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Prototypic Reactions of Prokaryotic Carbon Catabolism
Metabolic pathways are mosaics of a limited set of prototypic reactions occurring in a sequence that is based on structural features of a substrate...
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Microbial Kinetics
It’s all about fluxes and rates! Environmental resources are available to microbes in form of fluxes of energy and matter. Some important intrinsic...
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Microbial Life on Earth, Metabolism, and Metabolic Diversity
Metabolism confers fitness to a microbe. The features of metabolism, including its diversity, can be easily understood as the result of a microbe’s...
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Nanoparticles and Toxicity
Nanotoxicology studies the potential toxic effects on the environment and human health of nanomaterials and nanoparticles. Numerous materials which...
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Staphylococcus aureus
Microorganisms in the genus Staphylococcus were firstly discovered in 1870 by Sir Alexander Ogston (1844–1929) who examined via optical microscopy...
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Post scriptum
The tribute to Dr. Didenko does not conclude with the end of our voyage in the bacteria and nanoparticle world. Both Dr. Didenko’s memory and...
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Nanoworld
The term “nanotechnology” was coined by Norio Taniguchi in 1974, but it was Richard Feynman in December 1959 that actually founded the concept of...
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Gastric Colonization by H. pylori
Helicobacter pylori (H. pylori) is uniquely adapted to colonize the gastric mucosa. The key components for gastric colonization include motility,...
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Extragastric Manifestations of H. pylori Infection: Lower GI Disorders
Possible association has been suggested between Helicobacter pylori (H. pylori) infection and some of the lower gastrointestinal (GI) tract diseases....
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Specific Conditions: Children
Helicobacter pylori (H. pylori) infection is usually acquired during childhood, causing various diseases even in children. When applying diagnostic...
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Change of Acid Secretions, Ghrelin, and Leptin, by H. pylori
When Helicobacter pylori (H. pylori) begins to colonize on the surface of the gastric epithelium, H. pylori induces strong inflammatory responses and...
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Gastric Cancer: Epithelial-Mesenchymal Transition
An epithelial-mesenchymal transition (EMT) induces loss of epithelial cell polarity and change of cell phenotype from typical cubical shape into...
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Gastric Cancer: Genetic Alternations Induced by H. pylori Infection: The Role of Activation-Induced Cytidine Deaminase
Oxidative stress and aberrant activation-induced cytidine deaminase (AID) expression induced by chronic inflammation play an important role in...
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Extraintestinal Manifestations of H. pylori Infection: Idiopathic Thrombocytopenic Purpura
Epidemiologic studies, randomized controlled studies, and meta-analyses have reported an association between idiopathic thrombocytopenic purpura...
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Gastric Cancer: H. pylori and Macrophage Migration Inhibitory Factor
Macrophage migration inhibitory factor (MIF) is known to have an important role in angiogenesis, lymph node metastasis, tumor invasion, and distant...
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Extraintestinal Manifestations of H. pylori Infection: Heart Disease
Since the discovery that Helicobacter pylori (H. pylori) is a central player in the pathogenesis of gastric and duodenal ulcers, there have been many...
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Metronidazole
Metronidazole is one of the major antibiotics for the eradication of Helicobacter pylori (H. pylori). The metronidazole resistance rate of H. pylori...
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Peptic Ulcer Disease
Since the discovery of Helicobacter pylori (H. pylori), H. pylori eradication has dramatically lowered the recurrence rate of peptic ulcer disease...
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Secondary Prevention of Gastric Cancer After Endoscopic or Surgical Treatment
Few reports have shown survival improvements after Helicobacter pylori (H. pylori) eradication in patients treated with surgery in the early gastric...
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Histopathologic Diagnosis of H. pylori Infection and Associated Gastric Diseases
Helicobacter pylori (H. pylori) can be diagnosed by histopathologic examination, which is considered to be a standard method, since not only it...