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324 Result(s)
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Article
Mechanism of neurofibrillary degeneration in Alzheimer's disease
Neurofibrillary degeneration associated with the formation of intraneuronal neurofibrillary tangles of paired helical filaments (PHF) and 2.1 nm τ filaments is one of the most characteristic brain lesions of A...
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Article
Multiple Forms of Phosphatase from Human Brain: Isolation and Partial Characterization of Affi-Gel Blue Binding Phosphatases
Implication of protein phosphatases in Alzheimer disease led us to a systemic investigation of the identification of these enzyme activities in human brain. Human brain phosphatases eluted from DEAE-Sephacel w...
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Article
The report of Virtual Exhibition Software development
The main structure and key techniques of our Virtual Exhibition Software are summarized. It demonstrates the practice of Software Engineering during the development of our project and discusses the use of UML ...
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Article
Multiple Forms of Phosphatase from Human Brain: Isolation and Partial Characterization of Affi-Gel Blue Nonbinding Phosphatase Activities
Phosphatases extracted from a human brain were resolved into two main groups, namely affi-gel blue-binding phosphatases and affi-gel blue-nonbinding phosphatases. Affi-gel blue binding phosphatases were furthe...
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Article
Effect of Support and Acidity of Catalyst on the Direct Oxidation of Ethylene to Acetic Acid
The selective oxidation of ethylene to acetic acid was investigated on Pd-acid/ support catalyst system. The catalytic activity is influenced strongly by the acidity of the catalyst. The stronger the catalyst ...
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Article
Establishment and analyses on the unified horizontal crustal velocity fields in the Chinese mainland
The related data of GPS networks in the Chinese mainland and its peripheral areas are collected from internet sites in the paper. And various data fusion methods are presented based on the collected GPS data. ...
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Article
Model of rigid and elastic-plastic motion in intraplate blocks and strain status of principal blocks in Chinese mainland
The model of rigid and elastic-plastic motion and strain in intraplate blocks is established in the paper. The unique of strain parameters and minimum root-mean-square error of velocity residual of blocks are ...
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Article
An assessment for sustainable develo** capability of integrated agricultural regionalization in China
Based on the provincial units evaluation, this paper makes an assessment for sustainable develo** capability of the integrated agricultural regionalization in China. At first, an index system of agricultural...
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Article
Current horizontal strain field in Chinese mainland derived from GPS data
The current crustal horizontal strain field is given in the paper based on the horizontal movement rates obtained from about 400 GPS stations located in Chinese mainland and its surrounding areas. The results ...
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Article
Significance and mechanism of alzheimer neurofibrillary degeneration and therapeutic targets to inhibit this lesion
Abnormally hyperphosphorylated tau which is the major protein subunit of paired helical filaments (PHF)/neurofibrillary tangles is the pivotal lesion in Alzheimer disease (AD) and related tauopathies. The cose...
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Article
The wavelet transform of periodic function and nonstationary periodic function
Some properties of the wavelet transform of trigonometric function, periodic function and nonstationary periodic function have been investigated. The results show that the peak height and width in wavelet ener...
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Article
Effect of xiaoke granule on blood sugar and blood rheological property in experimental diabetic animals
To study the pharmacological effect of **aoke Granule on blood sugar and blood rheological property in the diabetic animals.
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Article
Up-regulation of cell division cycle (cdc) 2 kinase in neurons with early stage Alzheimer's disease neurofibrillary degeneration
The major component of Alzheimer's disease (AD) neurofibrillary tangles (NFTs) is abnormally hyperphosphorylated tau aggregated as paired helical filaments (PHFs). Cell division cycle (cdc) 2 kinase is one of...
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Article
Preparation, photoluminescence and thermal stability of sodium tris(pyridine dicarboxylato) europate(III) complex incorporated into silica matrix
Silica-based composite materials incorporated with sodium tris(pyridine dicarboxylato) europate(III), SiO2 : Na3Eu(DPA)3, where H2DPA is 2,6-pyridine dicarboxylic acid, were prepared by a sol-gel method. Photolum...
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Article
Alzheimer neurofibrillary degeneration
Neurofibrillary degeneration has primary and pivotal involvement in the pathogenesis of Alzheimer disease (AD) and other tauopathies. The inhibition of this lesion offers a promising therapeutic approach. The ...
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Article
Electroless copper plating process of N, N, N′, N′-tetrakis (2-hydroxypropyl) ethylenediamine system with high plating rate
Electroless copper plating process of N, N, N′, N′-tetrakis (2-hydroxypropyl) ethylenediamine (THPED) chelating agent was researched comprehensively. The results indicate that plating rate decreases with the i...
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Article
Spatial memory deficit and Tau hyperphosphorylation induced by inhibiting PP2A in rat brain
Hyperphosphorylation of Tau in Alzheimer’s disease (AD) brain appears to be caused by a down-regulation of protein phosphatase 2A (PP2A). In this study, we selectively inhibited PP2A by injection of okadaic ac...
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Article
Protective effect of ecdysterone on PC12 cells cytotoxicity induced by Beta-amyloid25–35
Objective: To examine the protective effect of ecdysterone (ECR) against beta-amyloid peptide fragment25–35 (Aß25–35)-induced PC12 cells cytotoxicity, and to further explore its mechanism.Methods: Experimental PC...
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Article
Diagnose Parameters of Plasma Induced by Femtosecond Laser Pulse in Quartz and Glasses
Electron plasma induced by a focused femtosecond pulse (130 fs, 800 nm) in quartz, fused silica, K9 glass, and Soda Lime glass was investigated by pump-probe technology. Pump and probe shadow imaging and inter...
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Bouguer gravity study of middle section of Tanlu fault
Although Tanlu fault is one of the most important tectonic fault zones and active earthquake belts in eastern China, little is known about its deep structure. In this study, we use the existing Bouguer gravity...