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  1. Article

    Open Access

    MiR-30c-1-3p targets matrix metalloproteinase 9 involved in the rupture of abdominal aortic aneurysms

    Abdominal aortic aneurysm (AAA) can be fatal if ruptured, but there is no predictive biomarker. Our aim was to evaluate the prognostic potential of microRNAs (miRNAs/miRs) in an AAA mouse model and patients wi...

    Lin Yang, Hong-Gang Sui, Meng-Meng Wang, Jia-Yin Li in Journal of Molecular Medicine (2022)

  2. No Access

    Article

    VHL-HIF-2α axis-induced SMYD3 upregulation drives renal cell carcinoma progression via direct trans-activation of EGFR

    It has been well established that the von Hippel-Lindau/hypoxia-inducible factor α (VHL-HIFα) axis and epidermal growth factor receptor (EGFR) signaling pathway play a critical role in the pathogenesis and pro...

    Cheng Liu, Li Liu, Kun Wang, **ao-Feng Li, Li-Yuan Ge, Run-Zhuo Ma, Yi-Dong Fan in Oncogene (2020)

  3. No Access

    Article

    BMP10 suppresses hepatocellular carcinoma progression via PTPRS–STAT3 axis

    Bone morphogenetic protein 10 (BMP10), one member of the BMP family, is involved in various development events. Dysregulation of BMP10 has been observed in several diseases, including hypertensive cardiac hype...

    Yan-Mei Yuan, Ning Ma, Er-Bin Zhang, Tian-Wei Chen, Hao Jiang, Fen-Fen Yin in Oncogene (2019)

  4. No Access

    Article

    IL-17A promotes ventricular remodeling after myocardial infarction

    Inflammatory responses play an important role in the pathogenesis of adverse ventricular remodeling after myocardial infarction (MI). We previously demonstrated that interleukin (IL)-17A plays a pathogenic rol...

    Su-Feng Zhou, **g Yuan, Meng-Yang Liao, Ni **a in Journal of Molecular Medicine (2014)