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  1. Article

    Open Access

    Integrin αVβ3 antagonist-c(RGDyk) peptide attenuates the progression of ossification of the posterior longitudinal ligament by inhibiting osteogenesis and angiogenesis

    Ossification of the posterior longitudinal ligament (OPLL), an emerging heterotopic ossification disease, causes spinal cord compression, resulting in motor and sensory dysfunction. The etiology of OPLL remain...

    **angwu Geng, Yifan Tang, Changjiang Gu, Junkai Zeng, Yin Zhao… in Molecular Medicine (2024)

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  2. Article

    Open Access

    Exosomal miR-140-5p inhibits osteogenesis by targeting IGF1R and regulating the mTOR pathway in ossification of the posterior longitudinal ligament

    Ossification of the posterior longitudinal ligament (OPLL) is a disabling disease whose pathogenesis is still unclear, and there are no effective cures or prevention methods. Exosomal miRNA plays an important ...

    Yifan Tang, Yanqing Sun, Junkai Zeng, Bo Yuan, Yin Zhao… in Journal of Nanobiotechnology (2022)

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