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11 Plant sphingolipids
Plants contain a multiplicity of sphingolipid metabolites, such as long-chain bases, long-chain base phosphates, ceramides, glycosylceramides,... -
12 Baker’s Yeast: a rising foundation for eukaryotic sphingolipid-mediated cell signaling
Saccharomyces cerevisiae has been an invaluable tool for the dissection of sphingolipid metabolic pathways and cloning of enzymes involved in... -
5 Sterol metabolism and functions in higher plants
Higher plants synthesize a bewildering array of sterols, with sitosterol, stigmasterol, and 24-methylcholesterol as major compounds. All plant... -
6 Sterol biochemistry and regulation in the yeast Saccharomyces cerevisiae
Saccharomyces cerevisiae has been a major model system for the study of sterol biosynthesis and function. All of the genes encoding the enzymes... -
7 Mammalian ACAT and DGAT2 gene families
Mammalian isozymes of ACAT, DGAT, and MGAT are encoded by the ACAT and DGAT2 gene families. These enzymes catalyze the synthesis of neutral lipid... -
Critical Phenomena in a Small World
We consider the behavior of various systems on a small-world network near a critical point. Our starting point is a different, nonrandom system with... -
Who Is the Best Connected Scientist?A Study of Scientific Coauthorship Networks
Using data from computer databases of scientific papers in physics, biomedical research, and computer science, we have constructed networks of... -
Scholarly Information Network
I review the background and some recent trends of a particular scholarly information network, ar**v.org, and discuss some of its implications for new... -
Spectral Analysis of Random Networks
We review a general approach that describes the spectra of eigenvalues for random graphs with a local tree-like structure. The exact equations to the... -
Theoretical Neuroanatomy:Analyzing the Structure, Dynamics,and Function of Neuronal Networks
The mammalian brain is an extraordinary object: its networks give rise to our conscious experiences as well as to the generation of adaptive behavior... -
Information Theory of Complex Networks: On Evolution and Architectural Constraints
Complex networks are characterized by highly heterogeneous distributions of links, often pervading the presence of key properties such as robustness... -
Course 14: Hiking through Glassy Phases: Physics beyond Aging
Experiments performed on a wide range of glassy materials display many interesting phenomena, such as aging behavior. In recent years, a large body... -
Course 6: Glasses, Replicas and All That
In these lectures I will review the approach to glasses based on the replica formalism. Many of the physical ideas are very similar to those of older... -
Regulation of IP 3 Receptors by IP 3 and Ca 2+
Inositol 1,4,5-trisphosphate ( IP 3) receptors are intracellular Ca 2+ channels that mediate release of Ca 2+ from intracellular stores. The channels... -
Modeling Calcium Waves
We present an introduction to the mathematics of calcium waves, both intracellular and intercellular. After a discussion of the earlier models I... -
Hormone-Mediated Intercellular Calcium Signalling in an Insect Salivary Gland – Pathways and Mechanisms
The salivary glands of the blowfly Calliphora vicina are a favourable preparation for investigations into spatio-temporal Ca 2+ dynamics in an intact... -
Course 1: Nonequilibrium Phase Transitions
Nonequilibrium phase transitions are discussed with emphasis on general features such as the role of detailed balance violation in generating... -
Course 2: Mechanical Aging and Non-linear Rheology of Concentrated Colloidal Suspensions: Experimental Facts and Simple Models
Many colloidal systems display very non-Newtonian and solid-like behaviour when concentrated, a striking feature being the apparition of a yield... -
From Simple to Complex Ca 2+ Oscillations: Regulatory Mechanisms and Theoretical Models
Intracellular Ca 2+ oscillations most often appear as regular spikes. However, complex Ca 2+ oscillations in the form of bursting or chaos have also... -
S. cerevisiae K28 toxin – a secreted virus toxin of the A/B family of protein toxins
Since the initial discovery of toxin-secreting killer strains in the yeast Saccharomyces cerevisiae more than 40 years ago, continuous research on...