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Alginate Nanoparticles: A Potential Drug Carrier in Tuberculosis Treatment
Among all infectious diseases that afflict humans, tuberculosis (TB) remains the deadliest. At present, epidemiologists estimate that one-third of...
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Dendrimers-Based Drug Delivery in Tuberculosis
Tuberculosis (TB) is a disease caused by a microorganism (Mycobacterium tuberculosis) which invades the lungs and initiates the disease. Currently,...
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Solid Lipid Nanoparticles in Tuberculosis
Tuberculosis (TB) is a deadly disease spread by single infection agents. It creates a huge burden on the healthcare system for the development of...
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Global Health and Malaria: Past and Present
Although malaria is a curable and preventable disease, it has wreaked havoc across the globe, affecting millions of people’s lives for decades since...
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Surface-Modified Drug Delivery Systems in Malaria
Due to the large number of individuals afflicted, the intricacy of the causative agent life cycle, the protist Plasmodium sp., and the severity of...
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Clinical Trials in Malaria
Clinical trials are the final and most important phase in the process of new drug development against any disease or disorder. Due to the development...
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Polymeric Nanoparticles in Malaria
The major reason behind malaria becoming one of the most serious infectious diseases is the limitations of available antimalarial therapy. Drug...
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Solid Lipid Nanoparticles in Malaria
Malaria is a serious infectious disease that is caused due to Plasmodium parasites and is one of the major reasons for mortality due to infectious...
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Potential of Micro-/Nanoemulsions as a Delivery Carrier to Treat Malaria
Malaria is a serious disease that exists since centuries. The drugs available for malaria therapy hold poor aqueous solubility and bioavailability...
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Malaria – Current Treatment Options
Malaria diseases are caused by Plasmodium, either P. falciparum or non-P. falciparum requires antimalarial treatment guidelines. Artemisinin-based...
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Antimalarial Drug Resistance: Trends, Mechanisms, and Strategies to Combat Antimalarial Resistance
Malaria is among the most prevalent parasite infections caused by Plasmodium genus. According to the most recent data available for the year 2020,...
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Liposomal Drug Delivery in Malaria
Malaria is one of the greatest health challenges worldwide and produces a great challenge to formulation scientists. Poor rate of development in the...
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Polymers, Particles and Conjugates
Due to the inability to dose glucocorticoid receptor modulators (GRMs) chronically as a result of their unwanted side effects, the use of polymers,...
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Prodrugs
Prodrugs are a widely deployed strategy for medical chemists. Introduction of the prodrug typically moderates the physicochemical properties of the...
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Tailoring Vaccines for Older Individuals: Aging of the Immune System and the Impact on Vaccine Efficacy
Tailoring vaccines to the older population (>65 yrs) is an emerging subject that has gained momentum over the past decade. The vaccine efficacy of a...
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3D Printing: Advancements in the Development of Personalised Pharmaceuticals for Older Adults
Three-dimensional (3D) printing is a revolutionary additive manufacturing technology that constructs objects layer-by-layer. This versatile...
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The Ageing Microbiome, Pharmaceutical Considerations, and Therapeutic Opportunities
Research in recent years has illuminated the importance of the microbiome for human wellbeing and healthy ageingHealthy ageing. Numerous age-related...
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Starting Materials for Manufacturing the Biopharmaceutical Drug Substance
Starting materials (also referred to as source materials) are the starting point for cGMP manufacturing of the biopharmaceutical drug substance. Some...
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New Drugs in Synthesis Research for Viral Diseases
In 1901, the yellow fever virus was one of the first viruses to be discovered by humans. Since then, over a century of research has been dedicated...
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Hepatitis C: Exploration of Diseases, Diagnosis, and Treatment Strategies
By reading this chapter, readers will be able to understand what is hepatitis and how it affects different patients, and on prior treatment,...