282 Result(s)
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**an-zhong Zhou
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Serum IgA as a Prognostic Beacon: Anticipating Systemic Therapy Efficacy in Metastatic Clear Cell Renal Cell Carcinoma
Immunotherapy-tyrosine kinase inhibitor (IO-TKI) therapy has revolutionized the treatment landscape for metastatic clear cell renal cell carcinoma (mccRCC); however, the absence of effective biomarkers poses a...
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Open AccessStudy of baryon number transport dynamics and strangeness conservation effects using \(\Omega\) -hadron correlations
In nuclear collisions at RHIC energies, an excess of \(\Omega\) Ω hyperons ...
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Open AccessTMC6 functions as a GPCR-like receptor to sense noxious heat via Gαq signaling
Thermosensation is vital for the survival, propagation, and adaption of all organisms, but its mechanism is not fully understood yet. Here, we find that TMC6, a membrane protein of unknown function, is highly ...
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Seasonal variation in urinary PAH metabolite levels and associations with neonatal birth outcomes
Previous studies have demonstrated that exposure to polycyclic aromatic hydrocarbons (PAHs) can affect maternal and infant health. However, the conclusions regarding the effects of seasonal PAH exposure on mat...
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Open AccessPD-1/CD80+ small extracellular vesicles from immunocytes induce cold tumours featured with enhanced adaptive immunosuppression
Only a minority of cancer patients benefit from immune checkpoint blockade therapy. Sophisticated cross-talk among different immune checkpoint pathways as well as interaction pattern of immune checkpoint molec...
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Isovector giant dipole resonance mode with an improved propagation approach in the framework of EQMD model
The Extended Quantum Molecular Dynamics (EQMD) model is one of the few QMD-like transport approaches that can describe the \(\alpha \) ...
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Research progress of permanent ferrite magnet materials
Permanent ferrite magnet materials are extensively employed due to their exceptional magnetic properties and cost-effectiveness. The fast development in electromobile and household appliance industries contrib...
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Author Correction: Ginsenoside Rg1 protects against ischemic/reperfusion-induced neuronal injury through miR-144/Nrf2/ARE pathway
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Open AccessEnhanced cellular therapy: revolutionizing adoptive cellular therapy
Enhanced cellular therapy has emerged as a novel concept following the basis of cellular therapy. This treatment modality applied drugs or biotechnology to directly enhance or genetically modify cells to enhan...
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Mammalian PIWI–piRNA–target complexes reveal features for broad and efficient target silencing
The PIWI-interacting RNA (piRNA) pathway is an adaptive defense system wherein piRNAs guide PIWI family Argonaute proteins to recognize and silence ever-evolving selfish genetic elements and ensure genome inte...
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Open AccessIncreasing the robustness of Escherichia coli for aromatic chemicals production through transcription factor engineering
Engineering microbial cell factories has been widely used to produce a variety of chemicals, including natural products, biofuels, and bulk chemicals. However, poor robustness limits microbial production on an...
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Effects of Prenatal Polycyclic Aromatic Hydrocarbon Exposure on Neonatal Outcomes—MLR and BKMR Models
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants that pose a potentially serious threat to maternal and infant health, yet there are few studies on low-dose maternal and infant h...
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Open AccessNanobiolubricant grinding: a comprehensive review
Minimum quantity lubrication (MQL), which considers the cost, sustainability, flexibility, and quality, has been actively explored by scholars. Nanoadditive phases have been widely investigated as atomizing me...
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Design and application of copper/lithium composite anodes for advanced lithium metal batteries
Lithium (Li) is a promising candidate for next-generation battery anode due to its high theoretical specific capacity and low reduction potential. However, safety issues derived from the uncontrolled growth of...
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Open AccessLow pressure reversibly driving colossal barocaloric effect in two-dimensional vdW alkylammonium halides
Plastic crystals as barocaloric materials exhibit the large entropy change rivalling freon, however, the limited pressure-sensitivity and large hysteresis of phase transition hinder the colossal barocaloric ef...
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Nondestructive technique for identifying nuclides using neutron resonance transmission analysis at CSNS Back-n
Nondestructive and noninvasive neutron assays are essential applications of neutron techniques. Neutron resonance transmission analysis (NRTA) is a powerful nondestructive method for investigating the elementa...
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Black holes as the source of dark energy: A stringent test with high-redshift JWST AGNs
Studies have proposed that there is evidence for cosmological coupling of black holes (BHs) with an index of k ≈ 3; hence, BHs serve as the astrophysical source of dark energy. However, the data sample is limited...
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Open AccessADP-dependent glucokinase controls metabolic fitness in prostate cancer progression
Cell metabolism plays a pivotal role in tumor progression, and targeting cancer metabolism might effectively kill cancer cells. We aimed to investigate the role of hexokinases in prostate cancer (PCa) and iden...
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Ethyl Lithospermate Reduces Lipopolysaccharide-Induced Inflammation through Inhibiting NF-κB and STAT3 Pathways in RAW 264.7 Cells and Zebrafish
To explore the anti-inflammatory effects of ethyl lithospermate in lipopolysaccharide (LPS)-stimulated RAW 264.7 murine-derived macrophages and zebrafish, and its underlying mechanisms.
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Effects of Compound Danshen Drip** Pills on Ventricular Remodeling and Cardiac Function after Acute Anterior Wall ST-Segment Elevation Myocardial Infarction (CODE-AAMI): Protocol for a Randomized Placebo-Controlled Trial
Ventricular remodeling after acute anterior wall ST-segment elevation myocardial infarction (AAMI) is an important factor in occurrence of heart failure which additionally results in poor prognosis. Therefore,...
