25 Result(s)
within
Medicine & Public Health
Internal Medicine
**an-Tong Chen
Article
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Article
JEM-1, a novel gene encoding a leucine-zipper nuclear factor upregulated during retinoid-induced maturation of NB4 promyelocytic leukaemia
Retinoid-induced proliferation causing hyperleukocytosis is a severe complication of retinoid therapy in t(15;17) acute promyelocytic leukaemia. The molecular basis of this phenomenon is unknown. It is possibl...
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40th EASD Annual Meeting of the European Association for the Study of Diabetes
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Angiogenesis and clinicopathologic characteristics in different hepatocellular carcinoma subtypes defined by EpCAM and α-fetoprotein expression status
Recently, two hepatic lineage markers epithelial cell adhesion molecule (EpCAM) and α-fetoprotein (AFP) were used to classify hepatocellular carcinoma (HCC) into four subtypes with prognostic implication. In t...
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Open AccessClinical significance of combined detection of human papilloma virus infection and human telomerase RNA component gene amplification in patients with squamous cell carcinoma of the esophagus in northern China
The aim of the study was to test for human papilloma virus (HPV) infection and human telomerase RNA component (hTERC) gene amplification in tissues derived from esophageal cancer, in esophagus displaying atypi...
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RETRACTED ARTICLE: Metabolic syndrome factors and risk of postoperative depression in high-grade glioma patients in a 1.5-year prospective study
To date, the relationship between metabolic syndrome factors and the risk of glioma-related depression is still unclear, and no study investigates this relationship. Our aim was to investigate the relationship...
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Upregulation of podocyte-secreted angiopoietin-like-4 in diabetic nephropathy
Podocyte injury plays a key role in the development of diabetic nephropathy (DN). Understanding the changes in podocyte structure and function in diabetes mellitus may lead to novel diagnostic tools and treatm...
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Open AccessWorld Congress Integrative Medicine & Health 2017: part two
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Open AccessWorld Congress Integrative Medicine & Health 2017: Part one
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Open AccessWorld Congress Integrative Medicine & Health 2017: part three
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Retraction Note to: Metabolic syndrome factors and risk of postoperative depression in high-grade glioma patients in a 1.5-year prospective study
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Open AccessDEAD-box helicase 27 promotes colorectal cancer growth and metastasis and predicts poor survival in CRC patients
Copy number alterations (CNAs) are crucial for colorectal cancer (CRC) development. In this study, DEAD box polypeptide 27 (DDX27) was identified to be highly amplified in both TCGA CRC (474/615) and primary C...
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Open AccessCD22 CAR T-cell therapy in refractory or relapsed B acute lymphoblastic leukemia
Despite worldwide promising clinical outcome of CD19 CAR-T therapy, relapse after this therapy is associated with poor prognosis and has become an urgent problem to be solved. We conducted a CD22 CAR T-cell th...
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Open AccessA novel CDK9 inhibitor increases the efficacy of venetoclax (ABT-199) in multiple models of hematologic malignancies
MCL-1 is one of the most frequently amplified genes in cancer, facilitating tumor initiation and maintenance and enabling resistance to anti-tumorigenic agents including the BCL-2 selective inhibitor venetocla...
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Open AccessAssociation between admission hypothermia and outcomes in very low birth weight infants in China: a multicentre prospective study
The objective of this prospective, multicentre, observational cohort study was to evaluate the association between admission hypothermia and neonatal outcomes in very low-birth weight (VLBW) infants in multipl...
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Open AccessMyricanol 5-fluorobenzyloxy ether regulation of survivin pathway inhibits human lung adenocarcinoma A549 cells growth in vitro
This study aimed to explore the growth inhibitory effect of myricanol 5-fluorobenzyloxy ether (5FEM) and its underlying mechanisms in human lung adenocarcinoma A549 cells in vitro.
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Harnessing chlorin e6 loaded by functionalized iron oxide nanoparticles linked with glucose for target photodynamic therapy and improving of the immunogenicity of lung cancer
Non-small-cell lung cancer (NSCLC) is the most common malignant lung tumor and is difficult to be eradicated due to its immunosuppressive microenvironment. Chlorin e6 (Ce6)-mediated photodynamic therapy (PDT) ...
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TMCO1 expression promotes cell proliferation and induces epithelial–mesenchymal transformation in human gliomas
Transmembrane and coiled-coil domains 1 (TMCO1) is a recently discovered transmembrane protein of endoplasmic reticulum (ER), which plays a critical role in maintaining calcium homeostasis. TMCO1 dysfunction h...
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Identification of a novel Calpain-2-SRC feed-back loop as necessity for β-Catenin accumulation and signaling activation in hepatocellular carcinoma
Rapid progression is the major cause of the poor prognosis of hepatocellular carcinoma (HCC); however, the underlying mechanism remained unclear. Here, we found Calpain-2 (CAPN2), a well-established protease t...
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Diet and gastric cancer risk: an umbrella review of systematic reviews and meta-analyses of prospective cohort studies
Several systematic reviews and meta-analyses evaluated the associations between dietary factors and the incidence of gastric cancer (GC).
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Open AccessImatinib blocks tyrosine phosphorylation of Smad4 and restores TGF-β growth-suppressive signaling in BCR-ABL1-positive leukemia
Loss of TGF-β-mediated growth suppression is a major contributor to the development of cancers, best exemplified by loss-of-function mutations in genes encoding components of the TGF-β signaling pathway in col...
