111 Result(s)

Article

Targeting pro-inflammatory T cells as a novel therapeutic approach to potentially resolve atherosclerosis in humans

Atherosclerosis (AS), a leading cause of cardio-cerebrovascular disease worldwide, is driven by the accumulation of lipid contents and chronic inflammation. Traditional strategies primarily focus on lipid redu...

Lin Fan, Junwei Liu, Wei Hu, Zexin Chen, Jie Lan, Tongtong Zhang… in Cell Research (2024)

Article

Dynamic changes in RNA m⁶A and 5 hmC influence gene expression programs during macrophage differentiation and polarisation

RNA modifications are essential for the establishment of cellular identity. Although increasing evidence indicates that RNA modifications regulate the innate immune response, their role in monocyte-to-macropha...

Natalia Pinello, Renhua Song, Quintin Lee… in Cellular and Molecular Life Sciences (2024)

Article

Author Correction: Amyloid modifier SERF1a interacts with polyQ-expanded huntingtin-exon 1 via helical interactions and exacerbates polyQ-induced toxicity

Tien-Ying Tsai, Chun-Yu Chen, Tien-Wei Lin, Tien-Chang Lin… in Communications Biology (2024)

Article

The rise of baobab trees in Madagascar

The baobab trees (genus Adansonia) have attracted tremendous attention because of their striking shape and distinctive relationships with fauna¹. These spectacular trees have also influenced human culture, inspir...

Jun-Nan Wan, Sheng-Wei Wang, Andrew R. Leitch, Ilia J. Leitch, Jian-Bo Jian… in Nature (2024)

Article

Residential mobility and liver cancer risk: findings from a prospective cohort study in Chinese women

Residential mobility is believed to influence the occurrence and development of cancer; however, the results are inconclusive. Furthermore, limited studies have been conducted on Asian populations. This study ...

Jia-Yi Tuo, Qiu-Ming Shen, Zhuo-Ying Li, **g-Yu Tan, Jie Fang… in BMC Public Health (2024)

Article

Mini-dose methotrexate combined with methylprednisolone for the initial treatment of acute GVHD: a multicentre, randomized trial

There is an urgent unmet need for effective initial treatment for acute graft-versus-host disease (aGVHD) adding to the standard first-line therapy with corticosteroids after allogeneic haematopoietic stem cel...

Yu Wang, Qi-Fa Liu, De-Pei Wu, Zheng-Li Xu, Ting-Ting Han, Yu-Qian Sun… in BMC Medicine (2024)

Article

Diet and lifestyle behaviours simultaneously act on frailty: it is time to move the threshold of frailty prevention and control forward

To analyse the association among the simultaneous effects of dietary intake, daily life behavioural factors, and frailty outcomes in older Chinese women, we predicted the probability of maintaining physical ro...

Shan-lan Yang, Lei Wu, He-lang Huang, Lang-lang Zhang, Yi-xin Chen… in BMC Public Health (2024)

Article

Intrinsic and extrinsic actions of human neural progenitors with SUFU inhibition promote tissue repair and functional recovery from severe spinal cord injury

Neural progenitor cells (NPCs) derived from human pluripotent stem cells(hPSCs) provide major cell sources for repairing damaged neural circuitry and enabling axonal regeneration after spinal cord injury (SCI)...

Yong-Long Chen, **ang-Lan Feng, Kin-Wai Tam, Chao-Yang Fan… in npj Regenerative Medicine (2024)

Article

Reductive soil disinfestation by mixing carbon nanotubes and mushroom residues to mitigate the continuous crop** obstacles for Lilium Brownii

Reductive soil disinfestation can effectively alleviate continuous crop** obstacles. The effects of mixing mushroom residues and carbon nanotubes on the structure and function of soil microbial communities a...

Ding‑Di Tu, Rong Song, Bei Yan, **-Feng Dai, Hua Fang, Qian-Qi Zheng, Yi Gu… in Crop Health (2024)

Article

50 Years of quantum chromodynamics

Quantum Chromodynamics, the theory of quarks and gluons, whose interactions can be described by a local SU(3) gauge symmetry with charges called “color quantum numbers”, is reviewed; the goal of this review is...

