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Clinical outcomes of carbapenem-resistant gram-negative bacterial bloodstream infection in patients with end-stage renal disease in intensive care units: a multicenter retrospective observational study

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  1. Article

    Open Access

    Dissecting the vascular-cognitive nexus: energetic vs. conventional hemodynamic parameters

    Blood pressure or flow measurements have been associated with vascular health and cognitive function. We proposed that energetic hemodynamic parameters may provide a more nuanced understanding and stronger cor...

    Hao-Min Cheng, Jiun-Jr Wang, Shao-Yuan Chuang, Chen-Hua Lin in Hypertension Research (2024)

  2. Article

    Open Access

    Deep Learning–Based Localization and Detection of Malpositioned Nasogastric Tubes on Portable Supine Chest X-Rays in Intensive Care and Emergency Medicine: A Multi-center Retrospective Study

    Malposition of a nasogastric tube (NGT) can lead to severe complications. We aimed to develop a computer-aided detection (CAD) system to localize NGTs and detect NGT malposition on portable chest X-rays (CXRs)...

    Chih-Hung Wang, Tianyu Hwang, Yu-Sen Huang in Journal of Imaging Informatics in Medicine (2024)

  3. Article

    Open Access

    Exome sequencing and genome-wide association analyses unveils the genetic predisposition in hydroxychloroquine retinopathy

    To unveil the candidate susceptibility genes in chloroquine/hydroxychloroquine (CQ/HCQ) retinopathy using whole exome sequencing (WES) and genome-wide association study (GWAS).

    Hsun-I Chiu, Hui-Chen Cheng, Chih-Chiau Wu, Shih-Jen Chen, De-Kuang Hwang in Eye (2024)

  4. Article

    Open Access

    Duck STING mediates antiviral autophagy directing the interferon signaling pathway to inhibit duck plague virus infection

    Migratory birds are important vectors for virus transmission, how migratory birds recognize viruses and viruses are sustained in birds is still enigmatic. As an animal model for waterfowl among migratory birds...

    Bin Tian, Yanming Tian, Xuetong Wang, Dongjie Cai, Li** Wu in Veterinary Research (2024)

  5. Article

    Open Access

    Brain effect mechanism of lever positioning manipulation on LDH analgesia based on multimodal MRI: a study protocol

    The clinical symptoms of Lumbar Disc Herniation (LDH) can be effectively ameliorated through Lever Positioning Manipulation (LPM), which is closely linked to the brain's pain-regulating mechanisms. Magnetic Re...

    **ng-chen Zhou, Long-hao Chen, Shuang Wu in BMC Complementary Medicine and Therapies (2024)

  6. Article

    Open Access

    Effect of probiotics on children with autism spectrum disorders: a meta-analysis

    Researches have found that alteration of intestinal flora may be closely related to the development of autism spectrum disorder (ASD). However, whether probiotics supplementation has a protective effect on ASD...

    ** Zeng, Cheng-zhi Zhang, Zhi-xing Fan, Chao-jun Yang in Italian Journal of Pediatrics (2024)

  7. Article

    Open Access

    **nbao Pill ameliorates heart failure via regulating the SGLT1/AMPK/PPARα axis to improve myocardial fatty acid energy metabolism

    Heart failure (HF) is characterized by a disorder of cardiomyocyte energy metabolism. **nbao Pill (XBW), a traditional Chinese medicine formulation integrating “Liushen Pill” and “Shenfu Decoction,” has been a...

    Linjie Pan, Zhanchi Xu, Min Wen, Minghui Li, Dongxin Lyu, Haiming **ao in Chinese Medicine (2024)

  8. Article

    Open Access

    Correction: Preoperative handgrip strength can predict early postoperative shoulder function in patients undergoing arthroscopic rotator cuf repair

    Yu-Cheng Liu, Shu-Wei Huang in Journal of Orthopaedic Surgery and Research (2024)

  9. Article

    Open Access

    Association between socioeconomic and motherhood characteristics with receiving community-based treatment services among justice-involved young female drug users: a retrospective cohort study in Taiwan

    Drug-involved individuals who contact treatment services in Taiwan are mostly driven by criminal justice systems either as an alternative or adjunct to criminal sanctions for a drug offence. With a focus on ju...

    Chuan-Yu Chen, Tan-Wen Hsieh, Wenmay Rei, Cheng-Hsiung Huang in Harm Reduction Journal (2024)

  10. Article

    Open Access

    Real-World Efficacy and Safety of Universal 8-Week Glecaprevir/Pibrentasvir for Treatment-Naïve Patients from a Nationwide HCV Registry in Taiwan

    Eight-week glecaprevir/pibrentasvir (GLE/PIB) is indicated for treatment-naïve (TN) patients with chronic hepatitis C (CHC), with or without compensated cirrhosis. Given that the Taiwanese government is commit...

