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Cancer Classification with Microarray Data Using Support Vector Machines
Microarrays (Schena et al. 1995) are also called gene chips or DNA chips. On a microarray chip, there are thousands of spots. Each spot contains the...
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Random Voronoi Ensembles for Gene Selection in DNA Microarray Data
Currently, cancer and other complex pathologies are analyzed mainly by morphological classification. In the past few decades there have been dramatic...
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Class Prediction with Microarray Datasets
Microarray technology is having a significant impact in the biological and medical sciences and class prediction will play an increasingly important...
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Molecular responses of higher plants to dehydration
A massive amount of data has been accumulating on the molecular responses of plants to water deficit. In plants, dehydration activates a protective...
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Heavy metal signalling in plants: linking cellular and organismic responses
Heavy metals are required in plants as essential micronutrients or act as toxic compounds. How do plants perceive heavy metals and which signalling...
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Introduction
Everywhere in the world, environmental stresses represent the most limiting factors for agricultural productivity. Besides plant-specific endogenous...
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Advanced Targeting Strategies for Murine Retroviral and Adeno-associated Viral Vectors
Targeted gene delivery involves broadening viral tropism to infect previously nonpermissive cells, replacing viral tropism to infect a target cell...
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Nonviral Delivery of Cancer Genetic Vaccines
The potential use of genetic vaccines to address numerous diseases including cancer is promising, but currently unrealized. Here, we review...
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Genetic Algorithms and Genetic Linkage
This chapter provides a summary of fundamental materials on genetic algorithms. It presents definitions of genetic algorithm terms and briefly...
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Production and Formulation of Adenovirus Vectors
Adenovirus vectors have attracted considerable interest over the past decade, with ongoing clinical development programs for applications ranging...
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Molecular Conjugates
Molecular conjugates are nanometer-sized entities consisting of synthetic materials (lipids, polycations, targeting agents, and so on) and nucleic...
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Genetic Linkage Learning Techniques
The importance of learning genetic linkage has been discussed in the previous chapter and recognized in the field of genetic and evolutionary...
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A Dynamic Model of Gene Regulatory Networks Based on Inertia Principle
In molecular biology, functions are produced by a set of macromolecules that interact at different levels. Genes and their products, proteins,...
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Regeneration of Urologic Tissues and Organs
Patients suffering from a variety of urologic diseases may be treated with transplanted tissues and organs. However, there is a shortage of donor...
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Fluorescence Correlation Spectroscopy with Autofluorescent Proteins
Fluorescence correlation spectroscopy (FCS) is a versatile technique operating at the single-molecule level, that successfully meets many challenges...
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Fish and Shellfish Upgrading, Traceability
Recognition of the limited biological resources and the increasing environmental pollution has emphasised the need for better utilisation of...
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Stress Induced by Recombinant Protein Production in Escherichia coli
Strong production of recombinant proteins interferes with cellular processes in many ways. Drainage of precursors and energy urges the cell to...
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Roles of Heat-Shock Chaperones in the Production of Recombinant Proteins in Escherichia coli
Escherichia coli is a versatile organism for the production of recombinant proteins. Often, however, the recombinant protein does not reach its...
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Clarification of Interactions among Microorganisms and Development of Co-culture System for Production of Useful Substances
Co-culture systems containing two microorganisms for the production of useful substances are described. We developed a novel co-culture system...
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Bacterial Capsular Polysaccharide and Sugar Transferases
Capsular polysaccharides (CPs) of several pathogenic bacteria are thought to be good materials for the development of new therapeutic reagents. These...