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  1. Article

    Open Access

    Prognostic implications of alpha-fetoprotein and C-reactive protein elevation in hepatocellular carcinoma following resection (PACE): a large cohort study of 2770 patients

    Routine clinical staging for hepatocellular carcinoma (HCC) incorporates liver function, general health, and tumor morphology. Further refinement of prognostic assessments and treatment decisions may benefit f...

    Kong-Ying Lin, Qing-**g Chen, Shi-Chuan Tang, Zhi-Wen Lin, Jian-** Zhang in BMC Cancer (2023)

  2. Article

    Open Access

    The genomic architecture of EBV and infected gastric tissue from precursor lesions to carcinoma

    Epstein-Barr virus (EBV)-associated gastric carcinomas (EBVaGCs) present unique molecular signatures, but the tumorigenesis of EBVaGCs and the role EBV plays during this process remain poorly understood.

    Zhang-Hua Chen, Shu-Mei Yan, **-** Chen, Qi Zhang, Shang-**n Liu in Genome Medicine (2021)

  3. Article

    Open Access

    Argonaute 2 and nasopharyngeal carcinoma: a genetic association study and functional analysis

    Argonaute 2 (AGO2), a central component of RNA-induced silencing complex, plays critical roles in cancer. We examined whether the single nucleotide polymorphisms (SNPs) of AGO2 were related to the risk of nasopha...

    Peiyao Li, **feng Meng, Yun Zhai, Hongxing Zhang, Lixia Yu, Zhifu Wang in BMC Cancer (2015)

  4. Article

    Open Access

    Nimotuzumab promotes radiosensitivity of EGFR-overexpression esophageal squamous cell carcinoma cells by upregulating IGFBP-3

    Epidermal growth factor receptor (EGFR) is suggested to predict the radiosensitivity and/or prognosis of human esophageal squamous cell carcinoma (ESCC). The objective of this study was to investigate the effi...

    Lei Zhao, Li-Ru He, Mian **, Mu-Yan Cai in Journal of Translational Medicine (2012)

  5. Article

    Open Access

    Up-regulation of METCAM/MUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells

    Conflicting research has identified METCAM/MUC18, an integral membrane cell adhesion molecule (CAM) in the Ig-like gene super-family, as both a tumor promoter and a tumor suppressor in the development of breas...

    Guo-fang Zeng, Shao-xi Cai, Guang-Jer Wu in BMC Cancer (2011)

  6. Article

    Open Access

    Genetic polymorphisms of TLR3 are associated with Nasopharyngeal carcinoma risk in Cantonese population

    Nasopharyngeal carcinoma is endemic in Southern China, displays a strong relationship with genetic susceptibility and associates with Epstein-Barr virus infection. Toll-like receptor 3 (TLR3) plays an importan...

    Jun-Fang He, Wei-Hua Jia, Qin Fan, **n-** Zhou, Hai-De Qin, Yin Yao Shugart in BMC Cancer (2007)

  7. Article

    Open Access

    Genetic polymorphisms of CYP2A13 and its relationship to nasopharyngeal carcinoma in the Cantonese population

    Nasopharyngeal carcinoma (NPC) is characterized by a high prevalence in Southern China, especially among Cantonese individuals of the Guangdong Province. Epidemiological studies have suggested that frequent ex...

    Ju-Hong Jiang, Wei-Hua Jia, Han-Kui Chen in Journal of Translational Medicine (2004)