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  1. Article

    Open Access

    Zuo ** Wan reverses P-gp-mediated drug-resistance by inhibiting activation of the PI3K/Akt/NF-κB pathway

    Zuo-**-Wan (ZJW), a traditional Chinese medicine formula, has been identified to be effective against drug resistance in cancer. In the present study, we investigated the effect of ZJW on acquired oxaliplatin...

    Hua Sui, Shu-Fang Pan, Yu Feng, Bao-Hui ** in BMC Complementary and Alternative Medicine (2014)

  2. Article

    Open Access

    Wild-type p53 upregulates an early onset breast cancer-associated gene GAS7 to suppress metastasis via GAS7–CYFIP1-mediated signaling pathway

    The early onset breast cancer patients (age ≤ 40) often display higher incidence of axillary lymph node metastasis, and poorer five-year survival than the late-onset patients. To identify the genes and molecul...

    Jer-Wei Chang, Wen-Hung Kuo, Chiao-Mei Lin, Wen-Ling Chen, Shih-Hsuan Chan in Oncogene (2018)

  3. Article

    Open Access

    Validation of nomogram-revised risk index and comparison with other models for extranodal nasal-type NK/T-cell lymphoma in the modern chemotherapy era: indication for prognostication and clinical decision-making

    Derived from our original nomogram study by using the risk variables from multivariable analyses in the derivation cohort of 1383 patients with extranodal NK/T-cell lymphoma, nasal-type (ENKTCL) who were mostl...

    Si-Ye Chen, Yong Yang, Shu-Nan Qi, Ying Wang, Chen Hu, **a He, Li-Ling Zhang in Leukemia (2021)

  4. Article

    Open Access

    Progression-free survival at 24 months and subsequent survival of patients with extranodal NK/T-cell lymphoma: a China Lymphoma Collaborative Group (CLCG) study

    Limited evidence supports the use of early endpoints to evaluate the success of initial treatment of extranodal NK/T-cell lymphoma (ENKTCL) in the modern era. We aim to analyze progression-free survival at 24 ...

    Yong Yang, Ying Wang, **n Liu, **a He, Li-Ling Zhang, Gang Wu, Bao-Lin Qu in Leukemia (2021)

  5. Article

    Correction to: Progression-free survival at 24 months and subsequent survival of patients with extranodal NK/T-cell lymphoma: a China Lymphoma Collaborative Group (CLCG) study

    Yong Yang, Ying Wang, **n Liu, **a He, Li-Ling Zhang, Gang Wu, Bao-Lin Qu in Leukemia (2021)

  6. Article

    Open Access

    Six-month follow-up of functional status in discharged patients with coronavirus disease 2019

    The long-term functional outcome of discharged patients with coronavirus disease 2019 (COVID-19) remains unresolved. We aimed to describe a 6-month follow-up of functional status of COVID-19 survivors.

    Hou-wei Du, Shuang-fang Fang, Sang-ru Wu, **ao-ling Chen in BMC Infectious Diseases (2021)

  7. Article

    Open Access

    Long-term outcomes of transanal endoscopic microsurgery for the treatment of rectal neuroendocrine tumors

    Transanal endoscopic microsurgery (TEM) has been accepted worldwide for the treatment of local rectal lesions. We aimed to assess the efficacy and safety of TEM in the treatment of rectal neuroendocrine tumors...

    Wei-Kun Shi, Rui Hou, Yun-Hao Li, **ao-Yuan Qiu, Yu-**n Liu, Bin Wu, Yi **ao in BMC Surgery (2022)

  8. Article

    Open Access

    SARS-CoV-2 nucleocapsid protein triggers hyperinflammation via protein-protein interaction-mediated intracellular Cl accumulation in respiratory epithelium

    SARS-CoV-2, the culprit pathogen of COVID-19, elicits prominent immune responses and cytokine storms. Intracellular Cl is a crucial regulator of host defense, whereas the role of Cl signaling pathway in modulat...

    Lei Chen, Wei-Jie Guan, Zhuo-Er Qiu in Signal Transduction and Targeted Therapy (2022)

  9. Article

    Open Access

    Efficacy of Multifocal Soft Contact Lenses in Reducing Myopia Progression Among Taiwanese Schoolchildren: A Randomized Paired-Eye Clinical Trial

    To evaluate the efficacy and safety of myopia control using a multifocal soft contact lens designed with high peripheral add power in schoolchildren.

    Yao-Lin Liu, Ken-Kuo Lin, Li-Sheng Cheng, Chao-Wen Lin in Ophthalmology and Therapy (2024)

  10. Article

    Open Access

    SARS-CoV-2 envelope protein impairs airway epithelial barrier function and exacerbates airway inflammation via increased intracellular Cl concentration

    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection disrupts the epithelial barrier and triggers airway inflammation. The envelope (E) protein, a core virulence structural component of coron...

    Jian-Bang Xu, Wei-Jie Guan, Yi-Lin Zhang in Signal Transduction and Targeted Therapy (2024)