    Chun-Chi Yang, Chung-Feng Huang, Te-Sheng Chang in Infectious Diseases and Therapy (2024)

  11. Article

    Open Access

    Sacubitril/valsartan improves all-cause mortality in heart failure patients with reduced ejection fraction and chronic kidney disease

    Impaired renal function is frequently observed in patients with heart failure and reduced ejection fraction (HFrEF). The differential effect of sacubitril/valsartan and angiotensin-converting enzyme inhibitors...

    Wei-Chieh Lee, Ting-Wei Liao, Tien-Yu Chen in Cardiovascular Drugs and Therapy (2024)

  12. Article

    Open Access

    Enabling the design of surgical instruments for under-resourced patients through metal additive manufacturing: ulnar shortening osteotomy as an example

    Ulnar shortening osteotomy (USO) has demonstrated good outcomes for patients with ulnar impaction syndrome. To minimize complications such as non-union, precise osteotomy and firm fixation are warranted. Despi...

    Kuan-Lin Chen, Cheng-Yu Yin, Hui-Kuang Huang, Yi-Chao Huang in 3D Printing in Medicine (2024)

  13. Article

    Open Access

    Shock index to predict outcomes in patients with trauma following traffic collisions: a retrospective cohort study

    Taiwan, which has a rate of high vehicle ownership, faces significant challenges in managing trauma caused by traffic collisions. In Taiwan, traffic collisions contribute significantly to morbidity and mortali...

    Te-Kai Liao, Chung-Han Ho, Ying-Jia Lin in European Journal of Trauma and Emergency S… (2024)

  14. Article

    Open Access

    Sustainability of exercise-induced benefits on circulating MicroRNAs and physical fitness in community-dwelling older adults: a randomized controlled trial with follow up

    Circulating miRNAs (c-miR) have been shown to be potential biomarkers in sarcopenia, but the miRNAs response to aerobic exercise in older people remains inconclusive. We sought to examine the exercise benefits...

    Li-Yuan Huang, Ai Yin Lim, Chih-Chin Hsu, Yun-Fang Tsai, Tieh-Cheng Fu in BMC Geriatrics (2024)

  15. Article

    Open Access

    A simplified herbal decoction attenuates myocardial infarction by regulating macrophage metabolic reprogramming and phenotypic differentiation via modulation of the HIF-1α/PDK1 axis

    Myocardial infarction (MI) poses a global public health challenge, often associated with elevated mortality rates and a grim prognosis. A crucial aspect of the inflammatory injury and healing process post-MI i...

    Zhi-jun Lin, **n Dong, Huan He, Jia-lin Jiang, Zhuo-ji Guan, Xuan Li in Chinese Medicine (2024)

  16. Article

    Open Access

    Long-term prosthetic-associated subclinical thrombotic events evaluation by cardiac CTA after transcatheter aortic valve implantation: incidence and outcomes

    To observe prosthetic-associated subclinical thrombotic events (PASTE) after transcatheter aortic valve implantation (TAVI) by cardiac CTA, and assess their impact on long-term patient outcomes.

    Qi**g Zhou, Jiaqi Wen, Qifeng Zhu, Jiaqi Fan, **aojun Guan in Insights into Imaging (2024)

  17. Article

    Open Access

    Sustainable Implementation of Physician-Pharmacist Collaborative Clinics for Diabetes Management in Primary Healthcare Centers: A Qualitative Study

    Although physician-pharmacist collaborative clinics for diabetes management have been shown to be effective and cost-effective worldwide, there is limited understanding of the factors that influence their sust...

    Jie **ao, Shuting Huang, Qing Wang in Journal of Epidemiology and Global Health (2024)

  18. Article

    Open Access

    Chief complaints and computed tomography results in the emergency department: a three-year retrospective cohort study

    Computed tomography (CT) is frequently performed in the patients who admitted to the emergency department (ED), discharged but returned to ED within 72 h. It is unknown whether the main complaints of patients ...

    Cheng-Yi Fan, Chi-Hsin Chen, Jiun-Wei Chen, Jia-How Chang in BMC Emergency Medicine (2024)

  19. Article

    Open Access

    IL-2-free tumor-infiltrating lymphocyte therapy with PD-1 blockade demonstrates potent efficacy in advanced gynecologic cancer

    Tumor-infiltrating lymphocyte (TIL) therapy has been restricted by intensive lymphodepletion and high-dose intravenous interleukin-2 (IL-2) administration. To address these limitations, we conducted preclinica...

    **g Guo, Chunyan Wang, Ning Luo, Yuliang Wu, Wei Huang, Jihui Zhu in BMC Medicine (2024)

  20. Article

    Open Access

    P. gingivalis in oral-prostate axis exacerbates benign prostatic hyperplasia via IL-6/IL-6R pathway

    Benign prostatic hyperplasia (BPH) is the most common disease in elderly men. There is increasing evidence that periodontitis increases the risk of BPH, but the specific mechanism remains unclear. This study a...

    Shuang-Ying Wang, Yi Cai, **ao Hu, Fei Li, **n-Hang Qian in Military Medical Research (2024)

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