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  1. Article

    Open Access

    Genetic deletion of Krüppel-like factor 11 aggravates traumatic brain injury

    The long-term functional recovery of traumatic brain injury (TBI) is hampered by pathological events, such as parenchymal neuroinflammation, neuronal death, and white matter injury. Krüppel-like transcription ...

    Chao Zhou, ** Sun, Milton H. Hamblin, Ke-Jie Yin in Journal of Neuroinflammation (2022)

  2. Article

    Open Access

    Non-coding RNAs in the regulation of blood–brain barrier functions in central nervous system disorders

    The blood–brain barrier (BBB) is an essential component of the neurovascular unit that controls the exchanges of various biological substances between the blood and the brain. BBB damage is a common feature of...

    ** Sun, Milton H. Hamblin, Ke-Jie Yin in Fluids and Barriers of the CNS (2022)

  3. Article

    Retraction Note: Chrysophanol suppresses growth and metastasis of T cell acute lymphoblastic leukemia via miR-9/PD-L1 axis

    This article has been retracted. Please see the Retraction Notice for more detail:https://doi.org/10.1007/s00210-020-02026-6.

    Junjie Yin, Qingsong Yin, Bo Liang in Naunyn-Schmiedeberg's Archives of Pharmaco… (2021)

  4. No Access

    Article

    RETRACTED ARTICLE: Chrysophanol suppresses growth and metastasis of T cell acute lymphoblastic leukemia via miR-9/PD-L1 axis

    T cell acute lymphoblastic leukemia (T-ALL) was a malignant lymphoma. Therefore, the development of novel therapeutic agents against T-ALL is imperative. Previous studies have s...

    Junjie Yin, Qingsong Yin, Bo Liang in Naunyn-Schmiedeberg's Archives of Pharmaco… (2020)

  5. No Access

    Article

    Altered Dynamic Functional Network Connectivity in Frontal Lobe Epilepsy

    Frontal lobe epilepsy has recently been associated with disrupted brain functional connectivity; variations among various resting-state networks (RSNs) across time remains largely unclear. This study applied d...

    Benjamin Klugah-Brown, Cheng Luo, Hui He, Sisi Jiang in Brain Topography (2019)

  6. No Access

    Article

    Genetic Deletion of Krüppel-Like Factor 11 Aggravates Ischemic Brain Injury

    Krüppel-like factors (KLFs) belong to the zinc finger family of transcription factors, and their function in the CNS is largely unexplored. KLF11 is a member of the KLF family, and we have previously demonstra...

    Xuelian Tang, Kai Liu, Milton H. Hamblin, Yun Xu, Ke-Jie Yin in Molecular Neurobiology (2018)

  7. Article

    Open Access

    Interaction of basolateral amygdala, ventral hippocampus and medial prefrontal cortex regulates the consolidation and extinction of social fear

    Following a social defeat, the balanced establishment and extinction of aversive information is a beneficial strategy for individual survival. Abnormal establishment or extinction is implicated in the developm...

    Chu-Chu Qi, Qing-Jun Wang, Xue-zhu Ma, Hai-Chao Chen in Behavioral and Brain Functions (2018)

  8. No Access

    Article

    Glucose enhances rotavirus enterotoxin-induced intestinal chloride secretion

    Rotavirus causes severe diarrhea in small children and is typically treated using glucose-containing oral rehydration solutions; however, glucose may have a detrimental impact on these patients, because it inc...

    Liangjie Yin, Rejeesh Menon, Reshu Gupta in Pflügers Archiv - European Journal of Phys… (2017)

  9. No Access

    Article

    Resting State fMRI Demonstrates a Disturbance of the Cerebello-Cortical Circuit in Essential Tremor

    Individuals with essential tremor (ET) have postural and active movement abnormalities. Disturbances in the cerebello-thalamo-cortical circuit may contribute to the several motor symptoms of ET. Resting state ...

    Wenjie Yin, Wei Lin, Wenbo Li, Shusen Qian, **n Mou in Brain Topography (2016)

  10. No Access

    Article

    NF-κB Upregulates Type 5 Phosphodiesterase in N9 Microglial Cells: Inhibition by Sildenafil and Yonkenafil

    Our previous studies showed that the phosphodiesterase-5 (PDE5) inhibitor sildenafil inhibited the microglial activation induced by lipopolysaccharide (LPS). However, whether yonkenafil, a novel PDE5 inhibitor...

    Siqi Zhao, **gyu Yang, Lixin Wang, Shengyi Peng, Jie Yin in Molecular Neurobiology (2016)

  11. No Access

    Article

    Mitochondrial Cyclophilin D as a Potential Therapeutic Target for Ischemia-Induced Facial Palsy in Rats

    Many studies have demonstrated that ischemia could induce facial nerve (FN) injury. However, there is a lack of a suitable animal model for FN injury study and thus little knowledge is available about the prec...

    Huizhen Chen, Chnagtao Liu, Jie Yin, Zhen Chen in Cellular and Molecular Neurobiology (2015)

  12. No Access

    Article

    Krüpple-like factors in the central nervous system: novel mediators in Stroke

    Transcription factors play an important role in the pathophysiology of many neurological disorders, including stroke. In the past three decades, an increasing number of transcription factors and their related ...

    Ke-Jie Yin, Milton Hamblin, Yanbo Fan, Jifeng Zhang in Metabolic Brain Disease (2015)

  13. No Access

    Article

    Protective effects of carbenoxolone are associated with attenuation of oxidative stress in ischemic brain injury

    Accumulating evidence has suggested that the gap junction plays an important role in the determination of cerebral ischemia, but the underlying mechanisms remain to be elucidated. In this study, we assessed th...

    Lang Zhang, Yu-Min Li, Yu-Hong **g, Shao-Yu Wang, Yan-Feng Song in Neuroscience Bulletin (2013)