5 Result(s)
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Article
**ao Hui Liew
English
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Article
Open AccessCellular Traction Force Holds the Potential as a Drug Testing Readout for In Vitro Cancer Metastasis
Metastasis is responsible for 90% of cancer-related deaths worldwide. However, the potential inhibitory effects of metastasis by various anticancer drugs have been left largely unexplored. Existing preclinical...
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Article
Open AccessEndothelial glycocalyx damage in kidney disease correlates with uraemic toxins and endothelial dysfunction
Damage to the endothelial glycocalyx is an early indicator of vascular damage and a potential marker of endothelial dysfunction. This study aimed to assess the relationship between markers of glycocalyx damage...
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Article
Diclofenac sex-divergent drug-drug interaction with Sunitinib: pharmacokinetics and tissue distribution in male and female mice
Coadministration of diclofenac and sunitinib, tyrosine kinase inhibitor, led to sex-divergent pharmacokinetic drug-drug interaction outcomes. Male and female mice were administered 60 mg/kg PO sunitinib alone ...
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Article
Sunitinib-paracetamol sex-divergent pharmacokinetics and tissue distribution drug-drug interaction in mice
The sex-divergent pharmacokinetics and interaction of tyrosine kinase inhibitor sunitinib with paracetamol was evaluated in male and female mice. Mice (control groups) were administered 60 mg/kg PO sunitinib a...
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Article
Sustainability assessment for biodiesel production via fuzzy optimisation during research and development (R&D) stage
Biodiesel is regarded as an important renewable fuel for meeting the global future energy demand and resolving the environmental problems (e.g. global warming). Despite its known advantages, it is still very c...
