4 Result(s)
within
Article
**-li Lu
Human Genetics
Neurology
Neurosciences
Psychiatry
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Article
Open AccessFunctional relationships between recessive inherited genes and genes with de novo variants in autism spectrum disorder
Both de novo variants and recessive inherited variants were associated with autism spectrum disorder (ASD). This study aimed to use exome data to prioritize recessive inherited genes (RIGs) with biallelically ...
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Article
Open AccessInherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model
We previously performed targeted sequencing of autism risk genes in probands from the Autism Clinical and Genetic Resources in China (ACGC) (phase I). Here, we expand this analysis to a larger cohort of patien...
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Article
Open AccessResveratrol ameliorates prenatal progestin exposure-induced autism-like behavior through ERβ activation
Recent literatures indicate that maternal hormone exposure is a risk factor for autism spectrum disorder (ASD). We hypothesize that prenatal progestin exposure may counteract the neuroprotective effect of estr...
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Article
Open AccessAutism-associated gene Dlgap2 mutant mice demonstrate exacerbated aggressive behaviors and orbitofrontal cortex deficits
As elegant structures designed for neural communication, synapses are the building bricks of our mental functions. Recently, many studies have pointed out that synaptic protein-associated mutations may lead to...
