8 Result(s)

Article

Wild-type p53 upregulates an early onset breast cancer-associated gene GAS7 to suppress metastasis via GAS7–CYFIP1-mediated signaling pathway

The early onset breast cancer patients (age ≤ 40) often display higher incidence of axillary lymph node metastasis, and poorer five-year survival than the late-onset patients. To identify the genes and molecul...

Jer-Wei Chang, Wen-Hung Kuo, Chiao-Mei Lin, Wen-Ling Chen, Shih-Hsuan Chan… in Oncogene (2018)

Article

Validation of nomogram-revised risk index and comparison with other models for extranodal nasal-type NK/T-cell lymphoma in the modern chemotherapy era: indication for prognostication and clinical decision-making

Derived from our original nomogram study by using the risk variables from multivariable analyses in the derivation cohort of 1383 patients with extranodal NK/T-cell lymphoma, nasal-type (ENKTCL) who were mostl...

Si-Ye Chen, Yong Yang, Shu-Nan Qi, Ying Wang, Chen Hu, **a He, Li-Ling Zhang… in Leukemia (2021)

Article

Progression-free survival at 24 months and subsequent survival of patients with extranodal NK/T-cell lymphoma: a China Lymphoma Collaborative Group (CLCG) study

Limited evidence supports the use of early endpoints to evaluate the success of initial treatment of extranodal NK/T-cell lymphoma (ENKTCL) in the modern era. We aim to analyze progression-free survival at 24 ...

Yong Yang, Ying Wang, **n Liu, **a He, Li-Ling Zhang, Gang Wu, Bao-Lin Qu… in Leukemia (2021)

Article

Correction to: Progression-free survival at 24 months and subsequent survival of patients with extranodal NK/T-cell lymphoma: a China Lymphoma Collaborative Group (CLCG) study

Yong Yang, Ying Wang, **n Liu, **a He, Li-Ling Zhang, Gang Wu, Bao-Lin Qu… in Leukemia (2021)

Article

SARS-CoV-2 nucleocapsid protein triggers hyperinflammation via protein-protein interaction-mediated intracellular Cl⁻ accumulation in respiratory epithelium

SARS-CoV-2, the culprit pathogen of COVID-19, elicits prominent immune responses and cytokine storms. Intracellular Cl⁻ is a crucial regulator of host defense, whereas the role of Cl⁻ signaling pathway in modulat...

Lei Chen, Wei-Jie Guan, Zhuo-Er Qiu… in Signal Transduction and Targeted Therapy (2022)

Article

Mutational analysis of epidermolysis bullosa in Taiwan by whole-exome sequencing complemented by RNA sequencing: a series of 77 patients

Epidermolysis bullosa (EB) is a heterogeneous group of hereditary skin diseases characterized by skin fragility. Primary data on Taiwanese population remain scarce.

Wei-Ting Tu, **-Chen Hou, Peng-Chieh Chen… in Orphanet Journal of Rare Diseases (2022)

Article

SARS-CoV-2 envelope protein impairs airway epithelial barrier function and exacerbates airway inflammation via increased intracellular Cl⁻ concentration

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection disrupts the epithelial barrier and triggers airway inflammation. The envelope (E) protein, a core virulence structural component of coron...

Jian-Bang Xu, Wei-Jie Guan, Yi-Lin Zhang… in Signal Transduction and Targeted Therapy (2024)