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  1. Article

    Open Access

    C-reactive protein is a predictor for lower-extremity deep venous thrombosis in patients with primary intracerebral hemorrhage

    Our study aimed to determine whether there exists an association between low-grade systemic inflammation, as measured by serum C-reactive protein (CRP), and the risk of lower-extremity deep venous thrombosis (...

    Gang Wang, Bao-Fang Wu, Wen-Jun Zhao, Wei-Peng Hu in European Journal of Medical Research (2024)

  2. No Access

    Article

    Immunometabolism: a new dimension in immunotherapy resistance

    Immune checkpoint inhibitors (ICIs) have demonstrated unparalleled clinical responses and revolutionized the paradigm of tumor treatment, while substantial patients remain unresponsive or develop resistance to...

    Chaoyue **ao, Wei **ong, Yiting Xu, Ji’an Zou, Yue Zeng, Junqi Liu in Frontiers of Medicine (2023)

  3. No Access

    Article

    Treatment of Irritable Bowel Syndrome by Chinese Medicine: A Review

    Irritable bowel syndrome (IBS) is a common refractory disease. Chinese medicine (CM) has remarkable efficacy and advantages on the treatment of IBS. This review summarized the articles focusing on the treatmen...

    Guan-ru Chen, **ao-fang **e, Cheng Peng in Chinese Journal of Integrative Medicine (2023)

  4. No Access

    Article

    Ginsenoside Rg1 Reduces Cardiotoxicity While Increases Cardiotonic Effect of Aconitine in vitro

    To explore the synergic mechanism of ginsenoside Rg1 (Rg1) and aconitine (AC) by acting on normal neonatal rat cardiomyocytes (NRCMs) and pentobarbital sodium (PS)-induced damaged NRCMs.

    **n Xu, **ao-fang **e, Yan-hong Dong in Chinese Journal of Integrative Medicine (2022)

  5. No Access

    Article

    Kang-Ai Injection Inhibits Gastric Cancer Cells Proliferation through IL-6/STAT3 Pathway

    To explore the mechanisms underlying the proliferative inhibition of Chinese herbal medicine Kang-Ai injection (KAI) in gastric cancer cells.

    Chun-lei Zheng, Ke-zuo Hou, An-qi Wang in Chinese Journal of Integrative Medicine (2022)

  6. Article

    Open Access

    New-onset COVID-19–related diabetes: an early indicator of multi-organ injury and mortally of SARS-CoV-2 infection

    The pandemic of 2019 coronavirus (SARS-CoV-2) disease (COVID-19) has imposed a severe public health burden worldwide. Most patients with COVID-19 were mild. Severe patients progressed rapidly to critical condi...

    **-Kui Yang, Miao-Miao Zhao, Jian-Min **, Shi Liu, Peng Bai, Wei He in Current Medicine (2022)

  7. Article

    Open Access

    CREBBP/EP300 mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-associated macrophage polarization via FBXW7-NOTCH-CCL2/CSF1 axis

    Epigenetic alterations play an important role in tumor progression of diffuse large B-cell lymphoma (DLBCL). However, the biological relevance of epigenetic gene mutations on tumor microenvironment remains to ...

    Yao-Hui Huang, Kun Cai, Peng-Peng Xu, Li Wang in Signal Transduction and Targeted Therapy (2021)

  8. Article

    Open Access

    COVID-19 patients managed in psychiatric inpatient settings due to first-episode mental disorders in Wuhan, China: clinical characteristics, treatments, outcomes, and our experiences

    Data are scarce regarding the comorbid mental disorders and their management among COVID-19 patients. This study described the clinical characteristics and management of COVID-19 patients treated in psychiatri...

    Qin **e, Fang Fan, Xue-Peng Fan, **ao-Jiang Wang in Translational Psychiatry (2020)

  9. Article

    Exploring an Integrative Therapy for Treating COVID-19: A Randomized Controlled Trial

    To develop a new Chinese medicine (CM)-based drug and to evaluate its safety and effect for suppressing acute respiratory distress syndrome (ARDS) in COVID-19 patients.

    Jia-bo Wang, Zhong-xia Wang, **g **g in Chinese Journal of Integrative Medicine (2020)

  10. Article

    Open Access

    REX1 promotes EMT-induced cell metastasis by activating the JAK2/STAT3-signaling pathway by targeting SOCS1 in cervical cancer

    ZFP42 zinc finger protein (REX1), a pluripotency marker in mouse pluripotent stem cells, has been identified as a tumor suppressor in several human cancers. However, the function of REX1 in cervical cancer rem...

    Yu-Ting Zeng, **ao-Fang Liu, Wen-Ting Yang, Peng-Sheng Zheng in Oncogene (2019)

  11. No Access

    Article

    Predicting response to porcine antilymphocyte globulin plus cyclosporine A in children with acquired severe aplastic anemia

    In severe aplastic anemia (SAA), predictive markers of response to immunosuppressive therapy (IST) of porcine antilymphocyte globulin (pALG) have not been well defined. We investigated whether clinical and lab...

    Li-Peng Liu, **ao-Juan Chen, Wen-Yu Yang, Mei-Hui Yi, Kang Zhou in Pediatric Research (2019)

  12. No Access

    Article

    Diagnosis and treatment of cholangiocarcinoma: A consensus from surgical specialists of China

    Jian-qiang Cai, Shou-wang Cai, Wen-ming Cong in Journal of Huazhong University of Science … (2014)

  13. No Access

    Article

    In Vitro invasive pattern of hepatocellular carcinoma cell line HCCLM9 based on three-dimensional cell culture and quantum dots molecular imaging

    This study aimed to establish a new in vitro three-dimensional (3D) cell culture and use quantum dots (QDs) molecular imaging to examine the invasive behaviors of hepatocellular carcinoma (HCC) cells. Each well o...

    Min Fang 方 敏, Chun-wei Peng 彭春伟 in Journal of Huazhong University of Science … (2013)