117 Result(s)
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Open AccessIntracellular immunity to HIV-1: newly defined retroviral battles inside infected cells
Studies of the human immunodeficiency virus type 1 (HIV-1) continue to enrich eukaryotic biology and immunology. Recent advances have defined factors that function after viral entry and prevent the replication...
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Open AccessRetrospective study of adenovirus in autopsied pulmonary tissue of pediatric fatal pneumonia in South China
Adenovirus are the important pathogen of pediatric severe pneumonia. The aim of this study is to analyze the infection, subtype and distribution of adenovirus in autopsied pulmonary tissue of fatal pneumonia i...
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Open AccessA novel HIV-1 restriction factor that is biologically distinct from APOBEC3 cytidine deaminases in a human T cell line CEM.NKR
Isolation of novel retroviral restriction factors will open new avenues for anti-HIV/AIDS treatment. Although HIV-1 replication is restricted by APOBEC3G/APOBEC3F, TRIM5α, and CD317, none defend HIV-1 infectio...
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Open AccessRetrospective analysis of nosocomial infections in the intensive care unit of a tertiary hospital in China during 2003 and 2007
Nosocomial infections are a major threat to patients in the intensive care unit (ICU). Limited data exist on the epidemiology of ICU-acquired infections in China. This retrospective study was carried out to de...
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Open AccessLong persistence of EV71 specific nucleotides in respiratory and feces samples of the patients with Hand-Foot-Mouth Disease after recovery
EV71 is associated with the fatal cases of brain stem encephalitis during large HFMD outbreaks from 1998 to 2008. EV71 may continuously shed from upper respiratory tracts and feces of HFMD patients for relativ...
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Open AccessSeroprevalence of Toxoplasma gondii infection in dairy goats in Shaanxi Province, Northwestern China
Toxoplasma gondii is an important zoonotic pathogen causing significant human and animal health problems. Infection in dairy goats not only results in significant reproductive losses, but also represents an impor...
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Open AccessSeroprevalence of Toxoplasma gondii infection in pet dogs in Lanzhou, Northwest China
In recent years, surveys of Toxoplasma gondii infection in dogs have been reported worldwide, including China. However, little is known about the prevalence of T. gondii in pet dogs in Northwest China. In the pre...
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Open AccessPrevalence of Clonorchis sinensis infection in dogs and cats in subtropical southern China
Clonorchiasis, caused by Clonorchis sinensis, is one of the major parasitic zoonoses in China, particularly in China's southern Guangdong province where the prevalence of C. sinensis infection in humans is high. ...
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Open AccessSeroprevalence of Toxoplasma gondii infection in household and stray cats in Lanzhou, northwest China
Toxoplasma gondii is an important protozoan parasite infecting humans and almost all warm-blooded animals. As the only definitive host, cats play a crucial role in the transmission of T. gondii infection by shedd...
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Open AccessA Google Earth-based surveillance system for schistosomiasis japonica implemented in the lower reaches of the Yangtze River, China
Due to the success of the national schistosomiasis control programme in China, transmission has been sufficiently reduced in many areas to severely limit identification of areas at risk by conventional snail s...
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Open AccessTransmissibility and temporal changes of 2009 pH1N1 pandemic during summer and fall/winter waves
In order to compare the transmissibility of the 2009 pH1N1 pandemic during successive waves of infections in summer and fall/winter in the Northern Hemisphere, and to assess the temporal changes during the cou...
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Open AccessStray dogs as indicators of Toxoplasma gondii distributed in the environment: the first report across an urban-rural gradient in China
Toxoplasmosis is an important parasitic zoonosis caused by the protozoan Toxoplasma gondii that is distributed world-wide and infects a variety of hosts. However, the prevalence of T. gondii in the environment (s...
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Open AccessSeroprevalence of Toxoplasma gondii infection in dairy cattle in southern China
As an obligate intracellular parasite, Toxoplasma gondii can infect humans and almost all warm-blooded animals. The consumption of raw or undercooked beef and milk is considered a risk for T. gondii infection in ...
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Open AccessFirst report of Toxoplasma gondii infection in market-sold adult chickens, ducks and pigeons in northwest China
Toxoplasma gondii infection is a global concern, affecting a wide range of warm-blooded animals and humans worldwide, including poultry. Domestic and companion birds are considered to play an important role in th...
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Open AccessFunctional characterization of an arrestin gene on insecticide resistance of Culex pipiens pallens
Continuous and excessive application of insecticides has resulted in the rapid development of insecticide resistance in several mosquito species, including Culex pipiens pallens. Previous studies in our laborator...
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Open AccessCanine and feline parasitic zoonoses in China
Canine and feline parasitic zoonoses have not been given high priority in China, although the role of companion animals as reservoirs for zoonotic parasitic diseases has been recognized worldwide. With an incr...
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Open AccessEmergence of extensively drug-resistant Acinetobacter baumannii complex over 10 years: Nationwide data from the Taiwan Surveillance of Antimicrobial Resistance (TSAR) program
Acinetobacter baumannii complex (ABC) has emerged as an important pathogen causing a variety of infections. Longitudinal multicenter surveillance data on ABC from different sources in Taiwan have not been publis...
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Open AccessFirst report of Toxoplasma gondii seroprevalence in peafowls in Yunnan Province, Southwestern China
Toxoplasma gondii is an intracellular protozoan parasite infecting almost all warm-blooded animals, including birds, with a worldwide distribution. Surveys of T. gondii infection in wild birds have been reported ...
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Open AccessEvidence for Vpr-dependent HIV-1 Replication in Human CD4+CEM.NKR T-Cells
Vpr is exclusively expressed in primate lentiviruses and contributes to viral replication and disease progression in vivo. HIV-1 Vpr has two major activities in vitro: arrest of cell cycle in the G2 phase (G2 ...
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Open AccessGenetic diversity among Toxoplasma gondii strains from different hosts and geographical regions revealed by sequence analysis of GRA5 gene
Toxoplasma gondii is a highly prevalent protozoan parasite infecting a wide range of animals and humans. The epidemiological and biological diversity of T. gondii has resulted in a high genetic variation and unus...
