoxel incoherent motion diffusion-weighted imaging for discriminating the pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer
To investigate the usefulness of intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) in discriminating the pathological complete response (pCR) to neoadjuvant chemoradiotherapy (nCRT) in locally...
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Open AccessHigh throughput cytotoxicity screening of anti-HER2 immunotoxins conjugated with antibody fragments from phage-displayed synthetic antibody libraries
Immunotoxins are an important class of antibody-based therapeutics. The potency of the immunotoxins depends on the antibody fragments as the guiding modules targeting designated molecules on cell surfaces. Pha...
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Open AccessCorrection: Corrigendum: Growth of semiconducting single-wall carbon nanotubes with a narrow band-gap distribution
Nature Communications 7: Article number: 11160 (2016); Published 30 March 2016; Updated 27 April 2016 This Article contains an error in Fig. 6. In Fig. 6a, the units on the y-axis should be ‘μA’ not ‘mA’.
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Open AccessGrowth of semiconducting single-wall carbon nanotubes with a narrow band-gap distribution
The growth of high-quality semiconducting single-wall carbon nanotubes with a narrow band-gap distribution is crucial for the fabrication of high-performance electronic devices. However, the single-wall carbon...
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Open AccessFunctioning free gracilis transfer to reconstruct elbow flexion and quality of life in global brachial plexus injured patients
In the study, the functional recovery and relative comprehensive quality of life of cases of global brachial plexus treated with free functioning muscle transfers were investigated. Patients who received funct...
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Open AccessPredominant structural configuration of natural antibody repertoires enables potent antibody responses against protein antigens
Humoral immunity against diverse pathogens is rapidly elicited from natural antibody repertoires of limited complexity. But the organizing principles underlying the antibody repertoires that facilitate this im...
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Open AccessEpigenetic memory gained by priming with osteogenic induction medium improves osteogenesis and other properties of mesenchymal stem cells
Mesenchymal stem cells (MSCs) are highly plastic cells that are able to transdifferentiate or dedifferentiate under appropriate conditions. In the present study, we reported here that after in vitro induction of ...
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Open AccessGenome of the Chinese tree shrew
Chinese tree shrews (Tupaia belangeri chinensis) possess many features valuable in animals used as experimental models in biomedical research. Currently, there are numerous attempts to employ tree shrews as model...