Franz Gross, Eberhard Klempt, Stanley J. Brodsky… in The European Physical Journal C (2023)

Article

Author Correction: Amyloid modifier SERF1a interacts with polyQ-expanded huntingtin-exon 1 via helical interactions and exacerbates polyQ-induced toxicity

Tien-Ying Tsai, Chun-Yu Chen, Tien-Wei Lin, Tien-Chang Lin… in Communications Biology (2023)

Article

Research on the development methodology for clinical practice guidelines for organic integration of traditional Chinese and Western medicine

Integrated traditional Chinese medicine (TCM) and Western medicine (WM) is a new medical science grounded in the knowledge bases of both TCM and WM, which then forms a unique modern medical system in China. In...

Ying-Hui **, Yan-** Wang, Ying-Lan **e, Gui-Hua Tian… in Military Medical Research (2023)

Article

Efficacy of high-fidelity simulation in advanced life support training: a systematic review and meta-analysis of randomized controlled trials

Simulation is an increasingly used novel method for the education of medical professionals. This study aimed to systematically review the efficacy of high-fidelity (HF) simulation compared with low-fidelity (L...

Qin Zeng, Kai Wang, Wei-xin Liu, Jiu-zhi Zeng, **ng-lan Li… in BMC Medical Education (2023)

Article

Amyloid modifier SERF1a interacts with polyQ-expanded huntingtin-exon 1 via helical interactions and exacerbates polyQ-induced toxicity

Abnormal polyglutamine (polyQ) expansion and fibrillization occur in Huntington’s disease (HD). Amyloid modifier SERF enhances amyloid formation, but the underlying mechanism is not revealed. Here, the fibrill...

Tien-Ying Tsai, Chun-Yu Chen, Tien-Wei Lin, Tien-Chang Lin… in Communications Biology (2023)

Article

Intradermally delivered mRNA-encapsulating extracellular vesicles for collagen-replacement therapy

The success of messenger RNA therapeutics largely depends on the availability of delivery systems that enable the safe, effective and stable translation of genetic material into functional proteins. Here we sh...

Yi You, Yu Tian, Zhaogang Yang, Junfeng Shi… in Nature Biomedical Engineering (2023)

Article

Deep learning and ultrasound feature fusion model predicts the malignancy of complex cystic and solid breast nodules with color Doppler images

This study aimed to evaluate the performance of traditional-deep learning combination model based on Doppler ultrasound for diagnosing malignant complex cystic and solid breast nodules. A conventional statisti...

Han Liu, Chun-Jie Hou, **g-Lan Tang, Li-Tao Sun, Ke-Feng Lu… in Scientific Reports (2023)

Article

Atomic-scale manipulation of single-polaron in a two-dimensional semiconductor

Polaron is a composite quasiparticle derived from an excess carrier trapped by local lattice distortion, and it has been studied extensively for decades both theoretically and experimentally. However, atomic-s...

Huiru Liu, Aolei Wang, ** Zhang, Chen Ma, Caiyun Chen, Zijia Liu… in Nature Communications (2023)

Article

Iva xanthiifolia leaf extract reduced the diversity of indigenous plant rhizosphere bacteria

Iva xanthiifolia, native to North America, is now widely distributed in northeastern China and has become a vicious invasive plant. This article aims to probe the role of leaf extract in the invasion of I. xanthi...

Jia-wen Wu, Feng-lan Li, Shu-kuan Yao, Zi-yi Zhao, Xu Feng… in BMC Plant Biology (2023)

Article

Bound excitons and bandgap engineering in violet phosphorus

Violet phosphorus (VP), the most stable phosphorus allotrope, is a van der Waals semiconductor that can be used to construct p-type nanodevices. Recently, high-quality VP crystals have been synthesized while a de...

Zhenyu Sun, Zhihao Cai, Peng Cheng, Lan Chen… in npj 2D Materials and Applications (2023)

Article

PcTrim prevents early infection with white spot syndrome virus by inhibiting AP1-induced endocytosis

Viruses have evolved various strategies to achieve early infection by initiating transcription of their own early genes via host transcription factors, such as NF-κb, STAT, and AP1. How the host copes with thi...

**ao-Tong Cao, Lian-Jie Wu, Feng-Lin Xu, **n-Cang Li… in Cell Communication and Signaling (2023)