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Genome analysis of multidrug resistant Enterococcus faecium and Enterococcus faecalis circulating among hospitalized patients in uMgungundlovu District, KwaZulu-Natal, South Africa
BackgroundVancomycin-resistant enterococci (VRE) are important pathogens categorized as high-priority bacteria in the Global Priority List of...
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Association between asthma and COVID-19 severity during Omicron epidemic: a retrospective cohort study using real-world data
BackgroundThe available evidence presented inconsistencies and inconclusive findings regarding the associations between co-existing asthma and...
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A secondary abdominal aorta-duodenal fistula accompanied with acquired Immune Deficiency Syndrome presented with recurrent sepsis: a case report
BackgroundAbdominal aorta-duodenal fistulas are rare abnormal communications between the abdominal aorta and duodenum. Secondary abdominal...
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Characteristics and outcomes of patients with COVID-19 at high risk of disease progression receiving sotrovimab, oral antivirals, or no treatment: a retrospective cohort study
BackgroundThe clinical benefit of coronavirus disease 2019 (COVID-19) treatments against new circulating variants remains unclear. We sought to...
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Diagnostic accuracy of the Xpert® MTB/XDR assay for detection of Isoniazid and second-line antituberculosis drugs resistance at central TB reference laboratory in Tanzania
IntroductionEarly diagnosis of tuberculosis (TB) and universal access to drug-susceptibility testing (DST) are critical elements of the WHO End TB...
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A case report and literature review: Mycobacterium leprae infection diagnosed by metagenomic next-generation sequencing of cerebrospinal fluid
BackgroundLeprosy is a chronic infectious disease caused by Mycobacterium leprae ( M. leprae ) that is responsible for deformities and irreversible...
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Cytokines assets in PLWH in two-drug dolutergravir based or three-drug antiretroviral regimen
To minimize the toxicity and impact of combined antiretroviral therapy (cART) on the lifestyle of people living with Human Immunodeficiency Virus...
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Assessing the relationship between malaria incidence levels and meteorological factors using cluster-integrated regression
This paper introduces a novel approach to modeling malaria incidence in Nigeria by integrating clustering strategies with regression modeling and...
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Reduction in ACE2 expression in peripheral blood mononuclear cells during COVID-19 – implications for post COVID-19 conditions
BackgroundSevere COVID-19 is uncommon, restricted to 19% of the total population. In response to the first virus wave (alpha variant of SARS-CoV-2),...
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Forecasting and map** dengue fever epidemics in China: a spatiotemporal analysis
BackgroundDengue fever (DF) has emerged as a significant public health concern in China. The spatiotemporal patterns and underlying influencing its...
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Overwintering West Nile virus in active Culex pipiens mosquito populations in Greece
The flavivirus West Nile Virus (WNV), which is transmitted by mosquitoes, poses a significant threat to both humans and animals, and its outbreaks...
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Slow recovery rates and spatial aggregation of Triatoma infestans populations in an area with high pyrethroid resistance in the Argentine Chaco
BackgroundThe emergence of pyrethroid resistance has threatened the elimination of Triatoma infestans from the Gran Chaco ecoregion. We investigated...
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Intestinal microbiota imbalance resulted by anti-Toxoplasma gondii immune responses aggravate gut and brain injury
BackgroundToxoplasma gondii infection affects a significant portion of the global population, leading to severe toxoplasmosis and, in...
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Comparison of microscopic and xpert MTB diagnoses of presumptive mycobacteria tuberculosis infection: retrospective analysis of routine diagnosis at Cape Coast Teaching Hospital
IntroductionTuberculosis is a global health problem that causes 1. 4 million deaths every year. It has been estimated that sputum smear-negative...
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Is Culex modestus a New Usutu virus vector?
Usutu virus is an emerging pathogen transmitted by mosquitoes. Culex modestus mosquitoes are widespread in Europe, but their role in disease...
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Liver autotransplantation and atrial reconstruction on a patient with multiorgan alveolar echinococcosis: a case report
BackgroundAlveolar echinococcosis (AE) primarily affects the liver and potentially spreads to other organs. Managing recurrent AE poses significant...
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Mitochondrial genome of the fluke pond snail, Austropeplea cf. brazieri (Gastropoda: Lymnaeidae)
BackgroundLymnaeid snails of the genus Austropeplea are an important vector of the liver fluke ( Fasciola hepatica ), contributing to livestock...
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Emerging paradigms: unmasking the role of oxidative stress in HPV-induced carcinogenesis
The contribution of the human papillomavirus (HPV) to cancer is significant but not exclusive, as carcinogenesis involves complex mechanisms, notably...
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Epidemiology of Citrobacter spp. infections among hospitalized patients: a systematic review and meta-analysis
BackgroundInfections due to Citrobacter species are increasingly observed in hospitalized patients and are often multidrug-resistant. Yet, the...