2,539 Result(s)

Article

Novel associations between MTDH gene polymorphisms and invasive ductal breast cancer: a case–control study

To reveal the contributing effects of MTDH gene SNPs in the risk of invasive ductal breast cancer (IDC).

Yan Huang, Dan Dai, Li Zhu, **anzhong Qi in Discover Oncology (2024)

Article

Correction: Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma

Fei **ong, Da Wang, Wei **ong, **n Wang… in Journal of Experimental & Clinical Cancer … (2024)

Article

Localized fine-tuning and clinical evaluation of deep-learning based auto-segmentation (DLAS) model for clinical target volume (CTV) and organs-at-risk (OAR) in rectal cancer radiotherapy

Various deep learning auto-segmentation (DLAS) models have been proposed, some of which have been commercialized. However, the issue of performance degradation is notable when pretrained models are deployed in...

Jianhao Geng, **n Sui, Rongxu Du, Jialin Feng, Ruoxi Wang… in Radiation Oncology (2024)

Article

Differences in the risk of immune-related pneumonitis between PD-1 and PD-L1 inhibitors: a meta-analysis according to the new mirror-principle and PRISMA guidelines

To compare the risk of immune-associated pneumonitis between PD-1 and PD-L1 inhibitors, the meta-analysis was designed.

Yuan Tian, Zongxiu Yin, Chi Zhang, Zhuoqi Li… in Cancer Immunology, Immunotherapy (2024)

Article

Neoadjuvant chemotherapy with or without camrelizumab in resectable esophageal squamous cell carcinoma: the randomized phase 3 ESCORT-NEO/NCCES01 trial

Recent single-arm studies involving neoadjuvant camrelizumab, a PD-1 inhibitor, plus chemotherapy for resectable locally advanced esophageal squamous cell carcinoma (LA-ESCC) have shown promising results. This...

Jianjun Qin, Liyan Xue, Anlin Hao, **aofeng Guo, Tao Jiang, Yunfeng Ni… in Nature Medicine (2024)

Article

YAP inhibition overcomes adaptive resistance in HER2-positive gastric cancer treated with trastuzumab via the AKT/mTOR and ERK/mTOR axis

Human epidermal growth factor receptor 2 (HER2)-positive gastric cancer (GC) is a heterogeneous GC subtype characterized by the overexpression of HER2. To date, few specific targeted therapies have demonstrate...

Jiao Qiao, Mei Feng, Wenyuan Zhou, Yuan Tan, Shuo Yang, Qi Liu… in Gastric Cancer (2024)

Article

MTF1 genetic variants are associated with lung cancer risk in the Chinese Han population

Metal-regulatory transcription factor 1 (MTF1), a conserved metal-binding transcription factor in eukaryotes, regulates the proliferation of cancer cells by activating downstream target genes and then particip...

Yu**g Cheng, Chan Zhang, Qi Li, **n Yang, Wanlu Chen, KunHua He… in BMC Cancer (2024)

Article

Shikonin blocks CAF-induced TNBC metastasis by suppressing mitochondrial biogenesis through GSK-3β/NEDD4-1 mediated phosphorylation-dependent degradation of PGC-1α

Triple-negative breast cancer (TNBC) is characterized by its high metastatic potential, which results in poor patient survival. Cancer-associated fibroblasts (CAFs) are crucial in facilitating TNBC metastasis ...

Shuangqin Fan, **aomin Yan, **aoxia Hu… in Journal of Experimental & Clinical Cancer … (2024)

Article

Liver cancer from the perspective of single-cell sequencing: a review combined with bibliometric analysis

Liver cancer (LC) is a prevalent malignancy and a leading cause of cancer-related mortality worldwide. Extensive research has been conducted to enhance patient outcomes and develop effective prevention strateg...

Yanwei Ji, Qi An, **nyu Wen, Zhou Xu… in Journal of Cancer Research and Clinical On… (2024)

Article

LINC00525 enhances ZNF460-regulated CD24 expression through the sponge miR-125a-5p to promote malignant progression of breast cancer

CD24 is a highly glycosylated glycosylphosphatidylinositol anchored membrane protein that plays an important role in tumor progression. The aim of this study was to investigate the effect of abnormal expressio...

Jun Wang, Ji Shi, Yuan **ang, Zhi-Wen Wang… in Journal of Cancer Research and Clinical On… (2024)

Article

Constructing a prognostic model for colon cancer: insights from immunity-related genes

Colon cancer (CC) is a malignancy associated with significant morbidity and mortality within the gastrointestinal tract. Recurrence and metastasis are the main factors affecting the prognosis of CC patients un...

Ansu Li, Qi Li, Chaoshan Wang, Xue Bao, Feng Sun, ** Qian, Wu Sun in BMC Cancer (2024)

Article

Apatinib combined with temozolomide in diffuse midline glioma: a novel and effective therapy

Diffuse midline glioma (DMG), H3 K27M-mutant is a type of diffuse high-grade glioma that occurs in the brain midline carrying an extremely poor prognosis under the best efforts of surgery, radiation, and other...

Yu-An Li, Chuan Zhao, **g-**g Ge, Cheng Li, Feng-Jun Xue, Shao-Pei Qi… in BMC Cancer (2024)

Article

CTR > 0.7 predicts the subgroup of lung adenocarcinomas ≤ 2 cm at risk of poor outcome treated by sublobar resection compared to lobar resection

A standard surgical procedure for patients with small early-stage lung adenocarcinomas remains unknown. Hence, we aim in this study to assess the clinical utility of the consolidation-to-tumor ratio (CTR) when...

Weiwei **g, Qi Li, Mengxi Liu, Yi Zhang, Sifan Chen, Ke Zhang, Dan Li… in Cancer Imaging (2024)

Article

CRISPR/Cas9-based genome-wide screening for metastasis ability identifies FCGR1A regulating the metastatic process of ovarian cancer by targeting LSP1

Metastasis is a main cause of death from ovarian cancer (OC). Identifying key markers involved in OC metastasis can aid in the effective detection of early postoperative metastasis. However, the role of FCGR1A...

Yingying Qi, Weiyan Zhu, Kexin Mo, Hui Jiang in Journal of Cancer Research and Clinical On… (2024)

Article

The role of minimal residual disease and serum free light chain ratio in the management of multiple myeloma

Multiple myeloma (MM) denotes a cancerous growth characterized by abnormal proliferation of plasma cells. Growing evidence suggests that the complexity in addressing MM lies in the presence of minimal residual...

Long-Ying Zhu, Qi-Lei Hu, Liang Zhang, Zuo-Jie Li in Discover Oncology (2024)

Article

Author Correction: RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis

Zhentao Yang, Yan Wang, Yingying Zhang, **adi He, Chuan-Qi Zhong… in Nature Cell Biology (2024)