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  1. No Access

    Article

    Transplant of fecal microbiota from healthy young mice relieves cognitive defects in late-stage diabetic mice by reducing metabolic disorders and neuroinflammation

    Fecal microbiota transplant (FMT) is becoming as a promising area of interest for treating refractory diseases. In this study, we investigated the effects of FMT on diabetes-associated cognitive defects in mic...

    **an-xi Ye, Qiao-ying Jiang, Meng-jun Wu, Qing-huai Ye in Acta Pharmacologica Sinica (2024)

  2. No Access

    Article

    ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer’s disease mouse model

    Olfactory dysfunction is increasingly recognized as an early indicator of Alzheimer’s disease (AD). Aberrations in GABAergic function and the excitatory/inhibitory (E/I) balance within the olfactory bulb (OB) ...

    **an-hua Deng, **ng-yang Liu, Yi-hua Wei, Ke Wang in Acta Pharmacologica Sinica (2024)

  3. Article

    Open Access

    Signal enhancement ratio of multi-phase contrast-enhanced MRI: an imaging biomarker for survival in pancreatic adenocarcinoma

    To evaluate signal enhancement ratio (SER) for tissue characterization and prognosis stratification in pancreatic adenocarcinoma (PDAC), with quantitative histopathological analysis (QHA) as the reference stan...

    Cong **a, **-rong Qu, Yi-** Jiao, Chun-qiang Lu, Ben Zhao in European Radiology (2024)

  4. Article

    Open Access

    Age-related secretion of grancalcin by macrophages induces skeletal stem/progenitor cell senescence during fracture healing

    Skeletal stem/progenitor cell (SSPC) senescence is a major cause of decreased bone regenerative potential with aging, but the causes of SSPC senescence remain unclear. In this study, we revealed that macrophag...

    Nan-Yu Zou, Ran Liu, Mei Huang, Yu-Rui Jiao, Jie Wei, Yangzi Jiang in Bone Research (2024)

  5. No Access

    Article

    Quantification of ectopic fat storage in the liver and pancreas using six-point Dixon MRI and its association with insulin sensitivity and β-cell function in patients with central obesity

    To assess the association of ectopic fat deposition in the liver and pancreas quantified by Dixon magnetic resonance imaging (MRI) with insulin sensitivity and β-cell function in patients with central obesity.

    Meng-Jiao Cao, Wen-Jun Wu, **g-Wen Chen, **ang-Ming Fang, Ye Ren in European Radiology (2023)

  6. Article

    Open Access

    Measurement of anatomical parameters of anterior transpedicular root screw intervertebral fusion system of cervical spine

    This study aims to investigate the feasibility of the anterior transpedicular root screw (ATPRS) intervertebral fusion system for the cervical spine and provide a basis for the design of the ATPRS intervertebr...

    Sen-qi Ye, Liu-jun Zhao, Zhi-peng Hou, Ji-hui Zhang in BMC Musculoskeletal Disorders (2023)

  7. Article

    Open Access

    Prevalence and risk factors of tuberculosis among people living with HIV/AIDS in China: a systematic review and meta-analysis

    To estimate the prevalence and risk factors associated with tuberculosis (TB) among people living with human immunodeficiency virus (HIV) infection/acquired immunodeficiency syndrome (AIDS) in China.

    Cong-Cong Qi, Li-Ran Xu, Chang-Jia Zhao, Hai-Yan Zhang in BMC Infectious Diseases (2023)

  8. No Access

    Article

    Association Between Migraine and Ischemic Cardio-Cerebrovascular Disease (CCVD) and Effects of Triptans and Ergotamine on the Risk of Ischemic CCVD in Patients with Migraine in the Korean NHIS-HEALS Cohort

    Triptans and ergotamine are commonly used to treat migraine, a risk factor for ischemic stroke. This study aimed to investigate the association between migraine and ischemic cardio-cerebrovascular disease (CCV...

    Yonghwan Kim, Sang-Jun Shin, Jae-woo Lee, Ye-Seul Kim in Clinical Drug Investigation (2023)

  9. Article

    Open Access

    Modified Technique for Small-Incision Lenticule Extraction: Ye’s Swing Technique

    This study aimed to evaluate the lenticule integrity and refractive outcomes of a new technique, Ye’s swing technique, during small-incision lenticule extraction (SMILE).

    Jun Zhu, Fen-Fen Li, Qi Dai, Dan Cheng, Fang-Jun Bao in Ophthalmology and Therapy (2023)

  10. No Access

    Article

    Treatment outcome and efficacy of therapeutic plasma exchange for transplant-associated thrombotic microangiopathy in a large real-world cohort study

    The efficacy and outcome of therapeutic plasma exchange (TPE) for transplant-associated thrombotic microangiopathy (TA-TMA) remain controversial. We therefore sought to evaluate the outcome and efficacy of TPE...

    Li-** Yang, Peng Zhao, Ye-Jun Wu, Hai-**a Fu, Yun He in Bone Marrow Transplantation (2022)

  11. Article

    Exploring the impact of the COVID-19 epidemic on the medical emergency calls and calls for cardiovascular diseases in Hangzhou, China

    We aimed to evaluate the impact of the COVID-19 epidemic on emergency and cardiovascular disease–related calls in Hangzhou, China.

    Juan Chen, Yong-ran Cheng, **n-yan Fu in Irish Journal of Medical Science (1971 -) (2022)

  12. Article

    Open Access

    Antibiotics prescription for targeted therapy of pediatric invasive pneumococcal diseases in China: a multicenter retrospective study

    Streptococcus pneumoniae (S. pneumoniae) is a major cause of bacterial meningitis, septicemia and pneumonia in children. Inappropriate choice of antibiotic can have important adverse consequences for both the ind...

    Tian-ming Chen, Wen-hui Li, Fang Wang, Kun Tan, Qing-xiong Zhu in BMC Infectious Diseases (2021)

  13. Article

    Open Access

    Giant cell tumors of the mobile spine with invasion of adjacent vertebrae: an unusual imaging finding

    Giant cell tumors of the mobile spine invasion of the adjacent vertebrae are an ignored imaging finding.

    Gang Jiang, Ling-Ling Sun, Yong-Jun Ye, Zhi-Tao Yang in BMC Musculoskeletal Disorders (2021)

  14. Article

    Open Access

    Prognostic value of the NLR combined with CIP2A in the serum of patients with colorectal cancer

    This study aimed to investigate the prognostic value of CIP2A (cancerous inhibitor of protein phosphatase 2A) and the NLR (neutrophil–lymphocyte ratio) in the serum of patients with CRC (colorectal cancer) aft...

    Wei Chen, Hong-Jun Yi, **ao-Qiong Chen, Wan-Zhen **e, **ng-kui Tang in BMC Surgery (2021)

  15. No Access

    Article

    Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B

    Grincamycins (GCNs) are a class of angucycline glycosides isolated from actinomycete Streptomyces strains that have potent antitumor activities, but their antitumor mechanisms remain unknown. In this study, we tr...

    Zheng Wang, Zeng-xia Li, Wen-cao Zhao, Hong-bo Huang in Acta Pharmacologica Sinica (2021)

  16. No Access

    Article

    A gene-expression-based signature predicts survival in adults with T-cell lymphoblastic lymphoma: a multicenter study

    We aimed to establish a discriminative gene-expression-based classifier to predict survival outcomes of T-cell lymphoblastic lymphoma (T-LBL) patients. After exploring global gene-expression profiles of progre...

    **ao-Peng Tian, Dan **e, Wei-Juan Huang, Shu-Yun Ma, Liang Wang, Yan-Hui Liu in Leukemia (2020)

  17. No Access

    Article

    Association of continuous positive airway pressure with F2-isoprostanes in adults with obstructive sleep apnea: a meta-analysis

    Obstructive sleep apnea (OSA) is associated with increased F2-isoprostanes, a reliable standard biomarker of oxidative stress. Treatment with continuous positive airway pressure (CPAP) is effective for all deg...

    Zhi-Wei Huang, Wu Ouyang, Liang-Ji Zhang, Hao Li, Yu-Ming Ye in Sleep and Breathing (2019)

  18. No Access

    Article

    Prognostic and predictive value of a microRNA signature in adults with T-cell lymphoblastic lymphoma

    New prognostic factors are needed to establish indications for haematopoietic stem cell transplantation (HSCT) in first complete remission (CR1) for T-cell lymphoblastic lymphoma (T-LBL) patients. We used micr...

    **ao-Peng Tian, Wei-Juan Huang, Hui-Qiang Huang, Yan-Hui Liu, Liang Wang in Leukemia (2019)

  19. Article

    Open Access

    The effect of quality of segmental bowel preparation on adenoma detection rate

    The effectiveness in surveillance colonoscopy largely depends on the quality of bowel preparation. We aimed to investigate the quality of bowel preparation segmentally and its effect on Adenoma Detection Rate ...

    Rui Guo, Yong-Jun Wang, Mo Liu, Jun Ge, Ling-Ye Zhang, Ling Ma in BMC Gastroenterology (2019)

  20. Article

    Open Access

    Survey of integrative lumbar spinal stenosis treatment in Korean medicine doctors: preliminary data for clinical practice guidelines

    Considering that large variations exist amongst practitioners in lumbar disorder management and the significant costs that lumbar disorders incur, determining clinical practice patterns to provide preliminary ...

    Yoon Jae Lee, Joon-Shik Shin, **ho Lee in BMC Complementary and Alternative Medicine (2017)

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